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Categories: Biology: Microbiology, Chemistry: Biochemistry
Published New progress in research into malignant catarrhal fever in cattle
(via sciencedaily.com) Original source A research team has published a groundbreaking study on malignant catarrhal fever (MCF). This disease is caused by the alcelaphine gammaherpesvirus 1 (AlHV-1), which infects its natural host, the wildebeest. This study sheds light on the mechanisms by which this virus, which is asymptomatic and latent in the wildebeest, causes an oligoclonal expansion of CD8+ T lymphocytes in cattle, leading to the development of MCF.
Published Researchers trap atoms, forcing them to serve as photonic transistors
(via sciencedaily.com) Original source Researchers have developed a means to realize cold-atom integrated nanophotonic circuits.
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration
(via sciencedaily.com) Original source A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published Hair follicle models from the 3D printer
(via sciencedaily.com) Original source Hair follicle infections are often difficult to treat because bacteria settle in the gap between hair and skin, where it is difficult for active substances to reach them. In order to investigate this scenario more closely in the laboratory, researchers have now developed a model with human hair follicles embedded in a matrix produced using 3D printing. In the future, this model can be used to test the effectiveness of new drug candidates against corresponding pathogens directly on human follicles.
Published Plant-inspired polymers for water purification
(via sciencedaily.com) Original source Researchers have synthesized a bio-inspired polymer for water purification. The polymer was designed to mimic phytochelatin, a plant protein that selectively captures and neutralizes harmful heavy metal ions. The hyperconfinement of the polymer enabled a flow-through system and effectively removed cadmium ions from contaminated water, making it safe to drink. The system was selective for heavy metals and provides a new way to remove specific contaminants from water.
Published Virus that causes COVID-19 is widespread in wildlife, scientists find
(via sciencedaily.com) Original source SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.
Published New additive process can make better -- and greener -- high-value chemicals
(via sciencedaily.com) Original source Researchers have achieved a significant breakthrough that could lead to better -- and greener -- agricultural chemicals and everyday products. Using a process that combines natural enzymes and light, the team developed an eco-friendly way to precisely mix fluorine, an important additive, into chemicals called olefins -- hydrocarbons used in a vast array of products, from detergents to fuels to medicines. This groundbreaking method offers an efficient new strategy for creating high-value chemicals with potential applications in agrochemicals, pharmaceuticals, renewable fuels, and more.
Published Win-win potential of grass-powered energy production
(via sciencedaily.com) Original source Researchers modeled the impact of using anaerobic digestion to produce renewable natural gas from grassy biomass in different settings and from varying perspectives, analysis that helps flesh out the system's potential.
Published New understanding of fly behavior has potential application in robotics, public safety
(via sciencedaily.com) Original source Scientists have identified an automatic behavior in flies that helps them assess wind conditions -- its presence and direction -- before deploying a strategy to follow a scent to its source. The fact that they can do this is surprising -- can you tell if there's a gentle breeze if you stick your head out of a moving car? Flies aren't just reacting to an odor with a preprogrammed response: they are responding in context-appropriate manner. This knowledge potentially could be applied to train more sophisticated algorithms for scent-detecting drones to find the source of chemical leaks.
Published Fresh light on the path to net zero
(via sciencedaily.com) Original source Researchers have used magnetic fields to reveal the mystery of how light particles split. Scientists are closer to giving the next generation of solar cells a powerful boost by integrating a process that could make the technology more efficient by breaking particles of light photons into small chunks.
Published New drug shows promise in clearing HIV from brain
(via sciencedaily.com) Original source An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.
Published 'Miracle' filter turns store-bought LEDs into spintronic devices
(via sciencedaily.com) Original source Scientists transformed existing optoelectronic devices into ones that can control electron spin at room temperature, without a ferromagnet or magnetic field. Researchers replaced the electrodes of store-bought LEDs with a patented spin filter made from hybrid organic-inorganic halide perovskite.
Published How molecular interactions make it possible to overcome the energy barrier
(via sciencedaily.com) Original source Non-reciprocal interactions allow the design of more efficient molecular systems. Scientists now propose a mechanism on how energy barriers in complex systems can be overcome. These findings can help to engineer molecular machines and to understand the self-organization of active matter.
Published Quantum sensor for the atomic world
(via sciencedaily.com) Original source In a scientific breakthrough, an international research team has developed a quantum sensor capable of detecting minute magnetic fields at the atomic length scale. This pioneering work realizes a long-held dream of scientists: an MRI-like tool for quantum materials.
Published Nonreciprocal interactions go nonlinear
(via sciencedaily.com) Original source Using two optically trapped glass nanoparticles, researchers observed a novel collective Non-Hermitian and nonlinear dynamic driven by nonreciprocal interactions. This contribution expands traditional optical levitation with tweezer arrays by incorporating the so called non-conservative interactions.
Published Researchers explore the interplay between high-affinity DNA and carbon nanotubes
(via sciencedaily.com) Original source Single-walled carbon nanotubes (SWCNTs) hold promise for biomedicine and nanoelectronics, yet the functionalization with single-stranded DNA (ssDNA) remains a challenge. Researchers using high-affinity ssDNA sequences identified through high-throughput selection. They demonstrated the effectivity and stability of these constructs using molecular dynamics simulations. Machine-learning models were used to accurately predict patterns that govern ssDNA-SWCNT binding affinity. These findings provide valuable insights into the interactions between ssDNA and SWCNTs.
Published Scientists identify key protein behind spread of shingles virus
(via sciencedaily.com) Original source Scientists have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from the original site of infection.
Published In clinical trial, fecal matter transplant helped half of patients with gastrointestinal cancers overcome resistance to immunotherapy treatment
(via sciencedaily.com) Original source Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers. In the study, six of 13 patients who had previously shown resistance to immune checkpoint inhibitors benefited from receiving FMTs from donors who had previously responded to treatment. The investigators also identified specific strains of bacteria associated with better or worse responses to FMT and immune checkpoint drugs.
Published A recipe for zero-emissions fuel: Soda cans, seawater, and caffeine
(via sciencedaily.com) Original source Engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen -- which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.
Published How a bacterium supports healing of chronic diabetic wounds
(via sciencedaily.com) Original source New research shows that a certain bug, Alcaligenes faecalis (A. faecalis), can facilitate healing of hard-to-treat wounds among people with diabetes. While there are many studies done on potentially harmful bacteria in wounds, the researchers discovered that A. faecalis, a bacterium found in many types of chronic wounds, actually boosts healing of diabetic wounds. The researchers found that the beneficial bacterium can promote skin cell movements that are essential for wound closure by inhibiting enzymes that are over-produced in people with diabetes.