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Categories: Anthropology: Early Humans, Biology: Microbiology
Published Protein network dynamics during cell division
(via sciencedaily.com) Original source An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published The enemy within: How pathogens spread unrecognized in the body
(via sciencedaily.com) Original source Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
Published New research defines specific genomic changes associated with the transmissibility of the monkeypox virus
(via sciencedaily.com) Original source Scientists have located and identified alterations in the monkeypox virus genome that potentially correlate with changes in the virus's transmissibility observed in the 2022 outbreak.
Published Key protein regulates immune response to viruses in mammal cells
(via sciencedaily.com) Original source Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Light show in living cells
(via sciencedaily.com) Original source Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?
(via sciencedaily.com) Original source A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
Published Potential new treatment path for lasting Lyme disease symptoms
(via sciencedaily.com) Original source Researchers have identified a potential new treatment for persistent neurological symptoms of Lyme disease, commonly seen even after antibiotic use. The study found that fibroblast growth factor receptor inhibitors, previously studied in cancer, significantly reduced inflammation and cell death in infected brain and nerve tissues.
Published Metabolic health before vaccination determines effectiveness of anti-flu response
(via sciencedaily.com) Original source The annual influenza vaccine has become less effective on average over time. One reason may be reduced vaccine efficacy in people with obesity than those with a healthier body mass index (BMI), while the number of people with high BMI grows. Findings showed switching mice to a healthy diet four weeks before influenza vaccination protected 100% from a later flu exposure, despite still having a high BMI.
Published Marine microbial populations: Potential sensors of the global change in the ocean
(via sciencedaily.com) Original source Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.
Published RNA's hidden potential: New study unveils its role in early life and future bioengineering
(via sciencedaily.com) Original source The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.
Published Honey bees experience multiple health stressors out-in-the-field
(via sciencedaily.com) Original source It's not a single pesticide or virus stressing honey bees, and affecting their health, but exposure to a complex web of multiple interacting stressors encountered while at work pollinating crops, found new research. Scientists have been unable to explain increasing colony mortality, even after decades of research examining the role of specific pesticides, parasitic mites, viruses or genetics. This led the research team to wonder if previous studies were missing something by focusing on one stressor at a time.
Published Probiotic feed additive boosts growth, health in poultry in place of antibiotics
(via sciencedaily.com) Original source The growing need for antibiotic-free products has challenged producers to decrease or completely stop using antimicrobials as feed supplements in the diet of broiler chickens to improve feed efficiency, growth rate and intestinal health. A research team conducted a study of natural feed additives that are promising alternatives to substitute for antimicrobial growth promoters.
Published New class of antimicrobials discovered in soil bacteria
(via sciencedaily.com) Original source Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors in their crowded microbial communities, especially others of their own species. What makes these newly detected antibacterial toxins different is that, unlike the Streptomyces' small-molecule antibiotics, umbrella toxins are large complexes composed of multiple proteins. They are also far more specific in the bacteria they target. They tend to go after bacteria that form branching filaments, an usual growth pattern among bacteria. The scientists are intrigued by the potential clinical clinical applications of this discovery, because they suspect the pathogens that cause tuberculosis and diphtheria might be sensitive to umbrella toxins.
Published Solving a mini mystery of cell division
(via sciencedaily.com) Original source Trying to hit a target size before dividing seems like the best strategy for maintaining a precise cell size, but bacteria don't do that. Now we know why.
Published Plant sensors could act as an early warning system for farmers
(via sciencedaily.com) Original source Using a pair of sensors made from carbon nanotubes, researchers discovered signals that help plants respond to stresses such as heat, light, or attack from insects or bacteria. Farmers could use these sensors to monitor threats to their crops, allowing them to intervene before the crops are lost.
Published Genetic variant identified that shaped the human skull base
(via sciencedaily.com) Original source Researchers have identified a variant in the gene TBX1 as key in the development of the unique morphology at the base of the skull. TBX1 is present at higher levels in humans than in closely related hominins. Low TBX1 also occurs in certain genetic conditions causing altered skull base morphology. This study provides a greater understanding of human disease and evolution.
Published A better view with new mid-infrared nanoscopy
(via sciencedaily.com) Original source A team has constructed an improved mid-infrared microscope, enabling them to see the structures inside living bacteria at the nanometer scale. Mid-infrared microscopy is typically limited by its low resolution, especially when compared to other microscopy techniques. This latest development produced images at 120 nanometers, which the researchers say is a thirtyfold improvement on the resolution of typical mid-infrared microscopes. Being able to view samples more clearly at this smaller scale can aid multiple fields of research, including into infectious diseases, and opens the way for developing even more accurate mid-infrared-based imaging in the future.
Published Interspecies competition led to even more forms of ancient human -- defying evolutionary trends in vertebrates
(via sciencedaily.com) Original source Competition between species played a major role in the rise and fall of hominins -- and produced a 'bizarre' evolutionary pattern for the Homo lineage -- according to a new study that revises the start and end dates for many of our early ancestors.
Published How soil microbes survive in harsh desert environments
(via sciencedaily.com) Original source Prolonged droughts followed by sudden bursts of rainfall -- how do desert soil bacteria manage to survive such harsh conditions? This long-debated question has now been answered by microbiologists. The study reveals that desert soil bacteria are highly adapted to survive the rapid environmental changes experienced with each rainfall event.
Published E-tongue can detect white wine spoilage before humans can
(via sciencedaily.com) Original source While the electronic tongue bears little physical resemblance to its namesake, the strand-like sensory probes of the 'e-tongue' still outperformed human senses when detecting contaminated wine in a recent study. In a recent experiment, the e-tongue identified signs of microorganisms in white wine within a week after contamination -- four weeks before a human panel noticed the change in aroma. This was also before those microbes could be grown from the wine in a petri-dish. Winemakers traditionally rely on these two methods, sniffing the wine and petri-dish testing, to identify potential wine 'faults' or spoilage.