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Categories: Anthropology: Cultures, Biology: Microbiology

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A simple-to-apply, needle-free vaccine patch is being developed to protect people from the potentially deadly mosquito-borne Zika virus.

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Research suggests that Paleolithic humans in the Middle East selected flint for their cutting tools based on differences in the mechanical properties of the rock. They seem to have purposefully selected the most suitable rocks for fashioning into tools, even being able to distinguish rocks that were unsuitable.

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Pentoses are essential carbohydrates in the metabolism of modern lifeforms, but their availability on early Earth is unclear since these molecules are unstable. Now, researchers reveal a chemical pathway compatible with early Earth conditions, by which C6 aldonates could have acted as a source of pentoses without the need for enzymes. Their findings provide clues about primitive biochemistry and bring us closer to understanding life's origin.

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For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

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Farmland often harbors a multitude of pathogens which attack plants and reduce yields. A research team has now shown that inoculating the soil with mycorrhizal fungi can help maintain or even improve yields without the use of additional fertilizers or pesticides. In a large-scale field trial, plant yield increased by up to 40 percent.

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A new study tackles the mystery of why bacteria often carry diverse ranges of weapons. The findings show that different weapons are best suited to different competition scenarios. Short-range weapons help bacteria to invade established communities; long-range weapons are useful once established.

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Researchers have discovered that growing bacteria on agar mixed with organs is an efficient and effective way to study infectious pathogens.

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A new bacterial species discovered at the deep-sea hydrothermal vent site 'Crab Spa' provides a deeper understanding of bacterial evolution.

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The Second Plague Pandemic of the mid-14th century, also known as the Black Death, killed 30-60 percent of the European population and profoundly changed the course of European history. New research suggests that this plague, potentially through resulting changes in diet and hygiene, may also be associated with a shift in the composition of the human oral microbiome toward one that contributes to chronic diseases in modern-day humans.  

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Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.

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Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).

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Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.

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The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.

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One in 200 newborns is admitted to a neonatal unit with sepsis caused by a bacteria commonly carried by their mothers -- much greater than the previous estimate, say researchers. The team has developed an ultra-sensitive test capable of better detecting the bacteria, as it is missed in the vast majority of cases.

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Researchers have revealed how amphibians and mammals heal musculoskeletal tissues. Using mechanical testing and microscopy, they found that newts heal their tendons using collagenous tissue that acts as a bridge between damaged areas and possesses structure and functions similar to their native tendon. Their findings suggest that newts will serve as a useful model to study tendon regeneration. 

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Extracellular vesicles were found to inhibit the viral infection of COVID-19 and potentially other infectious diseases.

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Scientists have unraveled the evolutionary journey of a unique type of photosynthesis that allows some bacteria to harness far-red light, a region beyond the visible spectrum. This discovery could pave the way for engineering plants with enhanced light absorption capabilities and has implications for our search for extraterrestrial life.

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Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.

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Researchers characterize nearly 600 microbial genomes collected from goldmine. The study illuminates 'microbial dark matter' residing below the surface. Microbes divide into two groups: minimalists that have one, specialized job or maximalists that are prepared to use any available resource. Study has implications for how underground activities, like mining and carbon storage, could affect or be affected by microbial life. The lifestyle of these 'intraterrestrial' microbes also provides hints to what organisms could be living on other planets.

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Researchers have developed a new surgical implant that has the potential to transform the treatment of complex bone infections. When implanted on an injured or infected bone, the material can not only speed up bone healing, it also reduces the risk of infections without the need for traditional antibiotics.