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Categories: Biology: Microbiology, Engineering: Biometric
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published AI discovers that not every fingerprint is unique



Engineers have built a new AI that shatters a long-held belief in forensics -- that fingerprints from different fingers of the same person are unique. It turns out they are similar, only we've been comparing fingerprints the wrong way!
Published Iron influences plant immunity and may promote resiliency against climate change



Researchers discovered that plants manage iron deficiency without helping 'bad' bacteria thrive by eliminating the molecular signal for iron deficiency, and that the iron deficiency signaling pathway and the plant immune system are deeply intertwined. Their findings provide a new target for boosting plant resilience in the face of climate change, and offer new insight into plant and animal microbiomes.
Published Largest diversity study of 'magic mushrooms' investigates the evolution of psychoactive psilocybin production



The genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced. Psilocybe arose much earlier than previously thought -- about 65 million years ago -- and the authors found that psilocybin was first synthesized in mushrooms in the genus Psilocybe. Their analysis revealed two distinct gene orders within the gene cluster that produces psilocybin. The two gene patterns correspond to an ancient split in the genus, suggesting two independent acquisitions of psilocybin in its evolutionary history. The study is the first to reveal such a strong evolutionary pattern within the gene sequences underpinning the psychoactive proteins synthesis.
Published With only the pawprints, researchers study elusive bobcat



With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published War on superbugs can't be won, researchers declare



From a wartime spread of antimicrobial resistant disease in Ukraine, to superbugs in China causing 'white lung' pneumonia in children, 2023 brought no shortage of new evidence that antimicrobial resistance (AMR) continues to be a pressing problem globally, and this pattern shows no sign of abating in 2024 unless a radical shift occurs. To truly tackle the issue of AMR, researchers with the Global Strategy Lab (GSL) argue it needs to be understood as a socio-ecological challenge that accepts AMR as a phenomenon stemming from natural evolutionary processes. In other words, the war on bugs can't be won; what's needed is a major change in how people live with it.
Published Researchers discover molecular 'barcode' used by bacteria to secrete toxins



Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
Published Preventing the destruction of Eucalyptus forest plantations: Naturally occurring pathogenic fungi to control the Eucalyptus snout beetle



Scientists have found naturally occurring pathogenic fungi infecting the Eucalyptus snout beetle in Eucalyptus forest plantations, and characterized them to develop a bio-pesticide for controlling the beetle.
Published Researchers develop algorithm to determine how cellular 'neighborhoods' function in tissues



Researchers have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.
Published Important membrane transport mechanism in pathogenic bacteria



Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.
Published Evolution is not as random as previously thought



A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical accidents.
Published A new approach can address antibiotic resistance to Mycobacterium abscessus



Scientists have created analogs of the antibiotic spectinomycin that are significantly more effective against these highly resistant bacteria.
Published Classifying the natural history of asymptomatic malaria



The dynamic lifecycle of the malaria parasite means that the density of the Plasmodium can suddenly drop below the level of detection in asymptomatic people -- especially when older, less sensitive tests are used. Such fluctuations can make it difficult, when testing only at a single point in time, to determine if an apparently healthy person is in fact infected.
Published Scientists engineer plant microbiome to protect crops against disease



Scientists have engineered the microbiome of plants for the first time, boosting the prevalence of 'good' bacteria that protect the plant from disease. The findings could substantially reduce the need for environmentally destructive pesticides.
Published New roles for autophagy genes in cellular waste management and aging



Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.
Published The surprisingly resourceful ways bacteria thrive in the human gut



New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.
Published Scientists solve mystery of how predatory bacteria recognizes prey



A decades-old mystery of how natural antimicrobial predatory bacteria are able to recognize and kill other bacteria may have been solved, according to new research.
Published Treating tuberculosis when antibiotics no longer work



A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics.