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Categories: Biology: Microbiology, Geoscience: Earth Science

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Review of research to-date suggests vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.

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Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.

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Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

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Life evolved from simple geochemical processes present on the early Earth. However, the details of this transformation remain a mystery. In this study, researchers modeled the emergence of metabolic pathways from simple geochemical precursors and concluded that surprisingly few reactions in the history of metabolism may have been lost to time.

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Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

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Researchers have discovered that bank voles in southern Sweden (Sk ne) carry a virus that can cause hemorrhagic fever in humans. This finding was made more than 500 km south of the previously known range. 'We were surprised that such high proportion of the relatively few voles that we caught were actually carrying a hantavirus that makes people ill', says infection disease doctor. The virus strain discovered in Sk ne appears to be more closely related to strains from Finland and Karelia than to the variants found in northern Sweden and Denmark.

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A team of scientists has used artificial intelligence (AI) to map the activities of seafloor invertebrate animals, such as worms, clams and shrimps, across all the oceans of the world.

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Mice administered raw milk samples from dairy cows infected with H5N1 influenza experienced high virus levels in their respiratory organs and lower virus levels in other vital organs, according to new findings. The results suggest that consumption of raw milk by animals poses a risk for H5N1 infection and raises questions about its potential risk in humans.

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Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.

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Researchers have managed to analyze, simultaneously, several families of antibiotics in vegetables and earthworms. Sampling carried out in various locations has yielded data on the existence of antimicrobial agents and their derivatives in vegetables. In this respect, Vergara stresses the need for further research to address the problem of contamination by this type of medication in the environment.

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In an interdisciplinary study, researchers discovered that symbiotic bacteria communicate with legume plants through specific molecules and that this communication influences which bacteria grow near the plant roots. The findings provide insights into how plants and soil bacteria form beneficial partnerships for nutrient uptake and resilience. These results are a step towards understanding how communication between plants and soil bacteria can lead to specific beneficial associations providing plants with nutrients.

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The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.

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Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

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Chemistry researchers are hoping to spark a green battery revolution by showing that iron instead of cobalt and nickel can be used as a cathode material in lithium-ion batteries.

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Astronomers have discovered a planet between the sizes of Earth and Venus only 40 light-years away.

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Researchers have developed a quantitative real-time PCR-based detection method for the emerging zoonotic organism Escherichia albertii. They found that E. albertii survives in the human intestinal tract for about four weeks at least.

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Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.

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Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

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Southern California's iconic sandy coastlines are vanishing at an alarming rate, and it's a warning sign for coastal communities worldwide, new research suggests.

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.