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Categories: Biology: Microbiology, Mathematics: Statistics
Published How bacteria recognize viral invasion and activate immune defenses
(via sciencedaily.com) Original source Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Microbes could help reduce the need for chemical fertilizers
(via sciencedaily.com) Original source A new metal-organic coating protects bacterial cells from damage without impeding their growth or function. The coated bacteria, which produce ammonia, could make it much easier for farmers to deploy microbes as fertilizers.
Published Visualizing 'traffic jams' inside living cells
(via sciencedaily.com) Original source Researchers have unveiled a groundbreaking approach to label-free visualization of intracellular cargo trafficking in living cells, achieving high-speed and limitless observation capabilities. By developing a cargo-localization interferometric scattering (CL-iSCAT) microscope, scientists meticulously tracked the intricate movements of numerous cargos in the bustling cellular world. Surprisingly, cells employ human-like strategies to manage their transport challenges.
Published Surveilling wetlands for infectious bird flu -- and finding it
(via sciencedaily.com) Original source Recently, morning omelets and holiday dinners have gotten more expensive. One likely cause is bird flu, outbreaks of which led to the deaths of millions of chickens and turkeys from infection or culling in 2022, according to the U.S. Department of Agriculture, and which still demands rigorous monitoring of wild populations. Now, researchers have developed a method that detected infectious bird flu virus in wetlands frequented by waterfowl.
Published Colliding ribosomes activate RNA repair
(via sciencedaily.com) Original source Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Novel C. diff structures are required for infection, offer new therapeutic targets
(via sciencedaily.com) Original source Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published Dangerous bee virus less deadly in at least one US forest
(via sciencedaily.com) Original source Researchers have found that the deadly deformed wing virus (DMV) in bees may have evolved to be less deadly in at least one U.S. forest. The findings could have implications for preventing or treating the virus in managed colonies, researchers said.
Published Shedding new light on sugars, the 'dark matter' of cellular biology
(via sciencedaily.com) Original source Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer.
Published Forecasting microbiomes for sustainability and health
(via sciencedaily.com) Original source Microbial communities, or microbiomes, are essential for safeguarding human and environmental health through the most widely used biotechnological process on our planet: biological wastewater treatment. However, the process itself is subject to constant changes, difficult to sustain over long periods of time and emits significant amounts of greenhouse gases.
Published Another step toward the HIV-1 vaccine: Dynamics of neutralizing antibodies
(via sciencedaily.com) Original source Longevity of neutralizing antibodies is an essential factor for an effective HIV-1 vaccination.
Published How tiny hinges bend the infection-spreading spikes of a coronavirus
(via sciencedaily.com) Original source Far from being stiff and pointy, a coronavirus's infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk. A new study suggests that disabling those hinges could block infection.
Published Evolution of taste: Early sharks were able to perceive bitter substances
(via sciencedaily.com) Original source New genetic data show that humans and sharks share bitter taste receptors, even though their evolutionary pathways separated nearly 500 million years ago.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life
(via sciencedaily.com) Original source An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight
(via sciencedaily.com) Original source A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published Cycle of fasting and feeding is crucial for healthy aging
(via sciencedaily.com) Original source Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.
Published Forming ice: There's a fungal protein for that
(via sciencedaily.com) Original source New research explores how proteins produced by a common fungus trigger ice nucleation at warm temperatures. The study holds potential implications for improving our understanding of how life affects precipitation and climate.
Published Yucatán's underwater caves host diverse microbial communities
(via sciencedaily.com) Original source With help from an experienced underwater cave-diving team, researchers have constructed the most complete map to date of the microbial communities living in the submerged labyrinths beneath Mexico's Yucatán Peninsula. Researchers found the cave system's microbiome is distinct from the nearby sea, and microbial communities vary between cave systems forming distinct 'neighborhoods.'
Published The mystery of phosphite -- a scientific detective story
(via sciencedaily.com) Original source Biologists have discovered a phosphorus-based bacterial metabolism that is both new and ancient. In a special role: a calculation from the 1980s, a sewage plant, a new bacterial organism, and a remnant from around 2.5 billion years ago.
Published Yeast cells can produce drugs for treatment of psychotic disorders
(via sciencedaily.com) Original source An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
Published Team creates synthetic enzymes to unravel molecular mysteries
(via sciencedaily.com) Original source A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.