Showing 20 articles starting at article 781
< Previous 20 articles Next 20 articles >
Categories: Biology: Microbiology, Space: The Solar System
Published Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
(via sciencedaily.com) Original source About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.
Published High resolution techniques reveal clues in 3.5 billion-year-old biomass
(via sciencedaily.com) Original source To learn about the first organisms on our planet, researchers have to analyze the rocks of the early Earth. These can only be found in a few places on the surface of the Earth. The Pilbara Craton in Western Australia is one of these rare sites: there are rocks there that are around 3.5 billion years old containing traces of the microorganisms that lived at that time. A research team has now found new clues about the formation and composition of this ancient biomass, providing insights into the earliest ecosystems on Earth.
Published Little groundwater recharge in ancient Mars aquifer, according to new models
(via sciencedaily.com) Original source Mars was once a wet world. The geological record of the Red Planet shows evidence for water flowing on the surface -- from river deltas to valleys carved by massive flash floods. But a new study shows that no matter how much rainfall fell on the surface of ancient Mars, very little of it seeped into an aquifer in the planet's southern highlands.
Published Snaking toward a universal antivenom
(via sciencedaily.com) Original source Scientists discovered antibodies that protect against a host of lethal snake venoms.
Published Revealing what makes bacteria life-threatening
(via sciencedaily.com) Original source Researchers have discovered that a mutation in the cellulose making machinery of E. coli bacteria allows them to cause severe disease in people -- 'good' bacteria make cellulose and 'bad' bacteria can't. The mutations stopped the E. coli making the cell-surface carbohydrate cellulose and this led to increased inflammation in the intestinal tract of the host, resulting in a breakdown of the intestinal barrier, so the bacteria could spread through the body. Understanding how bacteria spread from intestinal reservoirs to the rest of the body is important in preventing infections and tackling antibiotic resistance.
Published Kiss-and-tell: A new method for precision delivery of nanoparticles and small molecules to individual cells
(via sciencedaily.com) Original source The delivery of experimental materials to individual cells with exactness and exclusivity has long been an elusive and much sought-after ability in biology. With it comes the promise of deciphering many longstanding secrets of the cell. A research team has now successfully shown how small molecules and single nanoparticles can be applied directly onto the surface of cells. In the study the scientists describe their technique as a ' kiss' (microkiss) -- an easy and cost-effective new method, unlocking new possibilities in single-cell science with a view towards next generation therapeutic applications.
Published Toxic elements found in stranded whales, dolphins over 15 years
(via sciencedaily.com) Original source Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples collected from 90 whales and dolphins stranded in Georgia and Florida from 2007 to 2021.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published 'The future is fungal': New research finds that fungi that live in healthy plants are sensitive to climate change
(via sciencedaily.com) Original source Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
Published Engineering a coating for disease-free produce
(via sciencedaily.com) Original source Texas A&M researchers combine food-grade wax with essential oils to defend produce from bacteria.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders
(via sciencedaily.com) Original source Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments
(via sciencedaily.com) Original source Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control
(via sciencedaily.com) Original source Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.
Published Researchers are using RNA in a new approach to fight HIV
(via sciencedaily.com) Original source A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published Decline in microbial genetic richness in the western Arctic Ocean
(via sciencedaily.com) Original source Researchers analyzed archival samples of bacteria and archaea populations taken from the Beaufort Sea, bordering northwest Canada and Alaska. The samples were collected between 2004 and 2012, a period that included two years -- 2007 and 2012 -- in which the sea ice coverage was historically low. The researchers looked at samples taken from three levels of water: the summer mixed layer, the upper Arctic water below it and the Pacific-origin water at the deepest level. The study examined the microbes' genetic composition using bioinformatics and statistical analysis across the nine-year time span. Using this data, the researchers were able to see how changing environmental conditions were influencing the organisms' structure and function.
Published Bat 'nightclubs' may be the key to solving the next pandemic
(via sciencedaily.com) Original source Researchers are studying how bats can carry deadly viruses, but not develop symptoms. They found that what happens during swarming behavior -- like social gatherings for bats -- may hold the key to understanding their viral tolerance and translate to human health in fighting off diseases like Ebola and COVID-19.
Published Pollinator's death trap turns into nursery
(via sciencedaily.com) Original source In a group of plants that is famous for luring its pollinators into a death trap, one species offers its flowers as a nursery in exchange. The discovery blurs the line between mutualism and parasitism and sheds light on the evolution of complex plant-insect interactions.
Published Eating too much protein is bad for your arteries, and this amino acid is to blame
(via sciencedaily.com) Original source Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.
Published Viruses that can help 'dial up' carbon capture in the sea
(via sciencedaily.com) Original source Armed with a catalog of hundreds of thousands of DNA and RNA virus species in the world's oceans, scientists are now zeroing in on the viruses most likely to combat climate change by helping trap carbon dioxide in seawater or, using similar techniques, different viruses that may prevent methane's escape from thawing Arctic soil.
Published Under pressure -- space exploration in our time
(via sciencedaily.com) Original source A new paradigm is taking shape in the space industry as the countries and entities accessing space continue to grow and diversify. This dynamic landscape creates both competition and potential for scientific collaboration, as well as the challenges and opportunities of progress.