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Categories: Biology: Microbiology, Environmental: Wildfires
Published 'One ring to rule them all': How actin filaments are assembled by formins
(via sciencedaily.com) Original source Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing filament. Furthermore, the scientists elucidated the reasons for the different speeds at which the different formins promote this process.
Published How tardigrades can survive intense radiation
(via sciencedaily.com) Original source Researchers have discovered that tardigrades -- microscopic animals famed for surviving harsh extremes -- have an unusual response to radiation.
Published How blue-green algae manipulate microorganisms
(via sciencedaily.com) Original source A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.
Published Unlocking the 'chain of worms'
(via sciencedaily.com) Original source An international team of scientists has published a single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Published Millions of gamers advance biomedical research
(via sciencedaily.com) Original source 4.5 million gamers around the world have advanced medical science by helping to reconstruct microbial evolutionary histories using a minigame included inside the critically and commercially successful video game, Borderlands 3. Their playing has led to a significantly refined estimate of the relationships of microbes in the human gut. The results of this collaboration will both substantially advance our knowledge of the microbiome and improve on the AI programs that will be used to carry out this work in future.
Published Green-to-red transformation of Euglena gracilis using bonito stock and intense red light
(via sciencedaily.com) Original source Euglena gracilis, often regarded as a 'superfood,' is a promising microalga with many health and nutritional benefits. In a recent study, researchers found an efficient and low-resource approach to trigger a reddening reaction in E. gracilis using red light and a bonito fish-based culture medium. This reaction is a sign of higher and diverse carotenoid content ratio, meaning the proposed method could help turn E. gracilis into an even more nutritious food source.
Published Researchers resolve old mystery of how phages disarm pathogenic bacteria
(via sciencedaily.com) Original source Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise. In response, scientists are elucidating the ways that bacteria-infecting viruses disarm these pathogens and ushering in the possibility of novel treatment methods.
Published Even the simplest marine organisms tend to be individualistic
(via sciencedaily.com) Original source Sport junkie or couch potato? Always on time or often late? The animal kingdom, too, is home to a range of personalities, each with its own lifestyle. Biologists report on a surprising discovery: even simple marine polychaete worms shape their day-to-day lives on the basis of highly individual rhythms. This diversity is of interest not just for the future of species and populations in a changing environment, but also for medicine.
Published Carbon beads help restore healthy gut microbiome and reduce liver disease progression
(via sciencedaily.com) Original source Innovative carbon beads reduce bad bacteria and inflammation in animal models, which are linked to liver cirrhosis and other serious health issues.
Published How seaweed became multicellular
(via sciencedaily.com) Original source A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.
Published Microbial food as a strategy food production of the future
(via sciencedaily.com) Original source Scientists have summarized microbial food production strategies.
Published Innovative antiviral defense with new CRISPR tool
(via sciencedaily.com) Original source The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published PFAS exposure from high seafood diets may be underestimated
(via sciencedaily.com) Original source A study suggests that people with diets high in seafood may face a greater risk of exposure to PFAS -- the family of human-made toxins known as 'forever chemicals' -- than previously thought. The researchers stress the need for more stringent public health guidelines that establish how much seafood people can safely consume to limit their exposure, particularly in coastal areas where seafood is frequently eaten.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle
(via sciencedaily.com) Original source Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published New approach for combating 'resting' bacteria
(via sciencedaily.com) Original source Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.
Published Tropical coral-infecting parasites discovered in cold marine ecosystems
(via sciencedaily.com) Original source Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research.
Published Genetic underpinnings of environmental stress identified in model plant
(via sciencedaily.com) Original source Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.
Published Size of salty snack influences eating behavior that determines amount consumed
(via sciencedaily.com) Original source The size of an individual snack piece not only influences how fast a person eats it, but also how much of it they eat, according to a new study. With nearly a quarter of daily calorie intake in the United States coming from snacks, these findings may have implications for helping people better understand how eating behavior impacts calorie and sodium intake.
Published New drug prevents flu-related inflammation and lung damage
(via sciencedaily.com) Original source Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Published Scientists identify pro-aging 'sugar signature' in the blood of people living with HIV
(via sciencedaily.com) Original source Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.