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Categories: Biology: Microbiology, Mathematics: Statistics
Published New light shed on circadian rhythms
(via sciencedaily.com) Original source Circadian clocks, which drive circadian rhythms, are entwined with many essential systems in living things including plants, fungi, insects, and even humans. Because of this, disruptions to our circadian clocks are linked to higher disease rates in humans, including certain cancers and autoimmune diseases.
Published New machine learning method can better predict spine surgery outcomes
(via sciencedaily.com) Original source Researchers combine AI and mobile health to predict recovery from lumbar spine surgery.
Published Oral nucleoside antiviral is progressing toward future pandemic preparedness
(via sciencedaily.com) Original source Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.
Published Fungus breaks down ocean plastic
(via sciencedaily.com) Original source A fungus living in the sea can break down the plastic polyethylene, provided it has first been exposed to UV radiation from sunlight. Researchers expect that many more plastic degrading fungi are living in deeper parts of the ocean.
Published Antibodies may aid effort to fight influenza B
(via sciencedaily.com) Original source Researchers have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.
Published Researchers discover 'trojan horse' virus hiding in human parasite
(via sciencedaily.com) Original source An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
(via sciencedaily.com) Original source Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
Published New, modified CRISPR protein can fit inside virus used for gene therapy
(via sciencedaily.com) Original source Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Scientists invent 'living bioelectronics' that can sense and heal skin
(via sciencedaily.com) Original source Reaserchers have created a prototype for what they call 'living bioelectronics': a combination of living cells, gel, and electronics that can integrate with living tissue. Tests in mice found that the devices could continuously monitor and improve psoriasis-like symptoms, without irritating skin.
Published Novel virus identified in zebrafish from the pet trade causes disease in laboratory fish
(via sciencedaily.com) Original source Zebrafish in the pet trade are asymptomatic carriers of previously undescribed microbes, including a novel virus that causes hemorrhaging in infected laboratory fish, researchers report.
Published High groundwater depletion risk in South Korea in 2080s
(via sciencedaily.com) Original source Team utilizes advanced statistical techniques to project the future groundwater depletion risk.
Published Indian Ocean surface temperature could help anticipate dengue outbreaks
(via sciencedaily.com) Original source Although dengue outbreaks cannot be prevented, it is possible to anticipate them. Scientists have recently identified a global climate indicator that may help improve predictions about the magnitude of dengue outbreaks several months in advance. This indicator, which can be used for any world region, is based on temperature fluctuations at the surface of the Indian Ocean. Obtaining reliable long-term predictions could facilitate efforts to tackle this infection, which has been on the rise for several decades and threatens half of the world's population.
Published Antibiotic pollution disrupts the gut microbiome and blocks memory in aquatic snails
(via sciencedaily.com) Original source Antibiotics prevent snails from forming new memories by disrupting their gut microbiome -- the community of beneficial bacteria found in their guts.
Published Researchers expose new symbiosis origin theories, identify experimental systems for plant life
(via sciencedaily.com) Original source Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.
Published hnRNPM, a guardian of the integrity of cellular protein production
(via sciencedaily.com) Original source Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed
(via sciencedaily.com) Original source New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes
(via sciencedaily.com) Original source A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published New antibiotic kills pathogenic bacteria, spares healthy gut microbes
(via sciencedaily.com) Original source Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.
Published New research approach: Exploring the mouthfeel of food with a microscope
(via sciencedaily.com) Original source A new perspectives article focuses on different ways to study the mouthfeel of food using atomic force microscopy to better understand the biophysical mechanisms that contribute to taste sensations in a broader sense. New findings in this area could drive the development of health-promoting products that contain less salt, fat, sugar and calories but still have a convincing mouthfeel.
Published Orchids support seedlings through 'parental nurture' via shared underground fungal networks
(via sciencedaily.com) Original source Orchid plants nurture their seedlings via an underground fungal network, new research has revealed.