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Categories: Biology: Microbiology, Engineering: Graphene
Published Commonly used antibiotic brings more complications, death in the sickest patients
(via sciencedaily.com) Original source Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure for patients with sepsis, finds a new study.
Published New viruses that could cause epidemics on the horizon
(via sciencedaily.com) Original source Suddenly they appear and -- like the SARS-CoV-2 coronavirus -- can trigger major epidemics: Viruses that nobody had on their radar. They are not really new, but they have changed genetically. In particular, the exchange of genetic material between different virus species can lead to the sudden emergence of threatening pathogens with significantly altered characteristics.
Published How do genetically identical water fleas develop into male or female?
(via sciencedaily.com) Original source Researchers have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a male-female-dependent manner. This study may help further advance technologies in crustacean aquaculture.
Published Plant virus treatment shows promise in fighting metastatic cancers in mice
(via sciencedaily.com) Original source An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus -- a virus that infects black-eyed pea plants -- showed remarkable success in improving survival rates and suppressing the growth of metastatic tumors across various cancer models, including colon, ovarian, melanoma and breast cancer.
Published Cellular activity hints that recycling is in our DNA
(via sciencedaily.com) Original source Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.'
Published Research explores ways to mitigate the environmental toxicity of ubiquitous silver nanoparticles
(via sciencedaily.com) Original source Researchers have taken a key step toward closing the silver nanoparticles knowledge gap with a study that indicates the particles' shape and surface chemistry play key roles in how they affect aquatic ecosystems.
Published New light shed on carboxysomes in key discovery that could boost photosynthesis
(via sciencedaily.com) Original source A research team has discovered how carboxysomes, carbon-fixing structures found in some bacteria and algae, work. The breakthrough could help scientists redesign and repurpose the structures to enable plants to convert sunlight into more energy, paving the way for improved photosynthesis efficiency, potentially increasing the global food supply and mitigating global warming.
Published GPS-like system shows promise as HIV vaccine strategy to elicit critical antibodies
(via sciencedaily.com) Original source A team has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
Published New Rhizobia-diatom symbiosis solves long-standing marine mystery
(via sciencedaily.com) Original source Scientists have discovered a new partnership between a marine diatom and a bacterium that can account for a large share of nitrogen fixation in vast regions of the ocean. The newly-discovered bacterial symbiont is closely related to the nitrogen-fixing Rhizobia which live in partnership with many crop plants and may open up new avenues to engineer nitrogen-fixing plants.
Published New sex-determining mechanism in African butterfly discovered
(via sciencedaily.com) Original source In a study of a species of African butterfly, researchers have discovered a previously undescribed molecular mechanism of how the sex of an embryo is initially specified.
Published 2D all-organic perovskites: potential use in 2D electronics
(via sciencedaily.com) Original source Perovskites are among the most researched topics in materials science. Recently, a research team has solved an age-old challenge to synthesize all-organic two-dimensional perovskites, extending the field into the exciting realm of 2D materials. This breakthrough opens up a new field of 2D all-organic perovskites, which holds promise for both fundamental science and potential applications.
Published An epigenome editing toolkit to dissect the mechanisms of gene regulation
(via sciencedaily.com) Original source A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.
Published New record holder for smallest dispersers of ingested seeds: Woodlice
(via sciencedaily.com) Original source Even bugs as small as woodlice can disperse seeds they eat, setting a new record for smallest animal recorded to do so. The discovery underscores the crucial yet often overlooked role that small invertebrates play in ecosystems.
Published An adjuvant made in yeast could lower vaccine cost and boost availability
(via sciencedaily.com) Original source Adjuvants make vaccines more effective, though one of the best is an expensive extract from the soap bark tree. To lower the cost and avoid the laborious extraction process from bark, synthetic biologists introduced 38 separate genes into yeast to recreate the synthesis of the active molecule, a complex chemical, QS-21, that has a terpene core and numerous sugars. This may be the longest biosynthetic pathway ever inserted into yeast.
Published Marine bacteria team up to produce a vital vitamin
(via sciencedaily.com) Original source Two species of marine bacteria from the North Sea have established an unusual and sometimes destructive relationship to produce the important vitamin B12. The team's experiments show that the two microbial species have developed a coordinated strategy to obtain the scarce but essential vitamin.
Published Limited adaptability makes freshwater bacteria vulnerable to climate change
(via sciencedaily.com) Original source Freshwater bacteria with small genomes frequently undergo prolonged periods of adaptive stagnation. Based on genomic analyses of samples from European lakes, researchers uncovered specific evolutionary strategies that shape these bacteria's lifestyles. Understanding the evolutionary dynamics of aquatic microbial communities is key to safeguarding ecosystem services.
Published Natural compounds that selectively kill parasites
(via sciencedaily.com) Original source An international team has found a family of natural compounds with potential as new and more effective treatments for parasitic worms. The compounds stall the unique metabolic process that worms use to survive in the human gut.
Published Why is breaking down plant material for biofuels so slow?
(via sciencedaily.com) Original source Tracking individual enzymes during the breakdown of cellulose for biofuel production has revealed how several roadblocks slow this process when using plant material that might otherwise go to waste. The research may lead to new ways to improve the breakdown process and make the non-edible parts of plants and other plant waste, such as forestry residue, a more competitive source of biofuels.
Published Bee body mass, pathogens and local climate influence heat tolerance
(via sciencedaily.com) Original source How well bees tolerate temperature extremes could determine their ability to persist in a changing climate. But heat tolerance varies between and within populations, so entomologists examined bee physical traits to understand how these traits interact with environmental conditions, pathogens and other factors.
Published Fruit fly model identifies key regulators behind organ development
(via sciencedaily.com) Original source A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation. An research team developed a fruit fly model to reverse engineer the mechanisms that generate organ tissue.