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Categories: Biology: Microbiology, Engineering: Biometric
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Gut bacteria of malnourished children benefit from key elements in therapeutic food
(via sciencedaily.com) Original source New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children's underdeveloped gut microbiomes. The study also has identified the important bacterial strains that process these biochemical components. The findings may help guide treatment with a current food formulation and enable creation of new, more effective formulations in the future.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Nanoprobe with a barcode
(via sciencedaily.com) Original source Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Infection with stomach bacteria may increase risk of Alzheimer's disease
(via sciencedaily.com) Original source Infection with the stomach bacterium Helicobacter pylori could increase the risk of developing Alzheimer's disease: In people over the age of 50, the risk following a symptomatic infection can be an average of 11 percent higher, and even more about ten years after the infection, at 24 percent greater risk.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published A rare enzyme role change with bacterial defense system assembly
(via sciencedaily.com) Original source Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published Fat flies live longer on a diet at any age
(via sciencedaily.com) Original source Putting even elderly, obese flies on a restricted calorie diet extends their lifespan markedly, suggesting obese humans might get similar benefits from cutting calories, even at advanced age.
Published Underwater architects: The 'burrowing effect' of foraminifera on marine environments
(via sciencedaily.com) Original source Impact of single-cell organisms on sediment oxygen levels and bacterial diversity measured for the first time.
Published A new mechanism by which rotavirus makes you sick
(via sciencedaily.com) Original source Scientists report a new mechanism by which rotavirus induces diarrhea by interfering with the normal absorption of nutrients in the intestine.
Published Nature and animal emojis don't accurately represent natural biodiversity
(via sciencedaily.com) Original source The current emoji library doesn't accurately represent the 'tree of life' and the breadth of biodiversity seen in nature according to a new analysis. A team of conservation biologists categorized emojis related to nature and animals and mapped them onto the phylogenetic tree of life. They found that animals are well represented by the current emoji catalog, whereas plants, fungi, and microorganisms are poorly represented. Within the animal kingdom, vertebrates were over-represented while arthropods were underrepresented with respect to their actual biodiversity.
Published Zika's shape-shifting machinery, and a possible vulnerability
(via sciencedaily.com) Original source Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the virus does so much with so little and may have identified a therapeutic vulnerability.
Published How immune cells recognize their enemies
(via sciencedaily.com) Original source In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams a have identified new details in this process.
Published New genes can arise from nothing
(via sciencedaily.com) Original source The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.
Published Molecular fossils shed light on ancient life
(via sciencedaily.com) Original source Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. New research combines geology and genetics, showing how changes in the early Earth prompted a shift in how animals eat.
Published Manipulation of gut microbiota with flaxseed could reduce breast cancer risk
(via sciencedaily.com) Original source A new study demonstrates that the human gut microbiome may be a factor in breast health.
Published Growing biofilms actively alter host environment
(via sciencedaily.com) Original source Dental plaque, gut bacteria and the slippery sheen on river rocks are all examples of biofilms, organized communities of microorganisms that colonize our bodies and the world around us. A new study reveals exactly how growing biofilms shape their environments and fine-tune their internal architecture to fit their surroundings. The findings may have implications for a wide variety of applications, from fighting disease to engineering new types of living active materials.
Published Tiny llama nanobodies neutralize different noroviruses: Can they improve human anti-viral therapies?
(via sciencedaily.com) Original source Researchers investigated a novel strategy to neutralize human noroviruses. They tested the ability of tiny antibodies produced by llamas, called nanobodies, to effectively neutralize human norovirus infection in the lab. The unexpected findings reveal that nanobodies could be developed as a therapeutic agent against human norovirus.
Published Fungus-fighting protein could help overcome severe autoimmune disease and cancer
(via sciencedaily.com) Original source A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research has found. The discovery could pave the way for new and more effective drugs, without the nasty side effects of existing treatments. In addition to helping to manage severe autoimmune conditions, the breakthrough could also help treat all types of cancer.