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Categories: Anthropology: Cultures, Biology: Microbiology
Published Observation of a virus attaching to another virus



'Satellite' viruses must be in proximity to their 'helper' virus to replicate, but this research reports the first documented case of a satellite virus attaching itself to its helper virus. Out of 50 observed helpers, 40 had a satellite bound. Bioinformatic analysis of the satellite and helper viruses' genomes provides clues as to why the satellite may have evolved to attach to the helper, and suggests this pair may have been co-evolving for about 100 million years.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells



In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New antibodies neutralize resistant bacteria



Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future.
Published Investigators examine shifts in coral microbiome under hypoxia



A new study provides the first characterization of the coral microbiome under hypoxia, insufficient oxygen in the water.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells



Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans



Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere



A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published The ringed seals in Ilulissat Icefjord, Greenland are special



Local hunters in the Icefjord near Ilulissat have long known about a special ringed seal -- the Kangia seal -- which is significantly larger and has a markedly different fur color and pattern than typical Arctic ringed seals. Now scientific studies have shown that the Kangia ringed seal has been isolated from other ringed seals for a long period of time -- more than 100,000 years.
Published Pinpointing HIV immune response



New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected cells while also killing viral infected cells, but only within a narrow time window at the start of a cell's infection.
Published Maternal microbiota can affect fetal development



Significant differences in the gene activity of the fetal intestine, brain and placenta were identified, depending on the microbes in the mother's body and the compounds produced by them. The findings indicate that maternal microbes are important to her offspring's development and health.
Published New Nijmegen method reveals hidden genetic variations



Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Plastic-eating bacteria turn waste into useful starting materials for other products



Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published Antibiotics for common childhood infections no longer effective



Alarmingly high rates of bacterial resistance to commonly prescribed antibiotics used to treat children and babies has been found in the Asia-Pacific.
Published Risk of viral airborne transmission peaks within 5 seconds of face-to-face encounters



Researchers visualized and measured the flow field of aerosol particles derived from exhaled air and examined the risk of viral exposure during face-to-face encounters, such as while walking, jogging, running, or sprinting. The results showed that the number of aerosol particles during face-to-face encounters peaked within 5 seconds after the encounter and rapidly declined thereafter.
Published How cruise ships can steer clear of viral spread



Researchers examine how ventilation can affect transmission of airborne viruses in a typical cruise ship cabin based on guidelines developed before and after the pandemic. They conducted simulations for virus droplets from a cough in a typical cabin that accommodates two or more people, with different ventilation rates and different positions of the person emitting the cough. Computational fluid dynamics testing ranged from 1.5 to 15 air changes per hour to capture all possible scenarios, from minimal ventilation to rates exceeding the most recent recommendations.
Published Specific gut bacteria increase risk of severe malaria



Researchers have identified multiple species of bacteria that, when present in the gut, are linked to an increased risk of developing severe malaria in humans and mice.
Published How to protect biocatalysts from oxygen



There are high hopes for hydrogen as the key to the energy transition. A specific enzyme group found in algae and in bacteria can produce molecular hydrogen simply by catalyzing protons and electrons. However, the enzyme group is so sensitive to oxygen that commercial use of the hydrogen produced by this process as a green energy source is not yet possible. Researchers have now increased the oxygen stability of a hydrogen-producing enzyme by genetically generated channel blockages.
Published Cat-ching criminals with DNA from pet hairs



Cat hair could be the purr-fect way to catch criminals, according to researchers.
Published Intestinal bacteria metabolite promotes capture of antigens by dendritic cells



Dendritic cells are immune cells that capture and present antigens to T cells, activating an immune response. Researchers have discovered that short-chain fatty acids produced by intestinal bacteria regulate a crucial step in this process, the extension of dendritic 'arms.' This breakthrough finding could potentially lead to the development of disease prevention strategies involving beneficial bacteria and new drugs targeting the regulation of dendritic cell function.
Published Controlling organoids with light



Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.