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Categories: Biology: Microbiology, Biology: Molecular
Published Hundreds of new genome sequences fill gaps in the fruit fly tree of life
(via sciencedaily.com) Original source A multitude of new genomic sequence data fills major gaps in the fruit fly tree of life, researchers report.
Published Small animals acquire genes from bacteria that can produce antibiotics
(via sciencedaily.com) Original source A group of small, freshwater animals (bdelloid rotifers) protect themselves from infections using antibiotic recipes 'stolen' from bacteria, according to new research. This raises the potential that rotifers are producing novel antimicrobials that may be less toxic to animals, including humans, than those we develop from bacteria and fungi.
Published Analyzing internal world models of humans, animals and AI
(via sciencedaily.com) Original source Researchers have developed a new formal description of internal world models, thereby enabling interdisciplinary research. Internal world models help to make predictions about new situations based on previous experience and to help find one's bearings. The new formalized view helps to compare world models of humans, animals and AI and to eliminate deficits.
Published Secrets behind viral precision
(via sciencedaily.com) Original source New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
Published Although tiny, peatland microorganisms have a big impact on climate
(via sciencedaily.com) Original source Polyphenols are generally toxic to microorganisms. In peatlands, scientists thought microorganisms avoided this toxicity by degrading polyphenols using an oxygen-dependent enzyme, and thus that low-oxygen conditions inhibit microbes' carbon cycling. However, a new study found that Arctic peatland microorganisms used alternative enzymes, with and without oxygen, to break down polyphenols. This suggests carbon stored in these ecosystems is more at risk than previously thought.
Published New antidote for cobra bites discovered
(via sciencedaily.com) Original source Cobras kill thousands of people a year worldwide and current antivenom treatment is expensive and does not effectively treat the necrosis of the flesh where the bite occurs. Using CRISPR technology, scientists have discovered a commonly available drug can stop the necrosis, potentially saving thousands of lives a year.
Published Ancient viruses fuel modern-day cancers
(via sciencedaily.com) Original source The human genome is filled with flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago. Scientists used to think they were harmless, but new research shows that, when reawakened, they help cancer survive and thrive.
Published Reef pest feasts on 'sea sawdust'
(via sciencedaily.com) Original source Researchers have uncovered an under the sea phenomenon where coral-destroying crown-of-thorns starfish larvae have been feasting on blue-green algae bacteria known as 'sea sawdust'.
Published Diatom surprise could rewrite the global carbon cycle
(via sciencedaily.com) Original source When it comes to diatoms that live in the ocean, new research suggests that photosynthesis is not the only strategy for accumulating carbon. Instead, these single-celled plankton are also building biomass by feeding directly on organic carbon in wide swaths of the ocean. These new findings could lead to reduced estimates regarding how much carbon dioxide diatoms pull out of the air via photosynthesis, which in turn, could alter our understanding of the global carbon cycle, which is especially relevant given the changing climate.
Published Paleolithic diets are not without risks
(via sciencedaily.com) Original source High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest caution when following these diets.
Published What fat cats on a diet may tell us about obesity in humans
(via sciencedaily.com) Original source Pet cats may be excellent animal models for the study of obesity origins and treatment in humans, a new study of feline gut microbes suggests -- and both species would likely get healthier in the research process, scientists say.
Published Genome recording makes living cells their own historians
(via sciencedaily.com) Original source Genomes can now be used to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft. The method, called ENGRAM, aims to turn cells into their own historians. ENGRAM couples each kind of biological signal or event inside a cell to a symbolic barcode. This new strategy traces and archives the type and timing of biological signals inside the cell by inserting this information into the genome. For example, this record-keeping can track the commands that turn genes on or off.
Published Influenza viruses can use two ways to infect cells
(via sciencedaily.com) Original source Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species -- and potentially jump between animals and humans.
Published Llama nanobodies: A breakthrough in building HIV immunity
(via sciencedaily.com) Original source Biology researchers have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source -- llamas.
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Unique characteristics of previously unexplored protein discovered
(via sciencedaily.com) Original source Research achieves scientific breakthrough in understanding cell division.
Published Immune system in the spotlight
(via sciencedaily.com) Original source Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.
Published Ancient microbes offer clues to how complex life evolved
(via sciencedaily.com) Original source Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.
Published Harnessing big data helps scientists home in on new antimicrobials
(via sciencedaily.com) Original source Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics.
Published E. coli variant may cause antimicrobial resistance in dogs, humans
(via sciencedaily.com) Original source Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.