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Categories: Biology: Microbiology, Engineering: Biometric
Published How seaweed became multicellular



A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.
Published Microbial food as a strategy food production of the future



Scientists have summarized microbial food production strategies.
Published Innovative antiviral defense with new CRISPR tool



The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published PFAS exposure from high seafood diets may be underestimated



A study suggests that people with diets high in seafood may face a greater risk of exposure to PFAS -- the family of human-made toxins known as 'forever chemicals' -- than previously thought. The researchers stress the need for more stringent public health guidelines that establish how much seafood people can safely consume to limit their exposure, particularly in coastal areas where seafood is frequently eaten.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle



Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published New approach for combating 'resting' bacteria



Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.
Published Tropical coral-infecting parasites discovered in cold marine ecosystems



Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research.
Published Genetic underpinnings of environmental stress identified in model plant



Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.
Published Size of salty snack influences eating behavior that determines amount consumed



The size of an individual snack piece not only influences how fast a person eats it, but also how much of it they eat, according to a new study. With nearly a quarter of daily calorie intake in the United States coming from snacks, these findings may have implications for helping people better understand how eating behavior impacts calorie and sodium intake.
Published New drug prevents flu-related inflammation and lung damage



Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Published Scientists identify pro-aging 'sugar signature' in the blood of people living with HIV



Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.
Published Cockayne syndrome: New insights into cellular DNA repair mechanism



Researchers decode repair mechanism during transcription of genetic information.
Published Cold-affinity algae species are gradually being replaced by warm-affinity ones off the coast of Biscay



A study has analyzed the impact of the rise in sea surface temperature on macroalgae communities over the last four decades. Points at various depths were investigated in a location off the coast of Biscay, and an increasing scarcity was observed in the number of cold-affinity structuring species, while small warm-affinity ones have proliferated. The researchers are warning that some ecological functions are in jeopardy as a result.
Published A microbial plastic factory for high-quality green plastic



Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.
Published Machine learning method reveals chromosome locations in individual cell nucleus



Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Do some mysterious bones belong to gigantic ichthyosaurs?



Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.
Published Bacteria in cancer unmasked



Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.
Published New diagnostic tool achieves accuracy of PCR tests with faster and simpler nanopore system



A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.
Published Different means to the same end: How a worm protects its chromosomes



Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Scientists discover new phage resistance mechanism in phage-bacterial arms race



Scientists describe a new mechanism impacting the phage-bacterial arms race, a nanosized epibiotic parasite, TM7x, which helps its host bacterium (a Schaalia odontolytica strain called XH001) achieve resistance to lytic phages.