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Categories: Biology: Biotechnology, Environmental: General
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Forest restoration can boost people, nature and climate simultaneously
(via sciencedaily.com) Original source Forest restoration can benefit humans, boost biodiversity and help tackle climate change simultaneously, new research suggests.
Published Bacteria in lakes fight climate change
(via sciencedaily.com) Original source Methane-oxidizing bacteria could play a greater role than previously thought in preventing the release of climate-damaging methane from lakes, researchers from Bremen report. They also show who is behind the process and how it works.
Published Low magnesium levels increase disease risk
(via sciencedaily.com) Original source A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.
Published Mature forests vital in frontline fight against climate change
(via sciencedaily.com) Original source Mature forests have a key role to play in the fight against climate change -- extracting carbon dioxide (CO2) from the atmosphere and locking it into new wood.
Published Balancing technology and governance are key to achieving climate goals
(via sciencedaily.com) Original source Despite advancements in clean energy, global CO2 emissions continue to rise. IIASA researchers contributed to a new international study that underscores the importance of integrating technological advancements with robust institutional capacities to formulate effective climate policies.
Published Innovative study unveils a new path in green chemistry
(via sciencedaily.com) Original source Researchers have introduced a new advancement in the fight against climate change. Their study showcases a novel method for understanding the mechanisms of carbon dioxide re-utilization leading to fuels and chemicals. This work paves the road for the further optimization of this catalytic process driven by renewable electricity.
Published Drug protects against air pollution-related Alzheimer's signs in mice
(via sciencedaily.com) Original source A new study shows how feeding mice a drug called GSM-15606 provided protection against air pollution-related increases in proteins linked to Alzheimer's disease.
Published Taking a 'one in a million' shot to tackle dopamine-linked brain disorders
(via sciencedaily.com) Original source With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.
Published Just say 'climate change' -- not 'climate emergency'
(via sciencedaily.com) Original source The familiar terms 'climate change' and 'global warming' are more likely to resonate with people than other commonly used phrases.
Published An appetizer can stimulate immune cells' appetite, a boon for cancer treatments
(via sciencedaily.com) Original source The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer. Macrophages have a delicate task. It's crucial that they ignore healthy cells while on patrol, otherwise they could trigger an autoimmune response while performing their duties.
Published New genetically engineered wood can store carbon and reduce emissions
(via sciencedaily.com) Original source Researchers genetically modified poplar trees to produce high-performance, structural wood without the use of chemicals or energy intensive processing.
Published A new mechanism for shaping animal tissues
(via sciencedaily.com) Original source A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.
Published As temperatures break records, many are unaware of symptoms of heat-related illnesses
(via sciencedaily.com) Original source Following record breaking heat, a survey reveals that most Americans do not know where their local cooling centers are in cases of extreme heat.
Published Canadian wildfires are affecting US air quality and raising health concerns
(via sciencedaily.com) Original source Climate-driven wildfire events are rapidly transferring harmful particulate matter containing toxic chemicals over long distances, compromising air quality in the New Jersey and New York City areas, according to recent research.
Published New mechanism to cool buildings while saving energy
(via sciencedaily.com) Original source The movement of radiant heat -- felt when a hot surface warms our bodies and homes -- between buildings and their surroundings at ground level makes buildings with less skyward-facing surfaces harder to cool. A research team has demonstrated a new passive cooling technology that coats walls and windows with materials that can better manage heat movement between buildings and their surroundings at ground level. Findings could reduce the reliance on air conditioning and provide a more environmentally friendly, low-cost and scalable option for low-income communities with limited or no access to cooling and heating systems.
Published New two-step flu vaccine strategy shows promise in pig model
(via sciencedaily.com) Original source A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs, researchers report.
Published Millions of years for plants to recover from global warming
(via sciencedaily.com) Original source Catastrophic volcanic eruptions that warmed the planet millions of years ago shed new light on how plants evolve and regulate climate. Researchers reveal the long-term effects of disturbed natural ecosystems on climate in geological history and its implications for today.
Published Largest protein yet discovered builds algal toxins
(via sciencedaily.com) Original source While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.
Published Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy
(via sciencedaily.com) Original source Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.