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Categories: Biology: Microbiology, Physics: Quantum Computing

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The legendary Alexander Fleming, who famously discovered penicillin, once said 'never to neglect an extraordinary appearance or happening.' And the path of science often leads to just that. New research is turning the page in our understanding of harmful bacteria and how they turn on certain genes, causing disease in our bodies.

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Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.

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A bacterium found in the sea can degrade a plastic that otherwise resists microbial breakdown in marine environments.

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A research team has discovered a fundamental mechanism that helps the dreaded hospital pathogen Acinetobacter baumannii to survive. This mechanism explains why the pathogen is difficult to eradicate in hospitals and why infections flare up again and again in patients: When living conditions become too unfavorable for the bacteria, they fall into a kind of slumber. In this state, conventional diagnostic methods can no longer detect them nor is it possible to kill them off. When living conditions improve again, they awaken from this 'deep sleep'.

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When Hurricane Ian struck southwest Florida in September 2022, it unleashed a variety of Vibrio bacteria that can cause illness and death in humans, according to a new study.

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The heat shock response of cells is a classic model of biological adaptation, part of the fundamental processes of life -- conserved in creatures from single-celled yeast to humans -- that allow our cells to adjust to changing conditions in their environment. For years, scientists have focused on how different genes respond to heat stress to understand this survival technique. Now, thanks to the innovative use of advanced imaging techniques, researchers are getting an unprecedented look at the inner machinery of cells to see how they respond to heat stress. 

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One of the building blocks of ocean life can adapt to cope with the effects of climate change, according to new research. The discovery holds promises for biotechnology developments that could counter the negative effects of changing environmental conditions, such as ocean warming and even the reduction in the productivity of crops. 

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Researchers conducted a statewide survey of all patients on breathing machines in hospitals and long-term care facilities and found that a significant percentage of them harbored two pathogens known to be life-threatening in those with compromised immune systems. One pathogen, Acinetobacter baumannii, was identified in nearly 31 percent of all patients on ventilators to assist with their breathing; Candida auris was identified in nearly 7 percent of patients on ventilators, according to the study.

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Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.

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Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.

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Synthetic biologists report on a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.

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True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.

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Physicists have shown that simulating models of hypothetical time travel can solve experimental problems that appear impossible to solve using standard physics.

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To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.

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Turkana County in northwestern Kenya was thought to be too dry for the mosquitoes that harbor malaria-causing parasites. But that assumption may have been wrong, according to a new study by malaria researchers. The arrival of a new mosquito and a more pernicious species of parasite could reverse the progress East Africa has made in controlling malaria.

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The prevalence of malaria infections among migrants from sub-Saharan Africa is considerably high (8%), while Asian and Latin American migrants have a much lower prevalence, according to a new study.

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A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.

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EVEscape predicts future viral mutations, new variants using evolutionary, biological information.  

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A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'  

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DNA analysis of mummified feces reveals two pre-Columbian Caribbean cultures ate a wide variety of plants, like maize, sweet potato, and peanuts -- and tobacco and cotton traces were detected too, according to a new study.