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Categories: Biology: Microbiology, Offbeat: Paleontology and Archeology
Published Candidate malaria vaccine provides lasting protection in NIH-sponsored trials
(via sciencedaily.com) Original source Recent trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe. One of the trials enrolled 300 healthy women ages 18 to 38 years who anticipated becoming pregnant soon after immunization. That trial began with drug treatment to remove malaria parasites, followed by three injections spaced over a month of either saline placebo or the investigational vaccine at one of two dosages.
Published Diet is main risk factor for colon cancer in younger adults, new study suggests
(via sciencedaily.com) Original source A new study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (less than 60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.
Published A taste for carbon dioxide
(via sciencedaily.com) Original source The remarkable affinity of the microbial enzyme iron nitrogenase for the greenhouse gas CO2 makes it promising for future biotechnologies.
Published Hydrometeorology and location affect hospitalizations for waterborne infectious diseases in the US
(via sciencedaily.com) Original source An analysis of 12 years of data collected from over 500 hospitals in 25 different states shows that weather, geographic location, and urban or rural location all appear to influence hospitalizations for waterborne infectious diseases.
Published Revealing the mysteries within microbial genomes
(via sciencedaily.com) Original source A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published Rare archaeological site reveals 'surprising' Neanderthal behaviour at Pyrenees foothills
(via sciencedaily.com) Original source An unchartered area in the foothills of the Southern Pyrenees in Spain is providing insights into a poorly known period of Neanderthal history, offering clues that could help archaeologists uncover the mystery of their downfall, according to new research.
Published Trojan horse method gives malaria parasites a taste of their own medicine
(via sciencedaily.com) Original source More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive. Now, scientists say its role as a basic building block of life holds the key to treating deadly diseases caused by parasites, including malaria.
Published Hand washing is important -- but is your sink clean?
(via sciencedaily.com) Original source Handbasins are hotspots for dangerous microbes that can cause illnesses including pneumonia, Legionnaires' disease and wound infections, a new study warns. The environmental health study found handbasin biofilms contained a diverse range of pathogens including microbes typically found in water, and other pathogens not found in water.
Published Could manure and compost act like probiotics, reducing antibiotic resistance in urban soils?
(via sciencedaily.com) Original source Research suggests that, in some cases, boosting urban soil health with compost and treated manure may reduce the amount of pathogenic and anti-biotic resistant bacteria.
Published Great Scott! Stonehenge's Altar Stone origins reveal advanced ancient Britain
(via sciencedaily.com) Original source New research has revealed Stonehenge's monumental six-ton Altar Stone, long believed to originate from Wales, actually hails from Scotland.
Published C-section antibiotics impact the infant microbiome far less than infant diet
(via sciencedaily.com) Original source Caesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site. But there have been concerns about whether these antibiotics may have a negative impact on newborns and their microbiomes if the drugs travel through the umbilical cord and reach the baby before the cord is cut. Now, a study has confirmed that although these antibiotics can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Newly discovered ability of comammox bacteria could help reduce nitrous oxide emissions in agriculture
(via sciencedaily.com) Original source An international research team has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions.
Published Giant fossil seeds from Borneo record ancient plant migration
(via sciencedaily.com) Original source Ancient fossil beans about the size of modern limes, and among the largest seeds in the fossil record, may provide new insight into the evolution of today's diverse Southeast Asian and Australian rainforests, according to researchers who identified the plants.
Published New interpretation of runic inscription reveals pricing in Viking age
(via sciencedaily.com) Original source A new interpretation of the runic inscription on the Forsa Ring (Forsaringen in Swedish), provides fresh insights into the Viking Age monetary system and represents the oldest documented value record in Scandinavia. The inscription describes how the Vikings handled fines in a flexible and practical manner.
Published Pit-building venom mixers
(via sciencedaily.com) Original source Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Rewriting the evolutionary history of critical components of the nervous system
(via sciencedaily.com) Original source A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
(via sciencedaily.com) Original source Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.