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Categories: Biology: Microbiology, Environmental: Wildfires
Published Cockayne syndrome: New insights into cellular DNA repair mechanism
(via sciencedaily.com) Original source Researchers decode repair mechanism during transcription of genetic information.
Published Cold-affinity algae species are gradually being replaced by warm-affinity ones off the coast of Biscay
(via sciencedaily.com) Original source A study has analyzed the impact of the rise in sea surface temperature on macroalgae communities over the last four decades. Points at various depths were investigated in a location off the coast of Biscay, and an increasing scarcity was observed in the number of cold-affinity structuring species, while small warm-affinity ones have proliferated. The researchers are warning that some ecological functions are in jeopardy as a result.
Published A microbial plastic factory for high-quality green plastic
(via sciencedaily.com) Original source Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.
Published Machine learning method reveals chromosome locations in individual cell nucleus
(via sciencedaily.com) Original source Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Do some mysterious bones belong to gigantic ichthyosaurs?
(via sciencedaily.com) Original source Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.
Published Bacteria in cancer unmasked
(via sciencedaily.com) Original source Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.
Published New diagnostic tool achieves accuracy of PCR tests with faster and simpler nanopore system
(via sciencedaily.com) Original source A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Scientists discover new phage resistance mechanism in phage-bacterial arms race
(via sciencedaily.com) Original source Scientists describe a new mechanism impacting the phage-bacterial arms race, a nanosized epibiotic parasite, TM7x, which helps its host bacterium (a Schaalia odontolytica strain called XH001) achieve resistance to lytic phages.
Published Scientists grow 'mini kidneys,' revealing new insights into metabolic defects and potential therapy for polycystic kidney disease
(via sciencedaily.com) Original source Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published How mosquito larva guts could help create highly specific insecticides
(via sciencedaily.com) Original source Did you know that the world's deadliest animal is the mosquito? And Aedes aegypti is one of the most dangerous. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research reports new molecules that label proteins in the unique, alkaline environment of the Ae. aegypti digestive system that could help scientists develop insecticides to fight back.
Published Integrated dataset enables genes-to-ecosystems research
(via sciencedaily.com) Original source A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published eDNA methods give a real-time look at coral reef health
(via sciencedaily.com) Original source The study underscores the crucial role of microbes in maintaining coral reef health, akin to the human gut microbiome. Hurricanes and disease outbreaks affect coral reef water microbial communities, leading to changes that may support further reef decline. Microbial analysis enables prompt assessment of disturbances' impacts on coral reefs, facilitating timely interventions to support reef ecosystems. Environmental DNA (eDNA) analysis offers a noninvasive approach to study coral microbial communities and diagnose reef health.
Published Rapid, simultaneous detection of multiple bacteria achieved with handheld sensor
(via sciencedaily.com) Original source A team has developed a method for simultaneous detection of multiple disease-causing bacterial species within one hour using a handheld device.
Published What four decades of canned salmon reveal about marine food webs
(via sciencedaily.com) Original source Researchers have shown that levels of anisakid worms -- a common marine parasite -- rose in two salmon species in the Gulf of Alaska and Bristol Bay over a 42-year period. The team discovered this by studying salmon caught, killed and canned from 1979 to 2021. Since anisakid worms have a complex life cycle involving multiple types of hosts, the researchers interpret their rising numbers as a potential sign of ecosystem recovery, possibly driven by rising numbers of marine mammals thanks to the 1972 Marine Mammal Protection Act.
Published New research offers insight into the future understanding of MS and its treatments
(via sciencedaily.com) Original source Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk factor for developing multiple sclerosis (MS). Their findings have implications for future basic research in further understanding the biology of EBV in MS, but also has the potential to be applied in clinical trials that target the virus.
Published Heat flows the secret to order in prebiotic molecular kitchen
(via sciencedaily.com) Original source Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.
Published Microbial signature of colorectal cancer-associated mutations identified in new study
(via sciencedaily.com) Original source Researchers have connected KRAS mutations in colorectal cancer to microbial signatures in the gut.