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Categories: Biology: Microbiology, Physics: Optics
Published Translating nuclear waste site data into microbial ecosystem insights



A flagship seven-year study that explores how environmental stresses influence different ecological processes shaping the composition and structure of microbial communities in groundwater has now been published.
Published New potato-threatening pathogens reported for first time in Pennsylvania, US



As the home of many beloved snack companies, Pennsylvania values its potatoes. Tasty tubers across the state may face the threat of newly identified pathogen strains, though, according to researchers who made the finding and aim to develop management strategies.
Published Ancient 'chewing gum' reveals stone age diet



What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.
Published HIV antibodies protect animals in proof-of-concept study



Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. The antibodies -- a human broadly neutralizing antibody and two antibodies isolated from previously vaccinated monkeys -- target the fusion peptide, a site on an HIV surface protein that helps the virus fuse with and enter cells.
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves



Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published The metalens meets the stars



Researchers have developed a 10-centimeter-diameter glass metalens that can image the sun, the moon and distant nebulae with high resolution. It is the first all-glass, large-scale metalens in the visible wavelength that can be mass produced using conventional CMOS fabrication technology.
Published Ultrafast laser pulses could lessen data storage energy needs



A discovery from an experiment with magnetic materials and ultrafast lasers could be a boon to energy-efficient data storage.
Published Study throws our understanding of gene regulation for a loop



To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies



A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Researchers optimize 3D printing of optically active nanostructures



The shape, size and optical properties of 3-dimensional nanostructures can now be simulated in advance before they are produced directly with high precision on a wide variety of surfaces. Nanoprobes or optical tweezers with sizes in the nanometre range are now within reach.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute



Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published New technology for conducting deep-sea research on fragile organisms



Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.
Published Tests can reveal whether an antibody can turn into a killer



A promising antibody failed testing. This is good news for developing a broad-spectrum antidote against the world's most dangerous snake venoms.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity



Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published One-step synthesis of the most common, yet highly intricate, antibiotic molecular scaffold



Researchers have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes the toxicity that is a common feature of similar Fischer-carbene synthetic methodologies, and was used to synthesize the scaffold of the thienamycin antibiotic in high yield. This work is an important advancement in sustainable chemistry that should benefit drug development and other chemical syntheses.
Published Solid-state qubits: Forget about being clean, embrace mess



New findings debunk previous wisdom that solid-state qubits need to be super dilute in an ultra-clean material to achieve long lifetimes. Instead, cram lots of rare-earth ions into a crystal and some will form pairs that act as highly coherent qubits, a new paper shows.
Published The power of pause: Controlled deposition for effective and long-lasting organic devices



In organic optoelectronic devices, the control of molecular deposition on thin films is important for optimal surface arrangement and device performance. In a recent study, researchers developed a new method for achieving stable deposition on thin films effectively. They also developed a tool to track real-time potential changes on the surface. These findings are expected to aid the improvement of organic devices, such as organic light-emitting diodes, in terms of efficacy and durability.
Published Candida evolution disclosed: New insights into fungal infections



Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published Many more infected by TBE virus than previously known



The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed. This has been shown in a new study of Swedish blood donors.