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Categories: Biology: Microbiology, Offbeat: Paleontology and Archeology
Published What shapes a virus's pandemic potential? SARS-CoV-2 relatives yield clues
(via sciencedaily.com) Original source Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the COVID-19-causing virus, a new study reveals. The findings provide clues as to why some viruses have greater 'pandemic potential' than others and how researchers might go about identifying those that do before they become widespread.
Published Platypus and chicken reveal how chromosomes balance between the sexes
(via sciencedaily.com) Original source Geneticists uncover new insights into how sex chromosome systems work in the platypus and the chicken -- which will lead to better understandings of our own sex chromosome evolution and gene regulation.
Published How researchers turn bacteria into cellulose-producing mini-factories
(via sciencedaily.com) Original source Researchers have modified certain bacteria with UV light so that they produce more cellulose. The basis for this is a new approach with which the researchers generate thousands of bacterial variants and select those that have developed into the most productive.
Published MicroRNA study sets stage for crop improvements
(via sciencedaily.com) Original source MicroRNAs can make plants more capable of withstanding drought, salinity, pathogens and more. However, in a recent study scientists showed just how much we didn't know about the intricate processes plants use to produce them.
Published Winter breeding offers lifeline for monarch butterflies in Northern California
(via sciencedaily.com) Original source Monarch butterflies in Northern California are adapting to a changing climate by embracing an unexpected strategy: breeding in the winter. The shift could be key to the survival of the iconic insect, according to a new study.
Published Fetal brain impacted when mom fights severe flu: New mouse study explains how
(via sciencedaily.com) Original source New research using live mouse-adapted influenza virus improves upon previous mouse experiments to explain how maternal infection impacts fetal brain development. The study also indicates fetal brain changes are more likely once the severity of the mother's infection meets a specific threshold.
Published New progress in research into malignant catarrhal fever in cattle
(via sciencedaily.com) Original source A research team has published a groundbreaking study on malignant catarrhal fever (MCF). This disease is caused by the alcelaphine gammaherpesvirus 1 (AlHV-1), which infects its natural host, the wildebeest. This study sheds light on the mechanisms by which this virus, which is asymptomatic and latent in the wildebeest, causes an oligoclonal expansion of CD8+ T lymphocytes in cattle, leading to the development of MCF.
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration
(via sciencedaily.com) Original source A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published Virus that causes COVID-19 is widespread in wildlife, scientists find
(via sciencedaily.com) Original source SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.
Published The ancestor of all modern birds probably had iridescent feathers
(via sciencedaily.com) Original source Birds tend to be more colorful in the tropics, and scientists wanted to find out how they got there: if colorful feathers evolved in the tropics, or if tropical birds have brightly-colored ancestors that came to the region from somwhere else. Scientists built a database of 9,409 birds to explore the spread of color across the globe. They found that iridescent, colorful feathers originated 415 times across the bird tree of life, and in most cases, arose outside of the tropics -- and that the ancestor of all modern birds likely had iridescent feathers, too.
Published Lampreys possess a 'jaw-dropping' evolutionary origin
(via sciencedaily.com) Original source Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.
Published New drug shows promise in clearing HIV from brain
(via sciencedaily.com) Original source An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.
Published Chemical analyses find hidden elements from renaissance astronomer Tycho Brahe's alchemy laboratory
(via sciencedaily.com) Original source Danish Tycho Brahe was most famous for his contributions to astronomy. However, he also had a well-equipped alchemical laboratory where he produced secret medicines for Europe's elite.
Published Ancient marine animal had inventive past despite being represented by few species
(via sciencedaily.com) Original source Brachiopods were evolving in new directions but this did not turn into evolutionary success in terms of the numbers of species, researchers have found.
Published Rock art and archaeological record reveal humans' complex relationship with Amazonian animals
(via sciencedaily.com) Original source Rock art explored by archaeologists in the Colombian Amazon has provided an insight into the complex relationship between the earliest settlers on the continent and the animals they encountered.
Published Scientists identify key protein behind spread of shingles virus
(via sciencedaily.com) Original source Scientists have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from the original site of infection.
Published In clinical trial, fecal matter transplant helped half of patients with gastrointestinal cancers overcome resistance to immunotherapy treatment
(via sciencedaily.com) Original source Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers. In the study, six of 13 patients who had previously shown resistance to immune checkpoint inhibitors benefited from receiving FMTs from donors who had previously responded to treatment. The investigators also identified specific strains of bacteria associated with better or worse responses to FMT and immune checkpoint drugs.
Published How a bacterium supports healing of chronic diabetic wounds
(via sciencedaily.com) Original source New research shows that a certain bug, Alcaligenes faecalis (A. faecalis), can facilitate healing of hard-to-treat wounds among people with diabetes. While there are many studies done on potentially harmful bacteria in wounds, the researchers discovered that A. faecalis, a bacterium found in many types of chronic wounds, actually boosts healing of diabetic wounds. The researchers found that the beneficial bacterium can promote skin cell movements that are essential for wound closure by inhibiting enzymes that are over-produced in people with diabetes.
Published How evolution tamed a deadly virus and why we should still worry
(via sciencedaily.com) Original source Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death. The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other viral diseases.
Published Seven steps to achieving the right to clean indoor air post-pandemic
(via sciencedaily.com) Original source Seven lessons learned from the COVID-19 pandemic about ventilation's crucial role in preventing the spread of airborne pathogens has been set out in a new article.