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Categories: Biology: Microbiology, Ecology: General
Published Oral nucleoside antiviral is progressing toward future pandemic preparedness



Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.
Published Urgent need for action now for increasing threat from invasive alien species



Urgent action now is needed to tackle the major and growing global issue of invasive alien species, says a team of 88 experts from 47 countries. The paper follows the (IPBES) thematic assessment report on invasive alien species and their control. The experts say co-developing management actions with multiple stakeholders including government and private sector stakeholders, and Indigenous Peoples and local communities will be critical to achieving success in addressing biological invasions.
Published Fungus breaks down ocean plastic



A fungus living in the sea can break down the plastic polyethylene, provided it has first been exposed to UV radiation from sunlight. Researchers expect that many more plastic degrading fungi are living in deeper parts of the ocean.
Published Researchers call for return of Sumas Lake following devastating 2021 floods



A new proposal has emerged in response to the November 2021 floods that swept Sumas Prairie in the Fraser Valley, British Columbia, causing mass evacuations and millions in damages. Instead of rebuilding the dykes to manage water flows and prevent future floods, scientists, along with members of the Sumas First Nation and other research partners, suggest an alternative: let Sumas Lake, which was drained in the early 1920s and converted into the farmland known as Sumas Prairie, return to its natural state. This can be done by buying out properties on the lakebed -- a solution that is projected to cost around $1 billion, less than half of the estimated $2.4 billion cost of repairing the dykes and installing a new pump station.
Published Antibodies may aid effort to fight influenza B



Researchers have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.
Published Researchers discover 'trojan horse' virus hiding in human parasite



An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct



Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
Published New coral disease forecasting system



Research has led to a new tool for forecasting coral disease that could help conservationists step in at the right times with key interventions. Ecological forecasts are critical tools for conserving and managing marine ecosystems, but few forecasting systems can account for the wide range of ecological complexities in near-real-time.
Published People are altering decomposition rates in waterways



Humans may be accelerating the rate at which organic matter decomposes in rivers and streams on a global scale, according to a new study. That could pose a threat to biodiversity in waterways around the world and increase the amount of carbon in Earth's atmosphere, potentially exacerbating climate change. The study is the first to combine a global experiment and predictive modeling to illustrate how human impacts to waterways may contribute to the global climate crisis.
Published New, modified CRISPR protein can fit inside virus used for gene therapy



Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Scientists invent 'living bioelectronics' that can sense and heal skin



Reaserchers have created a prototype for what they call 'living bioelectronics': a combination of living cells, gel, and electronics that can integrate with living tissue. Tests in mice found that the devices could continuously monitor and improve psoriasis-like symptoms, without irritating skin.
Published Novel virus identified in zebrafish from the pet trade causes disease in laboratory fish



Zebrafish in the pet trade are asymptomatic carriers of previously undescribed microbes, including a novel virus that causes hemorrhaging in infected laboratory fish, researchers report.
Published Indian Ocean surface temperature could help anticipate dengue outbreaks



Although dengue outbreaks cannot be prevented, it is possible to anticipate them. Scientists have recently identified a global climate indicator that may help improve predictions about the magnitude of dengue outbreaks several months in advance. This indicator, which can be used for any world region, is based on temperature fluctuations at the surface of the Indian Ocean. Obtaining reliable long-term predictions could facilitate efforts to tackle this infection, which has been on the rise for several decades and threatens half of the world's population.
Published Antibiotic pollution disrupts the gut microbiome and blocks memory in aquatic snails



Antibiotics prevent snails from forming new memories by disrupting their gut microbiome -- the community of beneficial bacteria found in their guts.
Published Researchers expose new symbiosis origin theories, identify experimental systems for plant life



Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.
Published hnRNPM, a guardian of the integrity of cellular protein production



Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed



New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes



A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published New antibiotic kills pathogenic bacteria, spares healthy gut microbes



Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.
Published New research approach: Exploring the mouthfeel of food with a microscope



A new perspectives article focuses on different ways to study the mouthfeel of food using atomic force microscopy to better understand the biophysical mechanisms that contribute to taste sensations in a broader sense. New findings in this area could drive the development of health-promoting products that contain less salt, fat, sugar and calories but still have a convincing mouthfeel.