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Categories: Biology: Microbiology, Chemistry: Biochemistry

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Engineering researchers have successfully developed a quantum microprocessor chip for molecular spectroscopy simulation of actual large-structured and complex molecules.

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Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.

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When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.

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Detecting diseases early requires the rapid, continuous and convenient monitoring of vital biomarkers. Researchers have now developed a novel sensor that enables the continuous, and real-time detection of solid-state epidermal biomarkers, a new category of health indicators. The team's wearable, stretchable, hydrogel-based sensor overcomes the limitations of current methods that rely on biofluid samples, such as blood, urine and sweat. This makes it a promising alternative for wearable, continuous, and real-time health monitoring, facilitating the early detection of conditions such as cardiovascular diseases and stroke.

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The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.

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The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.

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A new animal study shows that exposure to immune-stimulating proteins left behind by COVID-19 leads to lower cortisol, brain inflammation and a heightened reaction to subsequent stressors.

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Circadian rhythms appear to influence vulnerability to malaria parasites.

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A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible with an approach that combines an electron microscope, a small sample holder with microscopic channels, and computer simulations, according to a new study.

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Two new studies are pointing the way toward round-the-clock personalized care for people with Parkinson's disease through an implanted device that can treat movement problems during the day and insomnia at night.

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Researchers surveyed the gut microbiomes of nearly 2,000 people, discovering dozens of potential new antibiotics. The lead candidate, prevotellin-2, demonstrated anti-infective capabilities on par with polymyxin B, an FDA-approved antibiotic used today to treat multidrug-resistant infections, suggesting that the human gut microbiome may contain antibiotics that will someday find clinical application.

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Researchers developed a novel reagent that enhances the precision of drug synthesis. This innovative method introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.

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The bananas in your supermarket and that you eat for breakfast are facing functional extinction due to the disease Fusarium wilt of banana (FWB) caused by a fungal pathogen called Fusarium oxysporum f.sp. cubense (Foc) tropical race 4 (TR4). However, thanks to recent research from an international team of scientists we now know that Foc TR4 did not evolve from the strain that wiped out commercial banana crops in the 1950s and that the virulence of this new strain seems to be caused by some accessory genes that are associated the production of nitric oxide. The research opens the door to treatments and strategies that can slow, if not control, the as-of-yet unchecked spread of Foc TR4.

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A study expands understanding on how electrons move through the conductive parts of complex fluids found in electrochemical devices such as batteries. This work can help overcome existing knowledge gaps for engineers seeking to improve the performance of these devices.

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Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.

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Scientists have discovered how the hospital superbug C.diff rapidly evolves resistance to the frontline drug used for treatment in the UK.

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Researchers have demonstrated a technique for printing thin metal oxide films at room temperature, and have used the technique to create transparent, flexible circuits that are both robust and able to function at high temperatures.

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Researchers have demonstrated a promising sterilization technique that uses X-ray irradiation to reduce Aspergillus flavus viability in contaminated corn. This method achieves sterilization without degrading the harmful aflatoxin B1 (AFB1) produced by the fungus.

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Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

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Researchers have developed a new theoretical modelling technique that could potentially be used in the development of switches or amplifiers in molecular electronics.