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Categories: Biology: Molecular, Environmental: General
Published The future of canine stem cell therapy: unprecedented, painless, and feeder-free



Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.
Published The key mechanism to cell growth has been elucidated



Researchers have discovered how amino acids activate a key cell, TORC1, which is a master regulator in living organisms that controls whether cells grow or recycle their contents in yeast. Notably, the team found that the amino acid cysteine is sensed by a protein called Pib2 and that the two bind together to trigger TORC1. This is important because faulty TORC1 has been linked to disease such as cancer.
Published Novel catalyst system for CO2 conversion



Researchers are constantly pushing the limits of technology by breaking new ground in CO2 conversion. Their goal is to turn the harmful greenhouse gas into a valuable resource. A novel catalyst system could help reach that goal.
Published How national policies affect forests in border regions



How do national policies impact deforestation? Researchers have looked into this question at the global scale and have found that, contrary to common assumptions, national strategies have a significant -- and visible -- influence on efforts to protect forest heritage.
Published Bugs that help bugs: How environmental microbes boost fruit fly reproduction



A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.
Published Researchers solve mystery behind DnaA protein's role in DNA replication initiation



Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation



Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper



A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Discovery: Plants use 'Trojan horse' to fight mold invasions



Scientists have discovered that plants send tiny, innocuous-seeming lipid 'bubbles' filled with RNA across enemy lines, into the cells of the aggressive mold. Once inside, different types of RNA come out to suppress the infectious cells that sucked them in.
Published A trillion scents, one nose



A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities



The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published Study unveils a role of mitochondria in dietary fat processing



Researchers discover a new mechanism controlling the uptake of lipids from digested food.
Published Finding new ways to adapt to a growing weather threat



Research reveals a steady increase in the number of people at risk from tropical cyclones and the number of days per year these potentially catastrophic storms threaten health and livelihoods. The findings could help relief agencies, development banks, and other organizations plan more effective strategies for mitigating extreme weather impacts.
Published Scientists uncover link between the ocean's weather and global climate



Scientists outline the first direct evidence linking seemingly random weather systems in the ocean with climate on a global scale. The team's work creates a promising framework for better understanding the climate system.
Published Multitasking microbes: Scientists engineer bacteria to make two valuable products from plant fiber



Researchers have engineered bacteria that can produce two chemical products at the same time from underutilized plant fiber. And unlike humans, these multitasking microbes can do both things equally well. The discovery could help make biofuels more sustainable and commercially viable.
Published Reduced air pollution during pandemic points to way to preserve Himalayan glaciers



Reducing air pollution to levels similar to those during the coronavirus pandemic could protect the glaciers in the Himalayas and prevent them from disappearing by the end of the century. This is the conclusion reached by an international research team analyzing the situation during the COVID-19 lockdown in 2020.
Published World's smallest 'fanged' frogs found in Indonesia



Researchers have identified a species of frog new to science. The Indonesian amphibian is the size of a quarter, unlike its two-pound cousins, and has tiny fangs. Nearly uniquely among amphibians, they lay their eggs on the leaves of trees, and the males guard and tend to the nests.
Published The evolutionary timeline of diminished boric acid and urea transportation in aquaporin 10



Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells. However, Aqp10.2b in pufferfishes allows only the passage of water and glycerol and not urea and boric acid. Researchers sought to understand the evolutionary timeline that resulted in the variable substrate selection mechanisms among Aqp10s. Their results indicate that Aqp10.2 in ray-finned fishes may have reduced or lost urea and boric acid permeabilities through evolution.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells



Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Scientists provide recipe to halve pollution from food production



A major report has put forward solutions to halve nitrogen pollution from agriculture and the food system in Europe, including reducing meat and dairy consumption, fertilizer use and food waste. Inefficiencies in farms, retail and wastewater practices mean that the nitrogen use efficiency of the food system in Europe is only 18%, leaving most of the remainder leaking into air, water and soils. The new report, Appetite for Change, has been produced by a group of researchers coordinated by the UK Centre for Ecology & Hydrology (UKCEH), the European Commission, Copenhagen Business School and the National Institute for Public Health and the Environment (RIVM) of The Netherlands.