Showing 20 articles starting at article 1221
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Categories: Biology: Microbiology, Geoscience: Geology
Published An advance in cryo-EM could be a significant boon for research on potential cancer therapies
(via sciencedaily.com) Original source A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.
Published Capturing CO2 with electricity: A microbial enzyme inspires electrochemistry
(via sciencedaily.com) Original source Humanity continuously emits greenhouse gases and thereby worsens global warming. Increasing research efforts go into developing strategies to convert these gases, such as carbon dioxide (CO2), into valuable products. CO2 accumulates dramatically over the years and is chemically very stable, thus challenging to transform. Yet, for billions of years, some microbes have actively captured CO2 using highly efficient enzymes. Scientists have now isolated one of these enzymes. When the enzyme was electronically branched on an electrode, they observed the conversion of CO2 to formate with perfect efficiency. This phenomenon will inspire new CO2-fixation systems because of its remarkable directionality and rates.
Published Sperm swimming is caused by the same patterns that are believed to dictate zebra stripes
(via sciencedaily.com) Original source Patterns of chemical interactions are thought to create patterns in nature such as stripes and spots. This new study shows that the mathematical basis of these patterns also governs how sperm tail moves.
Published Tiny CRISPR tool could help shred viruses
(via sciencedaily.com) Original source Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.
Published Novel bacterial proteins from seafloor shine light on climate and astrobiology
(via sciencedaily.com) Original source Researchers have unveiled a remarkable discovery: the identification of novel bacterial proteins that play a vital role in the formation and stability of methane clathrates, which trap gigatons of greenhouse gas beneath the seafloor. These newfound proteins not only suppress methane clathrate growth as effectively as toxic chemicals used in drilling but also prove to be eco-friendly and scalable. This innovative breakthrough not only promises to enhance environmental safety in natural gas transportation but also sheds light on the potential for similar biomolecules to support life beyond Earth.
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
(via sciencedaily.com) Original source Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes
(via sciencedaily.com) The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.
Published Decreasing biodiversity may promote spread of viruses
(via sciencedaily.com) Original source How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.
Published Exploring the effect of water on seismic wave attenuation in the upper mantle
(via sciencedaily.com) Original source The mechanism facilitating the smooth movement of the oceanic lithosphere over the underlying asthenosphere (upper mantle) remains poorly understood. Recently, researchers from Japan investigated the effect of water on the seismic properties of olivine rocks, finding that water retention in the asthenosphere can induce sharp drops in shear wave velocity. This also explained other seismic changes observed at the lithosphere-asthenosphere boundary. These findings provide invaluable insights into the diverse seismic activities on Earth.
Published Genetically engineering associations between plants and nitrogen-fixing microbes could lessen dependence on synthetic fertilizer
(via sciencedaily.com) Original source Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.
Published Antibiotics can help some bacteria survive for longer
(via sciencedaily.com) Original source Scientists have found a surprising effect of some antibiotics on certain bacteria -- that the drugs can sometimes benefit bacteria, helping them live longer.
Published New research reveals extreme heat likely to wipe out humans and mammals in the distant future
(via sciencedaily.com) Original source A new study shows unprecedented heat is likely to lead to the next mass extinction, akin to when the dinosaurs died out, eliminating nearly all mammals in some 250 million years time.
Published By air, rain and land: How microbes return after a wildfire
(via sciencedaily.com) Ecological disturbances like wildfires disrupt microbial communities. Researchers found that dispersal played a pivotal role in re-establishing surface-level communities.
Published Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors
(via sciencedaily.com) Original source Researchers have made an important finding about Aedes aegypti mosquitoes -- one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.
Published New strategies reduce treatment failure in malaria by up to 81%
(via sciencedaily.com) Original source To slow artemisinin resistance and reduce treatment failures, an international research team investigated various drug policy interventions in Rwanda, where artemisinin resistance was first reported in 2020. Among other strategies, the team found that next-generation interventions such as triple ACTs (TACTs) -- which combine an artemisinin derivative with two partner drugs or which use a sequential course of one ACT formulation, followed by a different ACT formulation -- resulted in treatment failure counts that were at least 81% lower.
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage
(via sciencedaily.com) Original source Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Nanoparticles made from plant viruses could be farmers' new ally in pest control
(via sciencedaily.com) Engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, the researchers created nanoparticles that can deliver pesticide molecules to previously inaccessible depths in the soil. This 'precision farming' approach could potentially minimize environmental toxicity and cut costs for farmers.
Published How climate warming could disrupt a deep-rooted relationship
(via sciencedaily.com) Trees depend on fungi for their well-being. As climate change and global warming cause higher temperatures and amplified drought, little is known about how these important fungi will respond. To investigate this issue, a research team conducted a climate change experiment where they exposed boreal and temperate tree species to warming and drought treatments to better understand how fungi and their tree hosts respond to environmental changes. Their findings revealed that the combined effects of warming and water stress will likely result in major disturbances of ectomycorrhizal networks and may harm forest resilience and function.
Published Split gene-editing tool offers greater precision
(via sciencedaily.com) To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.
Published Compound derived from hops reduces abundance of gut microbe associated with metabolic syndrome
(via sciencedaily.com) Original source Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.