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Categories: Biology: Cell Biology, Environmental: General

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Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.

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Being born in autumn or winter is associated with asthma and allergic rhinitis in Finland, a new registry-based study shows.

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In 2017, the Minamata Convention on Mercury went into effect, designed to help curb mercury emissions and limit exposure across the globe. However, a new study of mercury levels in soil suggests that the treaty's provisions might not be enough. The study estimates that soil stores substantially more mercury than previously thought, and it predicts that increases in plant growth due to climate change may add even more.

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Research suggests that, in some cases, boosting urban soil health with compost and treated manure may reduce the amount of pathogenic and anti-biotic resistant bacteria.

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Using nighttime lightdata from NASA, remote sensing, official outage records and census information, a study reveals notable differences in power-restoration rates between urbanized and rural areas and between disadvantaged and more affluent communities after Hurricane Michael in Florida's Panhandle. Block groups with higher proportions of minorities, multi-family housing units, rural locations, and households receiving public assistance experienced slower restoration of power compared to urban and more affluent neighborhoods.

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Caesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site. But there have been concerns about whether these antibiotics may have a negative impact on newborns and their microbiomes if the drugs travel through the umbilical cord and reach the baby before the cord is cut. Now, a study has confirmed that although these antibiotics can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.

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Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.

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Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.

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Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.

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An international research team has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions.

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Unprecedented wildfires in Canada and parts of Amazonia last year were at least three times more likely due to climate change and contributed to high levels of CO2 emissions from burning globally, according to the a new systematic review. The State of Wildfires report takes stock of extreme wildfires of the 2023-2024 fire season (March 2023-February 2024), explains their causes, and assesses whether events could have been predicted. It also evaluates how the risk of similar events will change in future under different climate change scenarios.

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Researchers have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells -- called 'oocytes' -- to become viable embryos, which is a crucial step in assisted reproduction in horses.

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A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.

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Linked to cardiovascular and respiratory diseases in people, nanoplastics continue to build up, largely unnoticed, in the world's bodies of water. The challenge remains to develop a cost-effective solution to get rid of nanoplastics while leaving clean water behind. That's where Mizzou comes in. Recently, researchers created a new liquid-based solution that eliminates more than 98% of these microscopic plastic particles from water.

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A recent study details how trees in New York City and Boston are more negatively impacted by heat waves and drought than trees of the same species in nearby rural forests. The finding highlights the challenges urban trees face in the context of climate change and underscores the importance of tailored urban forestry management as a tool for protecting tree species and reducing urban heat islands.

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Planet-warming greenhouse gas emissions associated with the global food supply chains induced by diets could fall by 17% if people change their food choices towards more plant-based diets.

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Higher intake of heme iron, the type found in red meat and other animal products -- as opposed to non-heme iron, found mostly in plant-based foods -- was associated with a higher risk of developing type 2 diabetes (T2D) in a new study. While the link between heme iron and T2D has been reported previously, the study's findings more clearly establish and explain the link.

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The smaller carbon footprint, or wheel print, of automatic delivery robots can encourage consumers to use them when ordering food, according to a new study. The suitcase-sized, self-driving electric vehicles are much greener than many traditional food delivery methods because they have low, or even zero, carbon emissions. In this study, participants who had more environmental awareness and knowledge about carbon emissions were more likely to choose the robots as a delivery method. The green influence went away though when people perceived the robots as a high-risk choice -- meaning they worried that their food would be late, cold or otherwise spoiled before it arrived.

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Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.

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A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.