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Categories: Biology: Microbiology, Paleontology: Fossils

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Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.

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Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.

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A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.

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In a new study, paleontologists describe the oldest-known leaf-nosed bat fossils, which were found along the banks of the Panama Canal. They're also the oldest bat fossils from Central America, preserved 20-million years ago when Panama and the rest of North America were separated from southern landmass by a seaway at least 120 miles wide.

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Researchers analyzed archival samples of bacteria and archaea populations taken from the Beaufort Sea, bordering northwest Canada and Alaska. The samples were collected between 2004 and 2012, a period that included two years -- 2007 and 2012 -- in which the sea ice coverage was historically low. The researchers looked at samples taken from three levels of water: the summer mixed layer, the upper Arctic water below it and the Pacific-origin water at the deepest level. The study examined the microbes' genetic composition using bioinformatics and statistical analysis across the nine-year time span. Using this data, the researchers were able to see how changing environmental conditions were influencing the organisms' structure and function.

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By analysing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

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Researchers are studying how bats can carry deadly viruses, but not develop symptoms. They found that what happens during swarming behavior -- like social gatherings for bats -- may hold the key to understanding their viral tolerance and translate to human health in fighting off diseases like Ebola and COVID-19.

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In a group of plants that is famous for luring its pollinators into a death trap, one species offers its flowers as a nursery in exchange. The discovery blurs the line between mutualism and parasitism and sheds light on the evolution of complex plant-insect interactions.

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Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.

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Armed with a catalog of hundreds of thousands of DNA and RNA virus species in the world's oceans, scientists are now zeroing in on the viruses most likely to combat climate change by helping trap carbon dioxide in seawater or, using similar techniques, different viruses that may prevent methane's escape from thawing Arctic soil.

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Until recently, Orthacanthus gracilis could have been considered the 'John Smith' of prehistoric shark names, given how common it was. Three different species of sharks from the late Paleozoic Era -- about 310 million years ago -- were mistakenly given that same name, causing lots of grief to paleontologists who studied and wrote about the sharks through the years and had trouble keeping them apart. But now a professor has finished the arduous task of renaming two of the three sharks -- and in the process rediscovered a wealth of fossil fishes that had been stored at a museum for years but had been largely forgotten.

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Palaeontological analysis shows that a renowned fossil thought to show soft tissue preservation is in fact just paint. The fossil discovered in 1931 was thought to be an important specimen for understanding early reptile evolution. While not all of the celebrated fossil is a forgery, scientists urge caution in how the fossil is utilized in future.

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Researchers studied the composition and function of bacteria in the seabed off Svalbard, during alternating periods of polar night and midnight sun. To do this, they specially developed a sampling device, the Ellrott grab. In contrast with bacterial communities in the overlying water, the sediment bacteria hardly change with the seasons. This is probably due to the fact that in the seabed some hard-to-digest foods are available all year round.

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Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

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New research has shown that the tropical subsurface ocean gained oxygen during the Paleocene-Eocene Thermal Maximum (commonly referred to as PETM). During this short-lived interval of time in Earth s history that occurred 56 million years ago the average temperatures rose by up to six degrees within a few thousand years.

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A new antibiotic overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

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Researchers can accurately track where typhoid fever cases are highest by monitoring environmental samples for viruses called bacteriophages that specifically infect the bacterium that causes typhoid fever.

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A new model bridges the rules of life at the individual scale and the ecosystem level, which could open new avenues of exploration in ecology, global change biology, and ultimately ecosystem management.

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Scientists may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.

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Researchers found that the oral bacterium Streptococcus gordonii activates another bacterial species, Fusobacterium nucleatum, to produce large quantities of methyl mercaptan, a compound responsible for bad breath. Disrupting this interaction could therefore help treat halitosis, and possibly also help prevent the development of more serious tooth and gum disease.