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Categories: Biology: Microbiology, Engineering: Graphene
Published Progression of herpesvirus infection remodels mitochondrial organization and metabolism
(via sciencedaily.com) Original source Researchers have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to understand the interaction between herpesvirus and host cells. Knowledge can be utilized in the development of viral treatments.
Published Free-forming organelles help plants adapt to climate change
(via sciencedaily.com) Original source Plants' ability to sense light and temperature, and their ability to adapt to climate change, hinges on free-forming structures in their cells whose function was, until now, a mystery. Researchers have now determined how these structures work on a molecular level, as well as where and how they form.
Published Engineers develop innovative microbiome analysis software tools
(via sciencedaily.com) Original source Engineers have developed two new graph-based computational tools for tracking genomic variation within microbiomes.
Published Using advanced genetic techniques, scientists create mice with traits of Tourette disorder
(via sciencedaily.com) Original source In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.
Published New vaccine effective against coronaviruses that haven't even emerged yet
(via sciencedaily.com) Original source Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks -- including ones we don't even know about.
Published Improved nutrition, sanitation linked to beneficial changes in child stress and epigenetic programming
(via sciencedaily.com) Original source A new study provides some of the clearest and most comprehensive evidence to date on what is known about stress physiology and 'epigenetic programming.'
Published Stony coral tissue loss disease is shifting the ecological balance of Caribbean reefs
(via sciencedaily.com) Original source A new study shows stony coral tissue loss disease is causing drastic changes in the Caribbean's population of corals, which is sure to disrupt the delicate balance of the ecosystem and threaten marine biodiversity and coastal economies.
Published Genomes of 'star algae' shed light on origin of plants
(via sciencedaily.com) Original source Land plants cover the surface of our planet and often tower over us. They form complex bodies with multiple organs that consist of a broad range of cell types. Developing this morphological complexity is underpinned by intricate networks of genes, whose coordinated action shapes plant bodies through various molecular mechanisms. All of these magnificent forms burst forth from a one-off evolutionary event: when plants conquered Earth's surface, known as plant terrestrialization.
Published How E. coli get the power to cause urinary tract infections
(via sciencedaily.com) Original source New research examines how the bacteria Escherichia coli, or E. coli -- responsible for most UTIs -- is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.
Published Source of pregnancy complications from infections revealed by placenta map
(via sciencedaily.com) Original source The placenta's response to infections from malaria, toxoplasmosis and listeria has been mapped in high resolution, possibly paving the way for new treatment options.
Published New discovery of a mechanism that controls cell division
(via sciencedaily.com) Original source Researchers have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases.
Published Novel chemical tool for understanding membrane remodeling in the cell
(via sciencedaily.com) Original source Researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell. The findings lead to a deeper understanding of how membrane remodeling works in human cells and future development of new drugs.
Published For microscopic organisms, ocean currents act as 'expressway' to deeper depths
(via sciencedaily.com) Original source Some of the ocean's tiniest organisms get swept into underwater currents that act as a conduit that shuttles them from the sunny surface to deeper, darker depths where they play a huge role in affecting the ocean's chemistry and ecosystem, according to new research.
Published Scientists track 'doubling' in origin of cancer cells
(via sciencedaily.com) Original source Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.
Published Deeper understanding of malaria parasite development unlocks opportunities to block disease spread
(via sciencedaily.com) Original source Natural malaria infections have been genetically analysed at a higher resolution than ever before, giving insights that could help understand and block transmission.
Published Promising new treatment strategy for deadly flu-related brain disorders
(via sciencedaily.com) Original source Researchers have found that a brain disorder associated with flu (influenza-associated encephalopathy, or IAE) can be caused by the influenza virus entering the brain from the blood via endothelial cells. In these cells, the researchers observed viral protein accumulation, suggesting that antivirals targeting viral transcription/translation may be useful treatments for some patients. Given the lack of effective treatments for IAE, this finding will likely improve patient care and reduce IAE-related deaths worldwide.
Published Activation of innate immunity: Important piece of the puzzle identified
(via sciencedaily.com) Original source Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.
Published When good bacteria go bad: New links between bacteremia and probiotic use
(via sciencedaily.com) Original source Researchers discovered a concerning association between bacteremia and probiotic use, particularly with Clostridium butyricum (C. butyricum) MIYAIRI 588. Whole-genome sequencing revealed that all C. butyricum bacteremia strains were probiotic derivatives. Out of 6,576 cases of positive blood cultures, C. butyricum was detected in only five cases, all derived from probiotics. The study underscores rare but serious adverse events linked to probiotics, advocating cautious prescribing practices, especially for hospitalized patients.
Published Medical school scientist creates therapy to kill hypervirulent bacteria
(via sciencedaily.com) Original source Researchers are on a mission to kill drug-resistant bacteria, and a new study has identified a therapy that can penetrate the slime that such infections use to protect themselves from antibiotics.Researchers have shown that an antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae. The bacteria, commonly found in the intestines, is usually harmless. It becomes a health hazard when it enters other parts of the body and can cause pneumonia, urinary tract and wound infections. Those at highest risk include seniors and patients with other health problems such as diabetes, cancer, kidney failure and liver disease.
Published Therapy to kill hypervirulent bacteria developed
(via sciencedaily.com) Original source A study has identified a therapy that can penetrate the slime that such infections use to protect themselves from antibiotics. Scientists showed that an antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae. The bacteria, commonly found in the intestines, is usually harmless. It becomes a health hazard when it enters other parts of the body and can cause pneumonia, urinary tract and wound infections. Those at highest risk include seniors and patients with other health problems such as diabetes, cancer, kidney failure and liver disease.