Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology
Published

New worm study paves way for better RNA-based drugs to treat human disease      (via sciencedaily.com)     Original source 

Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.

Anthropology: Early Humans Anthropology: General Geoscience: Geology Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Fossil hotspots in Africa obscure a more complete picture of human evolution      (via sciencedaily.com)     Original source 

A new study shows how the mismatch between where fossils are preserved and where humans likely lived may influence our understanding of early human evolution.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology
Published

Scientists discover new code governing gene activity      (via sciencedaily.com)     Original source 

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Microbiology Computer Science: General Mathematics: Modeling
Published

Peering into the mind of artificial intelligence to make better antibiotics      (via sciencedaily.com)     Original source 

Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Chemistry: Biochemistry Chemistry: General Geoscience: Geochemistry
Published

Key biofuel-producing microalga believed to be a single species is actually three      (via sciencedaily.com)     Original source 

When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

New insights on how bird flu crosses the species barrier      (via sciencedaily.com)     Original source 

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Offbeat: General Offbeat: Plants and Animals
Published

Searching old stem cells that stay young forever      (via sciencedaily.com)     Original source 

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

Low cortisol, hair-trigger stress response in the brain may underlie Long COVID      (via sciencedaily.com)     Original source 

A new animal study shows that exposure to immune-stimulating proteins left behind by COVID-19 leads to lower cortisol, brain inflammation and a heightened reaction to subsequent stressors.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

Mining the microbiome: Uncovering new antibiotics inside the human gut      (via sciencedaily.com)     Original source 

Researchers surveyed the gut microbiomes of nearly 2,000 people, discovering dozens of potential new antibiotics. The lead candidate, prevotellin-2, demonstrated anti-infective capabilities on par with polymyxin B, an FDA-approved antibiotic used today to treat multidrug-resistant infections, suggesting that the human gut microbiome may contain antibiotics that will someday find clinical application.

Biology: Biochemistry Biology: Zoology Ecology: Extinction Ecology: Nature Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Early Mammals and Birds
Published

Rethinking the dodo      (via sciencedaily.com)     Original source 

Researchers are setting out to challenge our misconceptions about the Dodo, one of the most well-known but poorly understood species of bird. Researchers have undertaken the most comprehensive review of the taxonomy of the Dodo and its closest relative, the Rodriguez Island Solitaire.

Biology: Biochemistry Biology: General Biology: Microbiology Ecology: Extinction
Published

The banana apocalypse is near, but biologists might have found a key to their survival      (via sciencedaily.com)     Original source 

The bananas in your supermarket and that you eat for breakfast are facing functional extinction due to the disease Fusarium wilt of banana (FWB) caused by a fungal pathogen called Fusarium oxysporum f.sp. cubense (Foc) tropical race 4 (TR4). However, thanks to recent research from an international team of scientists we now know that Foc TR4 did not evolve from the strain that wiped out commercial banana crops in the 1950s and that the virulence of this new strain seems to be caused by some accessory genes that are associated the production of nitric oxide. The research opens the door to treatments and strategies that can slow, if not control, the as-of-yet unchecked spread of Foc TR4.

Biology: Biochemistry Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Probiotics during pregnancy shown to help moms and babies      (via sciencedaily.com)     Original source 

Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.

Biology: Microbiology
Published

Scientists discover superbug's rapid path to antibiotic resistance      (via sciencedaily.com)     Original source 

Scientists have discovered how the hospital superbug C.diff rapidly evolves resistance to the frontline drug used for treatment in the UK.

Biology: Microbiology
Published

Researchers help to control cancer-causing poison in corn      (via sciencedaily.com)     Original source 

Researchers have demonstrated a promising sterilization technique that uses X-ray irradiation to reduce Aspergillus flavus viability in contaminated corn. This method achieves sterilization without degrading the harmful aflatoxin B1 (AFB1) produced by the fungus.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Surprise finding in study of environmental bacteria could advance search for better antibiotics      (via sciencedaily.com)     Original source 

Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology
Published

Scientists map DNA of Lyme disease bacteria      (via sciencedaily.com)     Original source 

Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.

Biology: Microbiology
Published

Candidate malaria vaccine provides lasting protection in NIH-sponsored trials      (via sciencedaily.com)     Original source 

Recent trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe. One of the trials enrolled 300 healthy women ages 18 to 38 years who anticipated becoming pregnant soon after immunization. That trial began with drug treatment to remove malaria parasites, followed by three injections spaced over a month of either saline placebo or the investigational vaccine at one of two dosages.

Biology: Biochemistry Biology: Cell Biology Biology: Microbiology
Published

Diet is main risk factor for colon cancer in younger adults, new study suggests      (via sciencedaily.com)     Original source 

A new study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (less than 60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.