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Categories: Biology: Microbiology, Offbeat: Space
Published Tackling antibiotic resistance when treating pneumonia
(via sciencedaily.com) Original source New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).
Published Translating nuclear waste site data into microbial ecosystem insights
(via sciencedaily.com) Original source A flagship seven-year study that explores how environmental stresses influence different ecological processes shaping the composition and structure of microbial communities in groundwater has now been published.
Published New potato-threatening pathogens reported for first time in Pennsylvania, US
(via sciencedaily.com) Original source As the home of many beloved snack companies, Pennsylvania values its potatoes. Tasty tubers across the state may face the threat of newly identified pathogen strains, though, according to researchers who made the finding and aim to develop management strategies.
Published Ancient 'chewing gum' reveals stone age diet
(via sciencedaily.com) Original source What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.
Published HIV antibodies protect animals in proof-of-concept study
(via sciencedaily.com) Original source Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. The antibodies -- a human broadly neutralizing antibody and two antibodies isolated from previously vaccinated monkeys -- target the fusion peptide, a site on an HIV surface protein that helps the virus fuse with and enter cells.
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves
(via sciencedaily.com) Original source Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published Astronomers detect oldest black hole ever observed
(via sciencedaily.com) Original source Researchers have discovered the oldest black hole ever observed, dating from the dawn of the universe, and found that it is 'eating' its host galaxy to death.
Published The metalens meets the stars
(via sciencedaily.com) Original source Researchers have developed a 10-centimeter-diameter glass metalens that can image the sun, the moon and distant nebulae with high resolution. It is the first all-glass, large-scale metalens in the visible wavelength that can be mass produced using conventional CMOS fabrication technology.
Published Study throws our understanding of gene regulation for a loop
(via sciencedaily.com) Original source To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute
(via sciencedaily.com) Original source Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published Space solar power project ends first in-space mission with successes and lessons
(via sciencedaily.com) Original source A 10-month mission demonstrated three elements of the plan to beam solar power from space to Earth.
Published New technology for conducting deep-sea research on fragile organisms
(via sciencedaily.com) Original source Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.
Published Tests can reveal whether an antibody can turn into a killer
(via sciencedaily.com) Original source A promising antibody failed testing. This is good news for developing a broad-spectrum antidote against the world's most dangerous snake venoms.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity
(via sciencedaily.com) Original source Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Discovery changes understanding of water's history on the Moon
(via sciencedaily.com) Original source New research shows the early lunar crust which makes up the surface of the Moon was considerably enriched in water more than 4 billion years ago, counter to previously held understanding.
Published One-step synthesis of the most common, yet highly intricate, antibiotic molecular scaffold
(via sciencedaily.com) Original source Researchers have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes the toxicity that is a common feature of similar Fischer-carbene synthetic methodologies, and was used to synthesize the scaffold of the thienamycin antibiotic in high yield. This work is an important advancement in sustainable chemistry that should benefit drug development and other chemical syntheses.
Published Research sheds new light on Moon rock formation solving major puzzle in lunar geology
(via sciencedaily.com) Original source New research has cracked a vital process in the creation of a unique rock type from the Moon. The discovery explains its signature composition and very presence on the lunar surface at all, unraveling a mystery which has long-eluded scientists.
Published Candida evolution disclosed: New insights into fungal infections
(via sciencedaily.com) Original source Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.