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Categories: Biology: Microbiology, Engineering: Biometric
Published Viral impostors: Breakthrough for virus research
(via sciencedaily.com) Original source The penetration of viruses into cells can now be tracked with unprecedented accuracy thanks to an innovative design for pseudoviruses.
Published New antibiotic approach proves promising against lyme bacterium
(via sciencedaily.com) Original source Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
(via sciencedaily.com) Original source Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Female sex determining gene identified in mice
(via sciencedaily.com) Original source Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits
(via sciencedaily.com) Original source Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.
Published Observation of a virus attaching to another virus
(via sciencedaily.com) Original source 'Satellite' viruses must be in proximity to their 'helper' virus to replicate, but this research reports the first documented case of a satellite virus attaching itself to its helper virus. Out of 50 observed helpers, 40 had a satellite bound. Bioinformatic analysis of the satellite and helper viruses' genomes provides clues as to why the satellite may have evolved to attach to the helper, and suggests this pair may have been co-evolving for about 100 million years.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells
(via sciencedaily.com) Original source In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New antibodies neutralize resistant bacteria
(via sciencedaily.com) Original source Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future.
Published Investigators examine shifts in coral microbiome under hypoxia
(via sciencedaily.com) Original source A new study provides the first characterization of the coral microbiome under hypoxia, insufficient oxygen in the water.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans
(via sciencedaily.com) Original source Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere
(via sciencedaily.com) Original source A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published The ringed seals in Ilulissat Icefjord, Greenland are special
(via sciencedaily.com) Original source Local hunters in the Icefjord near Ilulissat have long known about a special ringed seal -- the Kangia seal -- which is significantly larger and has a markedly different fur color and pattern than typical Arctic ringed seals. Now scientific studies have shown that the Kangia ringed seal has been isolated from other ringed seals for a long period of time -- more than 100,000 years.
Published Pinpointing HIV immune response
(via sciencedaily.com) Original source New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected cells while also killing viral infected cells, but only within a narrow time window at the start of a cell's infection.
Published Maternal microbiota can affect fetal development
(via sciencedaily.com) Original source Significant differences in the gene activity of the fetal intestine, brain and placenta were identified, depending on the microbes in the mother's body and the compounds produced by them. The findings indicate that maternal microbes are important to her offspring's development and health.
Published New Nijmegen method reveals hidden genetic variations
(via sciencedaily.com) Original source Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Plastic-eating bacteria turn waste into useful starting materials for other products
(via sciencedaily.com) Original source Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published Antibiotics for common childhood infections no longer effective
(via sciencedaily.com) Original source Alarmingly high rates of bacterial resistance to commonly prescribed antibiotics used to treat children and babies has been found in the Asia-Pacific.
Published Risk of viral airborne transmission peaks within 5 seconds of face-to-face encounters
(via sciencedaily.com) Original source Researchers visualized and measured the flow field of aerosol particles derived from exhaled air and examined the risk of viral exposure during face-to-face encounters, such as while walking, jogging, running, or sprinting. The results showed that the number of aerosol particles during face-to-face encounters peaked within 5 seconds after the encounter and rapidly declined thereafter.
Published How cruise ships can steer clear of viral spread
(via sciencedaily.com) Original source Researchers examine how ventilation can affect transmission of airborne viruses in a typical cruise ship cabin based on guidelines developed before and after the pandemic. They conducted simulations for virus droplets from a cough in a typical cabin that accommodates two or more people, with different ventilation rates and different positions of the person emitting the cough. Computational fluid dynamics testing ranged from 1.5 to 15 air changes per hour to capture all possible scenarios, from minimal ventilation to rates exceeding the most recent recommendations.