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Categories: Anthropology: Early Humans, Biology: Microbiology

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Published

Translating nuclear waste site data into microbial ecosystem insights      (via sciencedaily.com)     Original source 

A flagship seven-year study that explores how environmental stresses influence different ecological processes shaping the composition and structure of microbial communities in groundwater has now been published.

Biology: General Biology: Microbiology
Published

New potato-threatening pathogens reported for first time in Pennsylvania, US      (via sciencedaily.com)     Original source 

As the home of many beloved snack companies, Pennsylvania values its potatoes. Tasty tubers across the state may face the threat of newly identified pathogen strains, though, according to researchers who made the finding and aim to develop management strategies.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Offbeat: General Offbeat: Plants and Animals
Published

Ancient 'chewing gum' reveals stone age diet      (via sciencedaily.com)     Original source 

What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.

Biology: Microbiology
Published

HIV antibodies protect animals in proof-of-concept study      (via sciencedaily.com)     Original source 

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. The antibodies -- a human broadly neutralizing antibody and two antibodies isolated from previously vaccinated monkeys -- target the fusion peptide, a site on an HIV surface protein that helps the virus fuse with and enter cells.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Nearly dead plants brought back to life: Keys to aging hidden in the leaves      (via sciencedaily.com)     Original source 

Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Study throws our understanding of gene regulation for a loop      (via sciencedaily.com)     Original source 

To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Machine learning reveals sources of heterogeneity among cells in our bodies      (via sciencedaily.com)     Original source 

A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry Physics: Optics
Published

Glowing COVID-19 diagnostic test prototype produces results in one minute      (via sciencedaily.com)     Original source 

Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.

Biology: Cell Biology Biology: General Biology: Microbiology Offbeat: General Offbeat: Plants and Animals
Published

Tests can reveal whether an antibody can turn into a killer      (via sciencedaily.com)     Original source 

A promising antibody failed testing. This is good news for developing a broad-spectrum antidote against the world's most dangerous snake venoms.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Chemistry: Biochemistry
Published

Unraveling the role of supersulfides in regulating mitochondrial function and longevity      (via sciencedaily.com)     Original source 

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

Biology: Microbiology
Published

One-step synthesis of the most common, yet highly intricate, antibiotic molecular scaffold      (via sciencedaily.com)     Original source 

Researchers have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes the toxicity that is a common feature of similar Fischer-carbene synthetic methodologies, and was used to synthesize the scaffold of the thienamycin antibiotic in high yield. This work is an important advancement in sustainable chemistry that should benefit drug development and other chemical syntheses.

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Microbiology
Published

Candida evolution disclosed: New insights into fungal infections      (via sciencedaily.com)     Original source 

Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bioinformatics: Researchers develop a new machine learning approach      (via sciencedaily.com)     Original source 

To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.

Biology: Microbiology
Published

Many more infected by TBE virus than previously known      (via sciencedaily.com)     Original source 

The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed. This has been shown in a new study of Swedish blood donors.

Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New insights into what helps Salmonella cause infections      (via sciencedaily.com)     Original source 

In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging      (via sciencedaily.com)     Original source 

Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species
Published

New rice lines for Africa offer virus protection      (via sciencedaily.com)     Original source 

The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.

Biology: Biochemistry Biology: Microbiology
Published

Antibiotic use is not the only driver of superbugs, research shows      (via sciencedaily.com)     Original source 

Researchers have analyzed the rise of antibiotic resistance over the last 20 years in the UK and Norway, highlighting that antibiotic use is not the only factor in the increase.