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Categories: Biology: Microbiology, Biology: Molecular
Published How cells boost gene expression
(via sciencedaily.com) Original source The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has now discovered an important function of antisense RNA (asRNA): the researchers found that asRNA acts as a 'superhighway' in cell transport and thus accelerates gene expression.
Published Simple test for flu could improve diagnosis and surveillance
(via sciencedaily.com) Original source Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment. Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. The test uses CRISPR to distinguish between the two main types of seasonal flu, influenza A and B, as well as seasonal flu subtypes H1N1 and H3N2. It can also identify strains that resist antiviral treatment, and with further work, could potentially detect swine and avian flu strains, including H5N1, which is currently infecting cattle.
Published Cannabis use tied to increased risk of severe COVID-19
(via sciencedaily.com) Original source A new study shows that people with COVID-19 who used cannabis were more likely to be hospitalized and require intensive care than those who did not use the drug.
Published How to make aging a 'fairer game' for all wormkind
(via sciencedaily.com) Original source Researchers have discovered a new fundamental mechanism governing the rules of ageing in worms. The researchers were able to manipulate the mechanism through genetic interventions which dramatically extend not just the lifespan of the worms, but also their health-span. In other words, trading weak, frail old age with vigorous golden years -- all without altering their diet, environment or other external factors.
Published Wild chimpanzees seek out medicinal plants to treat illness and injuries
(via sciencedaily.com) Original source Chimpanzees appear to consume plants with medicinal properties to treat their ailments, according to a new study.
Published Wild yeasts from Patagonia could yield new flavors of lagers
(via sciencedaily.com) Original source New strains of yeast for brewing lager beers, created by hybridizing wild strains of yeast from Patagonia with brewer's yeast, can yield novel flavors and aromas, researchers report.
Published Wooden surfaces may have natural antiviral properties
(via sciencedaily.com) Original source Viruses, including the coronavirus that causes COVID-19, can get passed from person to person via contaminated surfaces. But can some surfaces reduce the risk of this type of transmission without the help of household disinfectants? Wood has natural antiviral properties that can reduce the time viruses persist on its surface -- and some species of wood are more effective than others at reducing infectivity.
Published Blessing in disguise: Mycoviruses enhance fungicide effectiveness against plant pathogens
(via sciencedaily.com) Original source Researchers discovered that mycoviruses, or oomycete viruses, can increase the sensitivity of plant pathogenic oomycete to fungicides like metalaxyl. Their findings suggest greater potential for mycoviruses in biocontrol and contributing to sustainable agriculture.
Published How targeted nutrients can fight cancer
(via sciencedaily.com) Original source An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.
Published Where to put head and tail?
(via sciencedaily.com) Original source Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published How the ketogenic diet improves healthspan and memory in aging mice
(via sciencedaily.com) Original source The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice. While uncovering how the high fat, low carbohydrate diet boosts memory in older mice, scientists identified a new molecular signaling pathway that improves synapse function and helps explain the diet's benefit on brain health and aging.
Published Treating the gut-brain connection with B vitamins to treat Parkinson's Disease
(via sciencedaily.com) Original source A study has revealed a link between gut microbiota and Parkinson's disease. The researchers discovered a decrease in bacterial genes related to the synthesis of vitamins B2 and B7. The lack of these genes was associated with reduced intestinal short-chain fatty acids and polyamines, agents that maintain the intestinal barrier and prevent the leakage of toxins into the blood that can then access the brain. Using B vitamin therapy to address these deficiencies may restore the barrier and treat Parkinson's disease.
Published A high-fat diet may fuel anxiety
(via sciencedaily.com) Original source New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.
Published Computable species descriptions: Scientists develop a new computer language to model organismal traits
(via sciencedaily.com) Original source Understanding organismal traits and learning how they evolve and adapt to different environments is crucial for biologists and the battle against biodiversity loss. To be truly efficient, however, the researchers need to use huge amounts of data, including physical traits and DNA. Furthermore, those different data types need to be accurately linked to each other, so that computers and next-age AI technology can correctly process it. Currently, this process of accurate linking is extremely difficult and largely inefficient. To solve this problem, researchers created a brand new computer language called Phenoscript.
Published Previously uncharacterized parasite uncovered in fish worldwide
(via sciencedaily.com) Original source Using genome reconstruction, scientists unveiled a once 'invisible' fish parasite present in many marine fish world-wide that belongs to the apicomplexans, one of the most important groups of parasites at a clinical level. However, it had gone unnoticed in previous studies. The parasite is geographically and taxonomically widespread in fish species around the planet, with implications for commercial fishing and oceanic food webs.
Published When bacteria are buckling
(via sciencedaily.com) Original source Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.
Published A new weapon in the battle against antibiotic resistance: Temperature
(via sciencedaily.com) Original source Scientists have shown in laboratory experiments that an increase in temperature from 37 to 40 degrees Celsius increased the resistance rate for two antimicrobials, while for a third antimicrobial, the higher temperature reduced the resistance rate. If these results can be replicated in human patients, fever control could be a new way to mitigate the emergence of antibiotic resistance.
Published The genetic 'switches' of bone growth
(via sciencedaily.com) Original source In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Infectious H5N1 influenza virus in raw milk rapidly declines with heat treatment
(via sciencedaily.com) Original source The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk.
Published Can engineered plants help make baby formula as nutritious as breast milk?
(via sciencedaily.com) Original source New research may help close the nutrition gap between infant formula and human breast milk. The study shows how plants can be programmed to produce a diverse array of beneficial sugars found in human breast milk. The findings could lead to healthier and more affordable formula for babies, or more nutritious non-dairy plant milk for adults.