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Categories: Biology: Microbiology, Engineering: Graphene

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Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.

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Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.

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Synthetic biologists report on a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.

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True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.

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To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.

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Turkana County in northwestern Kenya was thought to be too dry for the mosquitoes that harbor malaria-causing parasites. But that assumption may have been wrong, according to a new study by malaria researchers. The arrival of a new mosquito and a more pernicious species of parasite could reverse the progress East Africa has made in controlling malaria.

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Transition metal dichalcogenide (TMD) semiconductors are special materials that have long fascinated researchers with their unique properties. For one, they are flat, one-atom-thick two-dimensional (2D) materials similar to that of graphene. They are compounds that contain different combinations of the transition metal group (e.g., molybdenum, tungsten) and chalcogen elements (e.g., sulfur, selenium, tellurium).

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The prevalence of malaria infections among migrants from sub-Saharan Africa is considerably high (8%), while Asian and Latin American migrants have a much lower prevalence, according to a new study.

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A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.

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EVEscape predicts future viral mutations, new variants using evolutionary, biological information.  

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A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'  

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DNA analysis of mummified feces reveals two pre-Columbian Caribbean cultures ate a wide variety of plants, like maize, sweet potato, and peanuts -- and tobacco and cotton traces were detected too, according to a new study.

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Scientists have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV. The results showed that, when given intravenously, the only commercially available vaccine against TB successfully and safely prevents lung infection in monkeys infected with the simian, or primate, form of HIV, called SIV. This is despite the vaccine being contraindicated for people living with HIV.

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Can plant-derived nutrients alter gut bacteria to affect brain function? Scientists investigated this question in a study of overweight adults. Their findings suggest that dietary fiber can exert influence on both the composition of gut bacteria and the reward signals in the brain and associated food decision-making.

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New analysis of the remains of victims of the 1918 influenza pandemic, which killed an estimated 50 million people worldwide, contradicts the widespread belief the flu disproportionately impacted healthy young adults. 

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Researchers have developed a 'quantum ruler' to measure and explore the strange properties of multilayered sheets of graphene, a form of carbon. The work may also lead to a new, miniaturized standard for electrical resistance that could calibrate electronic devices directly on the factory floor, eliminating the need to send them to an off-site standards laboratory.   

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Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

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Researchers found that pre-existing immunity to Cytomegalovirus (CMV) can limit its transmission during pregnancy and protect against associated birth defects. The study marks an important step toward the development of a vaccine to protect mothers and their babies against the virus, which is a leading cause of miscarriage and birth defects.

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Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

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Acoels have been found to host a wide diversity of symbiotic, photosynthetic microalgae.