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Categories: Biology: Microbiology, Mathematics: Modeling
Published Large language models don't behave like people, even though we may expect them to



People generalize to form beliefs about a large language model's performance based on what they've seen from past interactions. When an LLM is misaligned with a person's beliefs, even an extremely capable model may fail unexpectedly when deployed in a real-world situation.
Published Biosensor reveals gibberellin's critical role in legume nitrogen-fixation -- paving the way for self-fertilizing cereals



Researchers demonstrate that the plant hormone gibberellin (GA) is essential for the formation and maturation of nitrogen-fixing root nodules in legumes and can also increase nodule size.
Published Dual action antibiotic could make bacterial resistance nearly impossible



New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.
Published Pioneering the cellular frontier



Scientists use a multimodal approach that combines hard X-ray computed tomography and X-ray fluorescence imaging to see the structure and chemical processes inside of a single cell.
Published New rapid method for determining virus infectivity



A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.
Published Risks and benefits of integrating AI into medical decision-making



Researchers found that an artificial intelligence (AI) model solved medical quiz questions -- designed to test health professionals' ability to diagnose patients based on clinical images and a brief text summary -- with high accuracy. However, physician-graders found the AI model made mistakes when describing images and explaining how its decision-making led to the correct answer.
Published There is mathematical proof in the pudding



In blockchain development, there is a rule of thumb that only two of scalability, security, and decentralization are valid simultaneously. However, the mathematical expression of that rule was still a work in progress. Researchers discovered a mathematical expression for the blockchain trilemma. In the formula for Proof of Work-based blockchains, including Bitcoin, the product of the three terms--scalability, security, and decentralization--is 1.
Published Exposing dengue's invasion strategies



Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.
Published Are AI-chatbots suitable for hospitals?



Large language models may pass medical exams with flying colors but using them for diagnoses would currently be grossly negligent. Medical chatbots make hasty diagnoses, do not adhere to guidelines, and would put patients' lives at risk. A team has systematically investigated whether this form of artificial intelligence (AI) would be suitable for everyday clinical practice. Despite the current shortcomings, the researchers see potential in the technology. They have published a method that can be used to test the reliability of future medical chatbots.
Published Scientists identify possible new transmission factor in hospital-acquired Klebsiella infections



Scientists have identified a critical factor that may contribute to the spread of hospital-acquired infections (HAIs), shedding light on why these infections are so difficult to combat. Their study reveals that the dangerous multidrug resistant (MDR) pathogen, Klebsiella, thrives under nutrient-deprived polymicrobial community conditions found in hospital environments.
Published Scientists use AI to predict a wildfire's next move



Researchers have developed a new model that combines generative AI and satellite data to accurately forecast wildfire spread.
Published Understanding how a red seaweed reduces methane emissions from cows



New research has implications for addressing a leading contributor to climate warming, methane.
Published Genome study informs restoration of American chestnut tree



Researchers use genomes to help restore the American chestnut population and adjust species breeding to the changing climate.
Published The rhythm led by plants is crucial for symbiosis with nutrient-providing bacteria



Recent research on Lotus japonicus, a model leguminous plant, has unveiled that the interaction between legume roots and rhizobia is characterized by periodic gene expression with a six-hour rhythm. This rhythmic gene expression influences the regions of the root susceptible to rhizobial infection and the distribution of nodules. It was also discovered that the plant hormone cytokinin is crucial for maintaining this gene expression rhythm.
Published Hundreds of new genome sequences fill gaps in the fruit fly tree of life



A multitude of new genomic sequence data fills major gaps in the fruit fly tree of life, researchers report.
Published Small animals acquire genes from bacteria that can produce antibiotics



A group of small, freshwater animals (bdelloid rotifers) protect themselves from infections using antibiotic recipes 'stolen' from bacteria, according to new research. This raises the potential that rotifers are producing novel antimicrobials that may be less toxic to animals, including humans, than those we develop from bacteria and fungi.
Published Analyzing internal world models of humans, animals and AI



Researchers have developed a new formal description of internal world models, thereby enabling interdisciplinary research. Internal world models help to make predictions about new situations based on previous experience and to help find one's bearings. The new formalized view helps to compare world models of humans, animals and AI and to eliminate deficits.
Published Secrets behind viral precision



New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
Published Although tiny, peatland microorganisms have a big impact on climate



Polyphenols are generally toxic to microorganisms. In peatlands, scientists thought microorganisms avoided this toxicity by degrading polyphenols using an oxygen-dependent enzyme, and thus that low-oxygen conditions inhibit microbes' carbon cycling. However, a new study found that Arctic peatland microorganisms used alternative enzymes, with and without oxygen, to break down polyphenols. This suggests carbon stored in these ecosystems is more at risk than previously thought.
Published New antidote for cobra bites discovered



Cobras kill thousands of people a year worldwide and current antivenom treatment is expensive and does not effectively treat the necrosis of the flesh where the bite occurs. Using CRISPR technology, scientists have discovered a commonly available drug can stop the necrosis, potentially saving thousands of lives a year.