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Categories: Biology: Microbiology, Biology: Molecular

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Researchers have studied the cell membranes of ctenophores ('comb jellies') and found they had unique lipid structures that allow them to live under intense pressure.

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Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.

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Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.

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Why did multicellularity arise? Solving that mystery may help pinpoint life on other planets and explain the vast diversity and complexity seen on Earth today, from sea sponges to redwoods to human society. A new article shows how specific physical conditions -- especially ocean viscosity and resource deprivation -- during the global glaciation period known as Snowball Earth could have driven eukaryotes to turn multicellular.

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Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.

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Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

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New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture sustainability.

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Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.

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Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.

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Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.

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Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.

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A new study identified biting flies as reservoirs of bacteria that cause bovine mastitis on dairy farms.

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With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments.

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New biologist-designed shelters will help endangered frogs survive the devastating impacts of a deadly fungal disease by regulating their body temperature to fight off infections.

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New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.

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The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.

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Researchers have developed a new method for detecting foodborne pathogens that is faster, cheaper, and more effective than existing methods. Their microfluidic chip uses light to detect multiple types of pathogens simultaneously and is created using 3D printing, making it easy to fabricate in large amounts and modify to target specific pathogens. The researchers hope their technique can improve screening processes and keep contaminated food out of the hands of consumers.

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Nutritionists generally advise everyone to eat more dietary fiber, but a new study suggests that its effects on health can vary from person to person. The findings indicate that recommendations should be tailored to each individual's gut microbiome.

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Research shows that the increasingly popular weight-loss strategy is safe. Intermittent fasting has become an increasingly popular way to lose weight without counting calories. And a large body of research has shown it s safe. Still, several myths about fasting have gained traction.

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Researchers have discovered a salt adaptation mechanism in plants that facilitates chloride removal from the roots and enhancing salinity tolerance. A research team has uncovered a novel mechanism of plant adaptation to salt stress involving the NaCl-induced translocation of a specific chloride channel protein, AtCLCf.