Showing 20 articles starting at article 721
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Categories: Biology: Microbiology, Space: Astronomy
Published Steroid drugs used for HRT can combat E. coli and MRSA
(via sciencedaily.com) Original source Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Who knew that coprophagy was so vital for birds' survival?
(via sciencedaily.com) Original source New research explains how eating feces (known as coprophagy) shapes wild birds' digestive tracts (gut biota), enabling them to absorb lost or deficient nutrients and adjust to seasonal variations in food sources.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Maternal obesity may promote liver cancer
(via sciencedaily.com) Original source Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern. It not only affects the health of those who suffer from it, but could also have serious consequences for their offspring. Scientists have studied the impact of maternal obesity on the risk of developing liver disease and liver cancer. Using an animal model, the team discovered that this risk was indeed much higher in the offspring of mothers suffering from obesity.
Published Peering into the tendrils of NGC 604 with NASA's Webb
(via sciencedaily.com) Original source The formation of stars and the chaotic environments they inhabit is one of the most well-studied, but also mystery-shrouded, areas of cosmic investigation. The intricacies of these processes are now being unveiled like never before by NASA's James Webb Space Telescope.
Published Researchers uncover protein responsible for cold sensation
(via sciencedaily.com) Original source Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.
Published Nasa’s Webb, Hubble telescopes affirm universe’s expansion rate, puzzle persists
(via sciencedaily.com) Original source When you are trying to solve one of the biggest conundrums in cosmology, you should triple check your homework. The puzzle, called the 'Hubble Tension,' is that the current rate of the expansion of the universe is faster than what astronomers expect it to be, based on the universe's initial conditions and our present understanding of the universe's evolution.
Published 'Molecular Rosetta Stone' reveals how our microbiome talks to us
(via sciencedaily.com) Original source Researchers have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.
Published Higher bacterial counts detected in single-serving milks, researchers report
(via sciencedaily.com) Original source Scientists have detected higher bacterial counts in commercial, paperboard single-serving containers two weeks after processing than milk packaged in larger containers from the same facilities.
Published New study discovers how altered protein folding drives multicellular evolution
(via sciencedaily.com) Original source Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.
Published Researchers develop artificial building blocks of life
(via sciencedaily.com) Original source For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Published Researchers open new leads in anti-HIV drug development, using a compound found in nature
(via sciencedaily.com) Original source A team of researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
Published How does a virus hijack insect sperm to control disease vectors and pests?
(via sciencedaily.com) Original source A widespread bacteria called Wolbachia and a virus that it carries can cause sterility in male insects by hijacking their sperm, preventing them from fertilizing eggs of females that do not have the same combination of bacteria and virus. A new study has uncovered how this microbial combination manipulates sperm, which could lead to refined techniques to control populations of agricultural pests and insects that carry diseases like Zika and dengue to humans.
Published The Malaria parasite generates genetic diversity using an evolutionary 'copy-paste' tactic
(via sciencedaily.com) Original source All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.
Published First atom-level structure of packaged viral genome reveals new properties, dynamics
(via sciencedaily.com) Original source A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets researchers report.
Published Children surpass a year of HIV remission after treatment pause
(via sciencedaily.com) Original source Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to new research. The children, who acquired HIV before birth, were enrolled in a clinical trial in which an ART regimen was started within 48 hours of birth and then closely monitored for drug safety and HIV viral suppression. The outcomes reported today follow planned ART interruptions once the children met predefined virological and immunological criteria.