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Categories: Biology: Microbiology
Published Trojan horse method gives malaria parasites a taste of their own medicine
(via sciencedaily.com) Original source More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive. Now, scientists say its role as a basic building block of life holds the key to treating deadly diseases caused by parasites, including malaria.
Published Hand washing is important -- but is your sink clean?
(via sciencedaily.com) Original source Handbasins are hotspots for dangerous microbes that can cause illnesses including pneumonia, Legionnaires' disease and wound infections, a new study warns. The environmental health study found handbasin biofilms contained a diverse range of pathogens including microbes typically found in water, and other pathogens not found in water.
Published Could manure and compost act like probiotics, reducing antibiotic resistance in urban soils?
(via sciencedaily.com) Original source Research suggests that, in some cases, boosting urban soil health with compost and treated manure may reduce the amount of pathogenic and anti-biotic resistant bacteria.
Published C-section antibiotics impact the infant microbiome far less than infant diet
(via sciencedaily.com) Original source Caesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site. But there have been concerns about whether these antibiotics may have a negative impact on newborns and their microbiomes if the drugs travel through the umbilical cord and reach the baby before the cord is cut. Now, a study has confirmed that although these antibiotics can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Newly discovered ability of comammox bacteria could help reduce nitrous oxide emissions in agriculture
(via sciencedaily.com) Original source An international research team has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions.
Published Pit-building venom mixers
(via sciencedaily.com) Original source Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Rewriting the evolutionary history of critical components of the nervous system
(via sciencedaily.com) Original source A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
(via sciencedaily.com) Original source Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Pre-surgical antibody treatment might prevent heart transplant rejection
(via sciencedaily.com) Original source Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial immunity intact.
Published Bacteria in lakes fight climate change
(via sciencedaily.com) Original source Methane-oxidizing bacteria could play a greater role than previously thought in preventing the release of climate-damaging methane from lakes, researchers from Bremen report. They also show who is behind the process and how it works.
Published Low magnesium levels increase disease risk
(via sciencedaily.com) Original source A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.
Published How mortal filaments' self-assemble and maintain order: Align or die
(via sciencedaily.com) Original source A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.
Published Parents' eating behavior influences how their children respond to food
(via sciencedaily.com) Original source Young children often display similar eating behavior as their parents, with a parent's own eating style influencing how they feed their children.
Published The threat of mpox has returned, but public knowledge about it has declined
(via sciencedaily.com) Original source As the threat of mpox returns, a survey finds that U.S. adults no longer know as much about the disease as they did during the outbreak of 2022.
Published A new mechanism for shaping animal tissues
(via sciencedaily.com) Original source A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.
Published New two-step flu vaccine strategy shows promise in pig model
(via sciencedaily.com) Original source A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs, researchers report.
Published Bacteria encode hidden genes outside their genome--do we?
(via sciencedaily.com) Original source A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.