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Categories: Biology: Microbiology, Engineering: Biometric
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
(via sciencedaily.com) Original source Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes
(via sciencedaily.com) The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.
Published Decreasing biodiversity may promote spread of viruses
(via sciencedaily.com) Original source How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.
Published Genetically engineering associations between plants and nitrogen-fixing microbes could lessen dependence on synthetic fertilizer
(via sciencedaily.com) Original source Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.
Published Antibiotics can help some bacteria survive for longer
(via sciencedaily.com) Original source Scientists have found a surprising effect of some antibiotics on certain bacteria -- that the drugs can sometimes benefit bacteria, helping them live longer.
Published By air, rain and land: How microbes return after a wildfire
(via sciencedaily.com) Ecological disturbances like wildfires disrupt microbial communities. Researchers found that dispersal played a pivotal role in re-establishing surface-level communities.
Published Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors
(via sciencedaily.com) Original source Researchers have made an important finding about Aedes aegypti mosquitoes -- one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.
Published New strategies reduce treatment failure in malaria by up to 81%
(via sciencedaily.com) Original source To slow artemisinin resistance and reduce treatment failures, an international research team investigated various drug policy interventions in Rwanda, where artemisinin resistance was first reported in 2020. Among other strategies, the team found that next-generation interventions such as triple ACTs (TACTs) -- which combine an artemisinin derivative with two partner drugs or which use a sequential course of one ACT formulation, followed by a different ACT formulation -- resulted in treatment failure counts that were at least 81% lower.
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage
(via sciencedaily.com) Original source Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Nanoparticles made from plant viruses could be farmers' new ally in pest control
(via sciencedaily.com) Engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, the researchers created nanoparticles that can deliver pesticide molecules to previously inaccessible depths in the soil. This 'precision farming' approach could potentially minimize environmental toxicity and cut costs for farmers.
Published How climate warming could disrupt a deep-rooted relationship
(via sciencedaily.com) Trees depend on fungi for their well-being. As climate change and global warming cause higher temperatures and amplified drought, little is known about how these important fungi will respond. To investigate this issue, a research team conducted a climate change experiment where they exposed boreal and temperate tree species to warming and drought treatments to better understand how fungi and their tree hosts respond to environmental changes. Their findings revealed that the combined effects of warming and water stress will likely result in major disturbances of ectomycorrhizal networks and may harm forest resilience and function.
Published Split gene-editing tool offers greater precision
(via sciencedaily.com) To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.
Published Compound derived from hops reduces abundance of gut microbe associated with metabolic syndrome
(via sciencedaily.com) Original source Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.
Published Unzipping mRNA rallies plant cells to fight infection
(via sciencedaily.com) Original source Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.
Published New study finds that sewage release is worse for rivers than agriculture
(via sciencedaily.com) Original source Sewage pollution, whether treated or untreated, was found to be the primary driver of increased nutrients, algae, and sewage fungus in rivers. Sewage discharge also radically altered plant, animal, and microbe communities, increasing the abundance of harmful species. Run-off from agriculture was also found to lower water quality and be particularly harmful for sensitive insect groups.
Published Genetically modifying individual cells in animals
(via sciencedaily.com) Original source Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Published Slow growth in crocodile ancestors pre-dated their semi-aquatic lifestyle
(via sciencedaily.com) Original source A groundbreaking study is reshaping our understanding of crocodile evolution by pinpointing the onset of slow growth rates to the Late Triassic period, much earlier than the previously assumed Early Jurassic timeline. The research highlights newly discovered fossil crocodile ancestors (known as crocodylomorphs) that exhibited slow growth rates, similar to modern-day crocodilians. Intriguingly, these early crocodylomorphs were not the lethargic, semi-aquatic creatures we are familiar with today; they were small, active, and fully terrestrial. The study also suggests that this slow-growth strategy was not a mere evolutionary quirk but a survival mechanism, as only the slow-growing crocodylomorphs managed to survive the End-Triassic mass extinction. This stands in stark contrast to the fast-growing dinosaurs of the same era, setting the stage for the divergent evolutionary paths that would later define their modern descendants.
Published A newly identified virus emerges from the deep
(via sciencedaily.com) Original source Marine virologists analyzed sediment from the Mariana Trench, the deepest place on Earth, and identified a new bacteriophage.
Published Spider silk is spun by silkworms for the first time, offering a green alternative to synthetic fibers
(via sciencedaily.com) Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.
Published Researchers issue urgent call to save the world's largest flower -Rafflesia -- from extinction
(via sciencedaily.com) Original source A new study finds that most Rafflesia species, which produce the world's largest flowers, face extinction. Lack of protection at local, national, and international levels means that remaining populations are under critical threat.