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Categories: Biology: Microbiology, Engineering: Biometric
Published How bacteria evolve resistance to antibiotics



Bacteria can rapidly evolve resistance to antibiotics by adapting special pumps to flush them out of their cells, according to new research. Antimicrobial resistance is a growing problem of global significance. The rise of resistant 'superbugs' threatens our ability to use antimicrobials like antibiotics to treat and prevent the spread of infections caused by microorganisms. It is hoped that the findings will improve how antibiotics are used to help prevent further spread of antimicrobial resistance.
Published Like ancient mariners, ancestors of Prochlorococcus microbes rode out to sea on exoskeleton particles



Throughout the ocean, billions upon billions of plant-like microbes make up an invisible floating forest. As they drift, the tiny organisms use sunlight to suck up carbon dioxide from the atmosphere. Collectively, these photosynthesizing plankton, or phytoplankton, absorb almost as much CO2 as the world’s terrestrial forests. A measurable fraction of their carbon-capturing muscle comes from Prochlorococcus — an emerald-tinged free-floater that is the most abundant phytoplankton in the oceans today. New research suggests the microbe's ancient coastal ancestors colonized the ocean by rafting out on chitin particles.
Published Nature favors creatures in largest and smallest sizes



Surveying the body sizes of Earth's living organisms, researchers found that the planet's biomass -- the material that makes up all living organisms -- is concentrated in organisms at either end of the size spectrum.
Published How life and geology worked together to forge Earth's nutrient rich crust



Around 500 million years ago life in the oceans rapidly diversified. In the blink of an eye -- at least in geological terms -- life transformed from simple, soft-bodied creatures to complex multicellular organisms with shells and skeletons. Now, research has shown that the diversification of life at this time also led to a drastic change in the chemistry of Earth's crust -- the uppermost layer we walk on and, crucially, the layer which provides many of the nutrients essential to life.
Published A journey to the origins of multicellular life: Long-term experimental evolution in the lab



Over 3,000 generations of laboratory evolution, researchers watched as their model organism, 'snowflake yeast,' began to adapt as multicellular individuals. In new research, the team shows how snowflake yeast evolved to be physically stronger and more than 20,000 times larger than their ancestor. Their study is the first major report on the ongoing Multicellularity Long-Term Evolution Experiment (MuLTEE), which the team hopes to run for decades.
Published Fecal microbiota transplants: Two reviews explore what's worked, what hasn't, and where do we go from here



Fecal microbiota transplants are the most effective and affordable treatment for recurrent infections with Clostridioides difficile, an opportunistic bacterium and the most common cause of hospital-acquired intestinal infections. However, attempts to treat chronic noncommunicable diseases such as ulcerative colitis and metabolic syndrome via fecal microbiota transplantation (FMT) have yielded mixed results.
Published Crops evolved by swapping genetic modules between cells



Comparing individual cells across corn, sorghum, and millet reveals evolutionary differences among these important cereal crops, according to a new study. The findings bring researchers closer to pinpointing which genes control important agricultural traits such as drought tolerance, which will help scientists faced with a changing climate adapt crops to drier environments.
Published African rhinos share retroviruses not found in Asian rhinos or other related species



Rhinoceros belong to a mammalian order called odd-toed ungulates that also include horses and tapirs. They are found in Africa and Asia. Until recently, evidence suggested that throughout their evolutionary history, gamma-retroviruses such as Murine leukemia virus had not colonized their genomes, unlike most other mammalian orders. The colonization process is called retroviral endogenization and has resulted in most mammalian genomes being comprised of up to ten percent retroviral like sequences.
Published Beetles and their biodiversity in dead wood



Which energy type promotes the biodiversity of beetles living in dead wood in the forest? That depends entirely on where the beetles are in the food chain.
Published Basic 'toolkit' for organ development is illuminated by sea star



One of the basic and crucial embryonic processes to unfold in virtually every living organism is the formation of hollow, tubular structures that go on to form blood vessels or a digestive tract, and through branching and differentiation, complex organs including the heart and kidneys. This study illuminates fundamental design principles of tubulogenesis for all chordates, including mammals.
Published Scientists create CRISPR-based drug candidate targeting the microbiome



A new drug candidate targeting E. coli in the gut is in phase 1 clinical trials. According to a new paper it may improve the well-being of blood cancer patients and reduce their mortality rate from E. coli infections.
Published Exploring the underground connections between trees



Fungal networks interconnecting trees in a forest is a key factor that determines the nature of forests and their response to climate change. These networks have also been viewed as a means for trees to help their offspring and other tree-friends, according to the increasingly popular 'mother-tree hypothesis'. An international group of researchers re-examined the evidence for and against this hypothesis in a new study.
Published Tuberculosis disease intensifies HIV antibody response in people with HIV



New research found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis.
Published 'Super-resolution' imaging technology



Researchers describe developing a super-resolution imaging platform technology to improve understanding of how nanoparticles interact within cells.
Published Viruses could reshuffle the carbon cycle in a warming world



The roles microbes play in ecosystems are changing with global warming. Microbes are also affected by infection by viruses, but scientists know relatively little about how these viral infections could change how microbes react to warming. In this study, scientists describe different ways that increasing temperatures could affect viruses and their microbial hosts. Their preliminary models show that viruses could alter carbon balance, causing some ecosystems to switch from net carbon sources to net carbon sinks.
Published Scientists develop gene silencing DNA enzyme that can target a single molecule



Researchers have developed a DNA enzyme -- or DNAzyme -- that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough 'gene silencing' technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.
Published Uniformity of prey can yield spider-eat-spider world



A limited menu of prey may weave a tangled food web by emboldening wolf spiders of multiple species to dine on each other and even cannibalize their own, says a new study.
Published An unprecedented view of gene regulation



Using a new technique, researchers have shown that they can map interactions between gene promoters and enhancers with 100 times higher resolution than has previously been possible.
Published Tiny microbes could brew big benefits for green biomanufacturing



Scientists find new route in bacteria to decarbonize industry. The discovery could reduce greenhouse gas emissions from the manufacturing of fuels, drugs, and chemicals. A research team has engineered bacteria to produce new-to-nature carbon products that could provide a powerful route to sustainable biochemicals.
Published Elucidating the mysteries of enzyme evolution at the macromolecular level



Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.