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Categories: Biology: Microbiology, Engineering: Biometric
Published Smart surgical implant coatings provide early failure warning while preventing infection



Newly developed 'smart' coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria, researchers report. The coatings integrate flexible sensors with a nanostructured antibacterial surface inspired by the wings of dragonflies and cicadas.
Published Scientist uncovers roots of antibiotic resistance



Microbiologists have uncovered the evolutionary origins of antimicrobial resistance (AMR) in bacteria. His studies on the bacterium that causes cholera, Vibrio cholerae, provide insight into deciphering what conditions must occur for infectious agents to become resistant. He studied genetic variants of a protein found in bacterial membranes called OmpU. Using computational and molecular approaches, his team found that several OmpU mutations in the cholera bacteria led to resistance to numerous antimicrobial agents. This resistance included antimicrobial peptides that act as defenses in the human gut.
Published Archaea in a warming climate become less diverse, more predictable



Using a long-term multifactor experimental field site researchers showed that experimental warming of a tallgrass prairie ecosystem significantly altered the community structure of soil archaea and reduced their taxonomic and phylogenetic diversity.
Published AI could run a million microbial experiments per year



Automation uncovers combinations of amino acids that feed two bacterial species and could tell us much more about the 90% of bacteria that humans have hardly studied. An artificial intelligence system enables robots to conduct autonomous scientific experiments -- as many as 10,000 per day -- potentially driving a drastic leap forward in the pace of discovery in areas from medicine to agriculture to environmental science.
Published Gutless marine worms on a Mediterranean diet: Animals can synthesize phytosterols



Phytosterols are good for your health, but humans and other animals are not able to make them themselves, only plants can. To acquire phytosterols, humans are increasingly turning to supplements, green smoothies, or a Mediterranean diet with plenty of plant-based foods. Researchers have now discovered that tiny gutless worms from the Mediterranean can synthesize phytosterols on their own. Their study provides evidence that many other animals also have the genes needed to make their own phytosterols.
Published Marine seagrass meadows show resilience to 'bounce back' after die-offs



A study in Florida Bay, one of the largest global contiguous seagrass systems, examined if a phytotoxin that accumulates as seagrass ecosystems become more enriched in nutrients prevents a marine seagrass, turtlegrass, from recruiting into open bare sediment following die-off events. While they do 'bounce back,' long-term monitoring indicates the timeframe for recovery after major die-off events is at least a decade. Turtlegrass can successfully recruit into open bare sediment following die-off events due to biomass partitioning.
Published 'Devastating' fungal infections wiping out crops and threatening global food security, experts warn



Worldwide, growers lose between 10 and 23 per cent of their crops to fungal infection each year, despite widespread use of antifungals. An additional 10-20 per cent is lost post harvest. In a commentary in Nature, academics predict those figures will worsen as global warming means fungal infections are steadily moving polewards, meaning more countries are likely to see a higher prevalence of fungal infections damaging harvests.
Published Predict what a mouse sees by decoding brain signals



A research team has developed a novel machine-learning algorithm that can reveal the hidden structure in data recorded from the brain, predicting complex information such as what mice see.
Published Chances of eliminating HIV infection increased by novel dual gene-editing approach



Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts



Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Wiggly proteins guard the genome



Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Researchers discover that the ice cap is teeming with microorganisms



Greenlandic ice is teeming with life, both on the surface and underneath. There are microscopic organisms that until recently science had no idea existed. There is even evidence to suggest that the tiny creatures color the ice and make it melt faster.
Published Herpes study adds to understanding of viral reinfections, how to potentially prevent them



A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
Published Machine learning helps scientists identify the environmental preferences of microbes



A machine-learning approach can give scientists insight into the environmental preferences of microbes, based only on their genes. The approach has practical research implications: it could help researchers more efficiently grow bacteria in the laboratory. It could also lead to smarter use of microbes in agriculture, ecological restoration, and even probiotics.
Published Mushrooms and their post-rain, electrical conversations



Certain types of fungi can communicate with each other via electrical signals. But much remains unknown about how and when they do so. A group of researchers recently headed to the forest to measure the electrical signals of Laccaria bicolor mushrooms, finding that their electrical signals increased following rainfall.
Published Scientists identify antivirals that could combat emerging infectious diseases



A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published New test reveals existing antibiotics, hiding in plain sight on pharmacy shelves, can treat superbugs



A new test revealed that FDA-approved antibiotics -- available at your neighborhood pharmacy -- can effectively treat superbugs. They are not prescribed, however, because the gold-standard test predicts they will not work. The new test may improve the way antibiotics are developed, tested and prescribed -- and it is openly available to all.
Published Scientists slow aging by engineering longevity in cells



Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting



CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human



What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.