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Categories: Biology: Microbiology, Engineering: Biometric
Published Study shows role of fathers in seeding the microbiota of newborns and confirms benefits of maternal fecal microbiota transplants
(via sciencedaily.com) Original source A mother's contribution to the makeup of a newborn baby's microbiota has been well documented. Now a new article shows the important contributions that fathers make to the composition of microorganisms colonizing a baby's gut as well. Furthermore, the study confirmed that maternal fecal microbiota transfer (FMT) in babies born by caesarean section can help to correct the microbiota disturbances often observed in babies who are not born vaginally.
Published New technique reveals earliest signs of genetic mutations
(via sciencedaily.com) Original source Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.
Published Origin and spread of malaria
(via sciencedaily.com) Original source Researchers have reconstructed the evolutionary history and global spread of malaria over the past 5,500 years, identifying trade, warfare, and colonialism as major catalysts for its dispersal.
Published Scientists engineer yellow-seeded camelina with high oil output
(via sciencedaily.com) Original source Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates 21.4% more oil than ordinary camelina.
Published Soil bacteria respire more CO2 after sugar-free meals
(via sciencedaily.com) Original source Researchers tracked how plant matter moves through bacteria's metabolism. Microbes respire three times as much carbon dioxide (CO2) from non-sugar carbons from lignin compared to sugar from cellulose. Although microbes consume both types of plant matter at the same time, each type enters a different metabolic pathway. Findings could improve predictions of how climate-dependent changes in soil carbon types will affect microbial CO2 production.
Published Virus-like nanoparticles control the multicellular organization and reproduction of host bacteria
(via sciencedaily.com) Original source Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.
Published Scientists unlock secrets of how archaea, the third domain of life, makes energy
(via sciencedaily.com) Original source An international scientific team has redefined our understanding of archaea, a microbial ancestor to humans from two billion years ago, by showing how they use hydrogen gas. The findings explain how these tiny lifeforms make energy by consuming and producing hydrogen. This simple but dependable strategy has allowed them to thrive in some of Earth's most hostile environments for billions of years.
Published New insights on polymicrobial infections in chronic lung diseases
(via sciencedaily.com) Original source Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment.
Published New discovery reveals unexpected ocean algae help cool Earth
(via sciencedaily.com) Original source A common type of ocean algae plays a significant role in producing a massively abundant compound that helps cool the Earth's climate, new research has discovered.
Published Breakthrough in creating cyclic peptide opens the way for new antibiotics
(via sciencedaily.com) Original source A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.
Published Brain's structure hangs in 'a delicate balance'
(via sciencedaily.com) Original source Researchers examined anatomy of neurons from humans, mice and fruit flies. They discovered that the cellular structure of the brain is at a critical point, poised between two phases. New insights could help design computational models of the brain's complexity.
Published Protein study could help researchers develop new antibiotics
(via sciencedaily.com) Original source A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.
Published How human derived RNA fragments help the Hepatitis E virus
(via sciencedaily.com) Original source Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Lung organoids unveil secret: How pathogens infect human lung tissue
(via sciencedaily.com) Original source How do pathogens invade the lungs? Using human lung microtissues, a team has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs' line of defense.
Published Gut microbes from aged mice induce inflammation in young mice, study finds
(via sciencedaily.com) Original source When scientists transplanted the gut microbes of aged mice into young 'germ-free' mice -- raised to have no gut microbes of their own -- the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans. Young germ-free mice transplanted with microbes from other young mice had no such increase.
Published Bartonella DNA Found in Blood of Patients With Psychosis
(via sciencedaily.com) Original source A new study has found that patients diagnosed with schizophrenia or another psychotic disorder are three times more likely to have Bartonella DNA in their blood than adults without these disorders. The work further supports the idea that pathogens -- particularly vector-borne pathogens -- could play a role in mental illness.
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time
(via sciencedaily.com) Original source Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease
(via sciencedaily.com) Original source By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.
Published Mushroom stump waste could be inexpensive, healthy chicken feed supplement
(via sciencedaily.com) Original source Feed costs for producing broiler chickens accounts for 60% to 70% of total production costs, and stump waste from the production of button mushrooms comprises nearly 30% of total mushroom weight. Marrying the two has the potential to reduce both cost and waste, especially in Pennsylvania, which is a national leader in the production of broiler chickens and button mushrooms.
Published Silkworms help grow better organ-like tissues in labs
(via sciencedaily.com) Original source Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.