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Categories: Chemistry: Biochemistry, Environmental: General

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Antibody drug discovery is an extremely laborious and tedious process. Epitope Binning-seq, a novel method, introduces a groundbreaking approach by enabling simultaneous analysis of multiple antibodies. Using a fluorescently labeled reference antibody (rAb), this method employs flow cytometry to identify similar epitope-binding query antibodies (qAbs). Next-generation sequencing of fluorescence-negative cells then groups qAbs with epitopes akin to the rAb into epitope bins. This innovative technique holds immense potential in enhancing antibody drug discovery process.

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The United States has enough biomass potential to produce 35 billion gallons per year of aviation biofuel by 2050, a new report confirms.

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Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.

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Giving a regular cash payment to the entire world population has the potential to increase global gross domestic product (GDP) by 130%, according to a new analysis. Researchers suggest that charging carbon emitters with an emission tax could help fund such basic income program while reducing environmental degradation.

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Feed costs for producing broiler chickens accounts for 60% to 70% of total production costs, and stump waste from the production of button mushrooms comprises nearly 30% of total mushroom weight. Marrying the two has the potential to reduce both cost and waste, especially in Pennsylvania, which is a national leader in the production of broiler chickens and button mushrooms.

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A research team has found a de-icing mixture with high effectiveness and low environmental impact after using machine learning to analyze ice melting mechanisms of aqueous solutions of 21 salts and 16 organic solvents.

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New camera chip design allows for optimizing each pixel's timing to maximize signal to noise ratio when tracking real-time visual indicator of neural voltage.

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Researchers have discovered that the turbulence found in the thermosphere -- known as the gateway to space -- and turbulence in the troposphere, here closer to sea level, follow the same physical laws despite having drastically different atmospheric compositions and dynamics.

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Australia's ski industry is at risk of major disruptions and shorter seasons if the current level of climate pollution continues, according to new modelling. The report found the average ski season across all resorts in Australia will be 44 days shorter by 2050 under a mid-greenhouse gas emissions scenario and 55 days shorter under a high-emissions scenario.

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A research team has developed a liquid metal-based electronic logic device that mimics the intelligent prey-capture mechanism of Venus flytraps. Exhibiting memory and counting properties, the device can intelligently respond to various stimulus sequences without the need for additional electronic components. The intelligent strategies and logic mechanisms in the device provide a fresh perspective on understanding 'intelligence' in nature and offer inspiration for the development of 'embodied intelligence'.

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Little is yet known about the health effects of nanoparticles on pregnancy. An interdisciplinary team is currently analyzing the risks for babies in the womb. Using a lab model, the researchers were able to determine that certain nanoparticles impair the release of chemical messengers in the placenta and thus the formation of blood vessels.

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Advanced technologies enable the controlled release of medicine to specific cells in the body. Scientists argue these same technologies must be applied to agriculture if growers are to meet increasing global food demands.

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Current crises are distracting from the climate crisis and weakening support for climate action, a Europe-wide survey reveals.

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Tropical forests store a third of the world's carbon in their wood and soils. However, their future as a carbon sink has been uncertain. Scientists have long wondered whether nutrient-poor tropical soils would limit the ability of mature and recovering forests to thrive. A study offers a hopeful response, suggesting that forests have flexible strategies that help them overcome the challenge of scarce nutrients.

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Some say the next step in human evolution will be the integration of technology with flesh. Now, researchers have used virtual reality to test whether humans can feel embodiment -- the sense that something is part of one's body -- toward prosthetic 'hands' that resemble a pair of tweezers. They report that participants felt an equal degree of embodiment for the tweezer-hands and were also faster and more accurate in completing motor tasks in virtual reality than when they were equipped with a virtual human hand.

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Scientists are getting closer to detecting bushfires in record time, thanks to cube satellites with onboard AI now able to detect fires from space 500 times faster than traditional on-ground processing of imagery.

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Photographs making invisible air pollution visible have sparked discussion around the impact of air pollution on communities ascross the globe.

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Car tires contain hundreds of chemical additives that can leach out of them. This is how they end up in crops and subsequently in the food chain. Researchers have now detected these chemical residues in leafy vegetables for the first time. Although the concentrations were low, the evidence was clear, a finding that is also known for drug residues in plant-based foods.

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A collaborative team of researchers has made a cracking discovery with the potential to make a significant impact in the sustainable recovery of rare earth elements (REEs), which are in increasing demand for use in green energy technologies. The team found that humble eggshell waste could recover REES from water, offering a new, environmentally friendly method for their extraction.

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A team of researchers has developed a new method for target DNA sequence amplification, testing and analysis.