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Categories: Anthropology: General, Biology: Microbiology
Published Bacteria in cancer unmasked
(via sciencedaily.com) Original source Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.
Published Early medieval money mystery solved
(via sciencedaily.com) Original source Byzantine bullion fueled Europe's revolutionary adoption of silver coins in the mid-7th century, only to be overtaken by silver from a mine in Charlemagne's Francia a century later, new tests reveal. The findings could transform our understanding of Europe's economic and political development.
Published New diagnostic tool achieves accuracy of PCR tests with faster and simpler nanopore system
(via sciencedaily.com) Original source A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Scientists discover new phage resistance mechanism in phage-bacterial arms race
(via sciencedaily.com) Original source Scientists describe a new mechanism impacting the phage-bacterial arms race, a nanosized epibiotic parasite, TM7x, which helps its host bacterium (a Schaalia odontolytica strain called XH001) achieve resistance to lytic phages.
Published Scientists grow 'mini kidneys,' revealing new insights into metabolic defects and potential therapy for polycystic kidney disease
(via sciencedaily.com) Original source Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published How mosquito larva guts could help create highly specific insecticides
(via sciencedaily.com) Original source Did you know that the world's deadliest animal is the mosquito? And Aedes aegypti is one of the most dangerous. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research reports new molecules that label proteins in the unique, alkaline environment of the Ae. aegypti digestive system that could help scientists develop insecticides to fight back.
Published Integrated dataset enables genes-to-ecosystems research
(via sciencedaily.com) Original source A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published eDNA methods give a real-time look at coral reef health
(via sciencedaily.com) Original source The study underscores the crucial role of microbes in maintaining coral reef health, akin to the human gut microbiome. Hurricanes and disease outbreaks affect coral reef water microbial communities, leading to changes that may support further reef decline. Microbial analysis enables prompt assessment of disturbances' impacts on coral reefs, facilitating timely interventions to support reef ecosystems. Environmental DNA (eDNA) analysis offers a noninvasive approach to study coral microbial communities and diagnose reef health.
Published Rapid, simultaneous detection of multiple bacteria achieved with handheld sensor
(via sciencedaily.com) Original source A team has developed a method for simultaneous detection of multiple disease-causing bacterial species within one hour using a handheld device.
Published What four decades of canned salmon reveal about marine food webs
(via sciencedaily.com) Original source Researchers have shown that levels of anisakid worms -- a common marine parasite -- rose in two salmon species in the Gulf of Alaska and Bristol Bay over a 42-year period. The team discovered this by studying salmon caught, killed and canned from 1979 to 2021. Since anisakid worms have a complex life cycle involving multiple types of hosts, the researchers interpret their rising numbers as a potential sign of ecosystem recovery, possibly driven by rising numbers of marine mammals thanks to the 1972 Marine Mammal Protection Act.
Published Finds at Schöningen show wood was crucial raw material 300,000 years ago
(via sciencedaily.com) Original source During archaeological excavations in the Schoningen open-cast coal mine in 1994, the discovery of the oldest, remarkably well-preserved hunting weapons known to humanity caused an international sensation. Spears and a double-pointed throwing stick were found lying between animal bones about ten meters below the surface in deposits at a former lakeshore. In the years that followed, extensive excavations have gradually yielded numerous wooden objects from a layer dating from the end of a warm interglacial period 300,000 years ago. The findings suggested a hunting ground on the lakeshore.
Published New research offers insight into the future understanding of MS and its treatments
(via sciencedaily.com) Original source Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk factor for developing multiple sclerosis (MS). Their findings have implications for future basic research in further understanding the biology of EBV in MS, but also has the potential to be applied in clinical trials that target the virus.
Published Heat flows the secret to order in prebiotic molecular kitchen
(via sciencedaily.com) Original source Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.
Published Microbial signature of colorectal cancer-associated mutations identified in new study
(via sciencedaily.com) Original source Researchers have connected KRAS mutations in colorectal cancer to microbial signatures in the gut.
Published New tools reveal how genes work and cells organize
(via sciencedaily.com) Original source Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.
Published Evolution in action? New study finds possibility of nitrogen-fixing organelles
(via sciencedaily.com) Original source A new study finds that UCYN-A, a species of nitrogen-fixing cyanobacteria, may be evolving organelle-like characteristics.
Published Giant phage holds promise as treatment for lung infections
(via sciencedaily.com) Original source Researchers have discovered a new bacterial killer that can target common lung infection caused by Burkholderia bacteria that has exciting potential for biotechnological applications.