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Categories: Biology: Microbiology, Ecology: General

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Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.

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Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.

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An enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.

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Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.

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Researchers have come up with a new, more accurate method for detecting in ticks the emerging Powassan virus, which can cause life-threatening neuroinvasive disease, including encephalitis and meningitis.

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While Wyoming is home to some of North America's most abundant populations of pronghorn that have largely been stable in recent years, a new analysis shows that many herds are experiencing long-term declines in fawn production.

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Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.

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An international research team has designed and manufactured a virus-killing surface that could help control disease spread in hospitals, labs and other high-risk environments.

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An international team of 25 scientists has proposed a roadmap for how to prevent the next pandemic by conserving natural areas and promoting biodiversity, thereby providing animals with enough food, safe havens and distance to limit contact and the transfer of pathogens to humans.

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Researchers have developed a novel sensor for the detection of bacteria. It is based on a chip with an innovative surface coating. This ensures that only very specific microorganisms adhere to the sensor -- such as certain pathogens. The larger the number of organisms, the stronger the electric signal generated by the chip. In this way, the sensor is able not only to detect dangerous bacteria with a high level of sensitivity but also to determine their concentration.

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GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process fundamental to interpreting cell types -- with high consistency compared to that of time-consuming manual annotation by human experts of gene information.

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When officials make tough calls on which areas to prioritize for conservation, biodiversity is often their top consideration. But there are several types of diversity, and not all of them overlap perfectly. In a new study, researchers analyzed 20-years' worth of U.S. Forest Service data and show that the simplest measure of diversity is the best predictor of healthy forest growth, providing a roadmap for quickly and efficiently protecting ecological resources.

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Some plant species will 'win' and others will 'lose' as global warming forces them to move uphill, new research shows.

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A team of scientists has developed a novel antibiotic named COE-PNH2 that is capable of combating hard-to-treat mycobacterial lung infections. Such infections, which are notorious for resisting conventional treatment, pose a serious health threat, especially to the elderly and those with underlying conditions.

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Humans pass on more viruses to domestic and wild animals than we catch from them, according to a major new analysis of viral genomes.

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A new study reveals how fire suppression ensures that wildfires will burn under extreme conditions at high severity, exacerbating the impacts of climate change and fuel accumulation.

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Scientists have found a 'tipping point' in the evolution of fungi that throttles their growth and sculpts their shapes. The findings demonstrate how small changes in environmental factors can lead to huge changes in evolutionary outcomes.

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How was complex life able to develop on the inhospitable early Earth? At the beginning there must have been ribonucleic acid (RNA) to carry the first genetic information. To build up complexity in their sequences, these biomolecules need to release water. On the early Earth, which was largely covered in seawater, that was not so easy to do.

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Millions of people are spreading tuberculosis unknowingly - now scientists say they are close to developing a new test that is as simple as the lateral flows used during the Covid pandemic.

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Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.