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Categories: Biology: Microbiology, Environmental: Water
Published Which strains of tuberculosis are the most infectious?
(via sciencedaily.com) Original source Highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain's natural habitat. The research provides the first controlled evidence that TB strains may evolve with their human hosts, adapting to be more infectious to specific populations. The findings offer new clues for tailoring preventive treatments after exposure to TB based on affinity between strains host populations.
Published Novel nanosensing technique for quality control of viral vectors in gene therapy
(via sciencedaily.com) Original source Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can differentiate between functional and faulty viral vectors at the single-particle level. This convenient and inexpensive technique will hopefully get us one step closer to advancing treatments for genetic disorders.
Published Breakthrough in plant disease: New enzyme could lead to anti-bacterial pesticides
(via sciencedaily.com) Original source Scientists uncover a pivotal enzyme, XccOpgD, and its critical role in synthesizing C G16, a key compound used by Xanthomonas pathogens to enhance their virulence against plants. This breakthrough opens new avenues for developing targeted pesticides that combat plant diseases without harming beneficial organisms. Insights into XccOpgD's enzymatic mechanism and optimal conditions offer promising prospects for sustainable agriculture, bolstering crop resilience and global food security while minimizing environmental impact.
Published Cheese of the future: Consumers open to animal-free alternatives
(via sciencedaily.com) Original source Companies and institutes are currently working on biotechnological processes for the production of 'dairy products' without the use of cows: In so-called precision fermentation, egg and milk proteins are produced with the help of bacteria, yeasts or other fungi. This results in foods such as milk or cheese with a familiar flavor and texture. Supporters hope that this will lead to more sustainable food production, as nutrient-rich proteins can be produced using fewer resources. But will consumers accept such products?
Published Talking about regeneration
(via sciencedaily.com) Original source Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.
Published Warming stops tiny organisms working together
(via sciencedaily.com) Original source Hotter conditions prevent two tiny organisms working together for mutual benefit, new research shows.
Published The next generation of RNA chips
(via sciencedaily.com) Original source An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.
Published Underwater mapping reveals new insights into melting of Antarctica's ice shelves
(via sciencedaily.com) Original source Clues to future sea level rise have been revealed by the first detailed maps of the underside of a floating ice shelf in Antarctica. An international research team deployed an unmanned submersible beneath the Dotson Ice Shelf in West Antarctica.
Published Nasal COVID-19 vaccine halts transmission, animal study finds
(via sciencedaily.com) Original source A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections.
Published Barriers designed to prevent saltwater intrusion may worsen inland flooding
(via sciencedaily.com) Original source Building protection barriers without accounting for potential inland flooding risks from groundwater can eventually worsen the very issues they aim to solve.
Published AI opens door to safe, effective new antibiotics to combat resistant bacteria
(via sciencedaily.com) Original source In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.
Published New principle for treating tuberculosis
(via sciencedaily.com) Original source Researchers have succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. They describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.
Published Green hydrogen: 'Artificial leaf' becomes better under pressure
(via sciencedaily.com) Original source Hydrogen can be produced via the electrolytic splitting of water. One option here is the use of photoelectrodes that convert sunlight into voltage for electrolysis in so called photoelectrochemical cells (PEC cells). A research team has now shown that the efficiency of PEC cells can be significantly increased under pressure.
Published Scientists capture immune cells hidden in nasal passages
(via sciencedaily.com) Original source Scientists uncover 'striking' immune cell populations poised to fight SARS-CoV-2 in upper airway.
Published Gut microbes implicated in bladder cancer
(via sciencedaily.com) Original source Bladder cancer is the tenth most common type of cancer worldwide and is often linked to exposure to harmful chemicals, such as those found in tobacco smoke. A new study shows that the bacteria in our guts may play an important role in bladder cancer development. The scientists showed experimentally that certain gut bacteria can transform a class of carcinogens, often found in cigarette smoke, into related chemicals that accumulate in the bladder and give rise to tumors.
Published New collaborative research generates lessons for more adaptive lake management
(via sciencedaily.com) Original source A professor gathered feedback from 26 Colorado River Basin managers and experts took on water user roles to discuss consuming, banking and trading Colorado River water.
Published Scientists discover entirely new wood type that could be highly efficient at carbon storage
(via sciencedaily.com) Original source Researchers undertaking an evolutionary survey of the microscopic structure of wood from some of the world's most iconic trees and shrubs have discovered an entirely new type of wood.
Published Injury dressings in first-aid kits provide a new technique to reveal shark species after bite incidents
(via sciencedaily.com) Original source Scientists have revealed that injury dressings found in first-aid kits can reliably be used to identify shark species involved in bite incidents by deploying medical gauze to gather DNA samples from aquatic equipment, such as surfboards.
Published Precise genetics: New CRISPR method enables efficient DNA modification
(via sciencedaily.com) Original source A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. This technology could significantly improve research on proteins in living organisms and opens up new possibilities for medical research.
Published What shapes a virus's pandemic potential? SARS-CoV-2 relatives yield clues
(via sciencedaily.com) Original source Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the COVID-19-causing virus, a new study reveals. The findings provide clues as to why some viruses have greater 'pandemic potential' than others and how researchers might go about identifying those that do before they become widespread.