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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology
Published

Scientists grow 'mini kidneys,' revealing new insights into metabolic defects and potential therapy for polycystic kidney disease      (via sciencedaily.com)     Original source 

Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.

Biology: Biochemistry Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bringing multidrug-resistant pathogens to their knees      (via sciencedaily.com)     Original source 

Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry
Published

How mosquito larva guts could help create highly specific insecticides      (via sciencedaily.com)     Original source 

Did you know that the world's deadliest animal is the mosquito? And Aedes aegypti is one of the most dangerous. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research reports new molecules that label proteins in the unique, alkaline environment of the Ae. aegypti digestive system that could help scientists develop insecticides to fight back.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Ecology: Trees Environmental: General Geoscience: Geochemistry
Published

Integrated dataset enables genes-to-ecosystems research      (via sciencedaily.com)     Original source 

A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Mathematics: Modeling
Published

Can language models read the genome? This one decoded mRNA to make better vaccines      (via sciencedaily.com)     Original source 

Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Marine Biology: Microbiology Ecology: Extinction Ecology: General Ecology: Research Ecology: Sea Life Environmental: Ecosystems Environmental: Water Geoscience: Geochemistry Geoscience: Severe Weather
Published

eDNA methods give a real-time look at coral reef health      (via sciencedaily.com)     Original source 

The study underscores the crucial role of microbes in maintaining coral reef health, akin to the human gut microbiome. Hurricanes and disease outbreaks affect coral reef water microbial communities, leading to changes that may support further reef decline. Microbial analysis enables prompt assessment of disturbances' impacts on coral reefs, facilitating timely interventions to support reef ecosystems. Environmental DNA (eDNA) analysis offers a noninvasive approach to study coral microbial communities and diagnose reef health.

Biology: Microbiology Chemistry: General
Published

Rapid, simultaneous detection of multiple bacteria achieved with handheld sensor      (via sciencedaily.com)     Original source 

A team has developed a method for simultaneous detection of multiple disease-causing bacterial species within one hour using a handheld device.

Biology: General Biology: Marine Biology: Microbiology Biology: Zoology Ecology: General Ecology: Research Ecology: Sea Life Environmental: Ecosystems Environmental: Water Geoscience: Geochemistry Geoscience: Oceanography
Published

What four decades of canned salmon reveal about marine food webs      (via sciencedaily.com)     Original source 

Researchers have shown that levels of anisakid worms -- a common marine parasite -- rose in two salmon species in the Gulf of Alaska and Bristol Bay over a 42-year period. The team discovered this by studying salmon caught, killed and canned from 1979 to 2021. Since anisakid worms have a complex life cycle involving multiple types of hosts, the researchers interpret their rising numbers as a potential sign of ecosystem recovery, possibly driven by rising numbers of marine mammals thanks to the 1972 Marine Mammal Protection Act.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

New research offers insight into the future understanding of MS and its treatments      (via sciencedaily.com)     Original source 

Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk factor for developing multiple sclerosis (MS). Their findings have implications for future basic research in further understanding the biology of EBV in MS, but also has the potential to be applied in clinical trials that target the virus.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Heat flows the secret to order in prebiotic molecular kitchen      (via sciencedaily.com)     Original source 

Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.

Biology: Biochemistry Biology: Microbiology
Published

Microbial signature of colorectal cancer-associated mutations identified in new study      (via sciencedaily.com)     Original source 

Researchers have connected KRAS mutations in colorectal cancer to microbial signatures in the gut.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New tools reveal how genes work and cells organize      (via sciencedaily.com)     Original source 

Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Geoscience: Environmental Issues Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

Giant phage holds promise as treatment for lung infections      (via sciencedaily.com)     Original source 

Researchers have discovered a new bacterial killer that can target common lung infection caused by Burkholderia bacteria that has exciting potential for biotechnological applications.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Zoology Ecology: Endangered Species
Published

Discovery could end global amphibian pandemic      (via sciencedaily.com)     Original source 

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New discovery unravels malaria invasion mechanism      (via sciencedaily.com)     Original source 

A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study reveals the role of a sugar called sialic acid in this invasion process. The findings have major implications for malaria vaccine and drug development.

Biology: General Biology: Microbiology
Published

Scientists further our understanding of how a foodborne bacterium can survive in food preparation environments      (via sciencedaily.com)     Original source 

Scientists have discovered that bacterial populations remain stable on factory floor despite cleaning efforts in ready-to-eat food production facilities.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

Scientists link certain gut bacteria to lower heart disease risk      (via sciencedaily.com)     Original source 

Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers has found that microbes in the gut may affect cardiovascular disease as well. The team has identified specific species of bacteria that consume cholesterol in the gut and may help lower cholesterol and heart disease risk in people.

Biology: Microbiology
Published

Infant gut microbes have their own circadian rhythm, and diet has little impact on how the microbiome assembles      (via sciencedaily.com)     Original source 

Infant gut microbiomes oscillate with a circadian rhythm, even when they are cultivated outside of the body. Researchers report that the rhythm is detectable as early as 2 weeks after birth but becomes more pronounced with age. The finding comes from a randomized controlled trial that also showed that diet has less impact on the development and composition of the infant microbiome than previously thought.