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Categories: Biology: Microbiology, Engineering: Biometric
Published Some hosts have an 'evolutionary addiction' to their microbiome
(via sciencedaily.com) Original source We've long known that hosts malfunction without their microbiome -- whether they are missing key microbial species or are completely microbe free. This malfunctioning is usually explained by the need for microbes to perform unique and beneficial functions, but evolutionary ecologist is questioning that narrative.
Published AI-powered triage platform could aid future viral outbreak response
(via sciencedaily.com) Original source A team of researchers has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.
Published Enhancing cancer therapy using functionalized photosynthetic bacteria
(via sciencedaily.com) Original source Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action.
Published Common origin behind major childhood allergies
(via sciencedaily.com) Original source Several major childhood allergies may all stem from the community of bacteria living in our gut, according to a new study. The research identifies gut microbiome features and early life influences that are associated with children developing any of four common allergies -- eczema, asthma, food allergy and/or hay fever. The findings could lead to methods of predicting whether a child will develop allergies, and ways to prevent them from developing at all.
Published Titanium micro-spikes skewer resistant superbugs
(via sciencedaily.com) Original source A new study suggests rough surfaces inspired by the bacteria-killing spikes on insect wings may be more effective at combating drug-resistant superbugs, including fungus, than previously understood.
Published New species of marine bacteria isolated from a deep-sea cold seep
(via sciencedaily.com) Original source Researchers have isolated a new strain of marine bacteria with unique characteristics from the ocean seabed.
Published How brucellosis -- which can jump from animals to humans -- impacts the brain
(via sciencedaily.com) Original source Brucellosis is a disease, caused by the members of bacterial Brucella family, that mainly infects cattle, goats and sheep, leading to pregnancy loss, which has caused billions of dollars in economic losses for livestock producers worldwide. The disease can also jump from animals to humans, mainly through consumption of unpasteurized dairy products or inhaling the spores from the tissues of infected animals. While the disease can cause arthritis, inflammation of the heart and flu-like symptoms in humans, the bacteria can also enter the brain and cause neurobrucellosis, which can lead to long-term neurological complications, headaches, nausea, disorientation, swelling of the brain and sometimes death. Now, a new study has highlighted the protective power of both innate lymphoid cells and specific signaling proteins, known as interferons, in reducing the harmful neurological effects of Brucella.
Published Resistant E. coli rises despite drop in ciprofloxacin use
(via sciencedaily.com) Original source After a nearly threefold drop in prescriptions for the antibiotic ciprofloxacin between 2015 and 2021, the rates of ciprofloxacin-resistant E. coli bacteria circulating in the community did not decline. In fact, a study of Seattle-area women over age 50 who had not taken any antibiotics for at least a year discovered that the incidence of gut-colonizing ciprofloxacin-resistant E. coli actually increased. About 1 in 5 women in the study were affected. The results are consistent with theoretical models indicating that, once a drug-resistant form of E.coli emerges, it will continue to spread by taking up long-term residence in individuals' gut microbiomes. Antibiotic resistant E. coli in the gut is of concern because the bacteria can enter the urinary tract and cause difficult-to-treat infections, particularly in women. Evidence from studies such as this one may be changing paradigms on how to fight the rise in antibiotic resistance.
Published Division of labor affects the risk of infection
(via sciencedaily.com) Original source An international research team reports that, given the same genetic makeup, individual behavior alone determines whether or not an individual in a social group will contract a disease. Clonal raider ants of the species Ooceraea biroi that forage outside the nest are more likely to be infected by parasitic nematodes than conspecifics in the nest. The research team also observed that diseases in the colony altered the behavior of all ants: sick and healthy ants alike remained in the nest and the division of labor was reduced, affecting the overall social organization in the ant colony.
Published Scientists invent new way to sort cells by type using light
(via sciencedaily.com) Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new approach could offer a label-free, nondestructive way to sort cells for a variety of applications, including microbiology, cancer detection and cell therapy.
Published Tiny magnetic beads produce an optical signal that could be used to quickly detect pathogens
(via sciencedaily.com) Original source Engineers identified an optical signature in a widely used class of magnetic 'Dynabeads' that could be used to quickly detect contaminants in food, water, or the human body.
Published Connections between drinking water quality and increased lung infections in people with cystic fibrosis
(via sciencedaily.com) Original source High levels of some minerals and metals in environmental water supplies may increase the risk of nontuberculous mycobacteria (NTM) pulmonary infections in people with cystic fibrosis, according to a new study. The study found the presence of the metals molybdenum and vanadium along with sulfate -- a collection of mineral salts -- in the U.S. municipal water system was associated with an increased incidence of NTM pulmonary infections, the leading cause of drinking-water associated illnesses.
Published Epigenetic mechanism that causes bitter taste distortion discovered
(via sciencedaily.com) Original source A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.
Published Fungi-eating plants and flies team up for reproduction
(via sciencedaily.com) Original source Fungi-eating orchids were found for the first time to offer their flowers to fungi-eating fruit flies in exchange for pollination, which is the first evidence for nursery pollination in orchids. This unique new plant-animal relationship hints at an evolutionary transition towards mutualistic symbiosis.
Published Could microplastics in soil introduce drug-resistant superbugs to the food supply?
(via sciencedaily.com) Original source A new review argues ever-present microplastics could promote gene transfer among microbes, potentially resulting in greater antibiotic resistance. The review calls for more research on microplastic-microbe interactions where our food is grown.
Published Biologist gets the scoop on squash bug poop
(via sciencedaily.com) Original source A discovery about how a common insect acquires a microbe that is essential for its growth may help in the control of an agricultural pest.
Published Fungus gnats as pollinators not pests
(via sciencedaily.com) Original source Many plants and crops rely on insects to pollinate them so they can reproduce. A new study has shown that several flowering plants from the group Euonymus are pollinated by fungus gnats, a dipteran insect. Specifically, they pollinate Euonymus plants which have red-petaled flowers with short stamens and yogurt-like scent. Although fungus gnats are known to pollinate hundreds of plant species, this study shows that the particular traits of red Euonymus flowers were likely to have been acquired via pollination syndrome, evolving over a process of natural selection to be pollinated specifically by fungus gnats. This research highlights the important role of Diptera, which are commonly regarded as pests, in plant diversity and evolution.
Published New antibiotic from microbial 'dark matter' could be powerful weapon against superbugs
(via sciencedaily.com) Original source A new powerful antibiotic, isolated from bacteria that could not be studied before, seems capable of combating harmful bacteria and even multi-resistant 'superbugs'. Named Clovibactin, the antibiotic appears to kill bacteria in an unusual way, making it more difficult for bacteria to develop any resistance against it.
Published High-fat diets alter gut bacteria, boosting colorectal cancer risk in mice
(via sciencedaily.com) Original source Researchers have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that are modified by those bacteria, predisposing mice to colorectal cancer. The findings bring scientists closer to understanding the causes of and how to prevent colorectal cancer.
Published New antifungal therapy for fungal meningitis
(via sciencedaily.com) Original source A team of researchers successfully tested a new antifungal therapy to treat fungal meningitis.