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Categories: Biology: Microbiology, Environmental: Ecosystems
Published Study shows engineered gut bacteria can treat hypertension
(via sciencedaily.com) Original source Newly published research proves that it's possible to treat high blood pressure by using specially engineered Lactobacillus paracasei to produce a protein called ACE2 in the gut, reducing gut angiotensin II and, in turn, lowering blood pressure. The study, done in lab rats that are predisposed to hypertension and unable to naturally produce ACE2, opens new doors in the pursuit of harnessing our body's own microbiome to regulate blood pressure.
Published How to slow the spread of deadly 'superbugs'
(via sciencedaily.com) Original source Harnessing new advances in genomic surveillance technology could help detect the rise of deadly 'superbugs'.
Published Gut fungi's lasting impact on severe COVID-19 immune response
(via sciencedaily.com) Original source Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study. This discovery identifies a group of patients who may benefit from specialized, but yet-to-be determined treatments.
Published Discovery finds ferns produce crop-saving insecticide
(via sciencedaily.com) Original source Researchers have solved the structure of a novel insecticidal protein that is effective in protecting major crop plants like corn and soybean from pests and is naturally produced by ferns.
Published Climate is increasing risk of high toxin concentrations in Northern US lakes
(via sciencedaily.com) Original source As climate change warms the Earth, higher-latitude regions will be at greater risk for toxins produced by algal blooms, according to new research. The findings identify water temperatures of 20 to 25 degrees Celsius (68 to 77 degrees Fahrenheit) as being at the greatest risk for developing dangerous levels of a common algae-produced toxin called microcystin.
Published Fungal evolution discovered: Mycena can now invade living hosts
(via sciencedaily.com) Original source Biologists have long known mushrooms of the genus Mycena, commonly known as bonnet mushrooms, as fungi that live off of dead trees and plants. New research demonstrates that bonnets can also find their ways into young, healthy trees and plants, where they try to cooperate. In doing so, they have made an evolutionary leap which challenges our understanding of the ecological roles of fungi.
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.
Published New study shows surprising effects of fire in North America's boreal forests
(via sciencedaily.com) Original source Using satellite images, researchers found that fires in North America's boreal forest may be changing the environment in ways that researchers didn't previously anticipate.
Published Contaminants in cannabis and hemp flowers create potential for health risks
(via sciencedaily.com) Original source Cannabis use, even for medical purposes, could make some people sick due to harmful fungi that contaminate the plants. That is the finding of a recently published peer-reviewed journal article, whose authors recommend further study and consideration of changes to regulations to protect consumers, especially those who are immunocompromised. They examined data, previous studies, and U.S. and international regulations related to the cannabis and hemp industry.
Published Moving muscle fibers with magnets 'programs' how they align within tissue
(via sciencedaily.com) Original source Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue. The findings offer a simpler, less time-consuming way for medical researchers to program muscle cell alignment, which is strongly tied to healthy muscle function.
Published How cord-like aggregates of bacteria lead to tuberculosis infections
(via sciencedaily.com) Original source The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. Investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.
Published Land use: Producing more food and storing more carbon
(via sciencedaily.com) Original source Doubling food production, saving water, and increasing carbon storage capacity -- this may sound paradoxical, but would be theoretically feasible considering the biophysical potential of the Earth. Reaching this goal, however, would require a radical spatial reorganization of land use.
Published Potential for injectable 'chemical vaccine' for malaria using atovaquone
(via sciencedaily.com) Original source Researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive. Malaria parasites in infected patients being treated with atovaquone tend to develop a resistance to the drug. Because of this, atovaquone by itself is not used as a malaria treatment nor has not been seen as a strong candidate for use as a preventive.
Published Dietary supplement modifies gut microbiome -- potential implications for bone marrow transplant patients
(via sciencedaily.com) Original source Researchers conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients. The study is the first part of a two-phase ongoing clinical trial evaluating the effect of modifying the microbiome on the incidence of graft-versus-host disease (GVHD), a major complication that develops in up to half the patients who receive a bone marrow transplant and can lead to injury and death.
Published Soil carried on sea freight loaded with dangerous pests and diseases, research finds
(via sciencedaily.com) Original source While sea freight is recognised as a pathway for the movement of exotic organisms, there is little research that has quantified the risk. Soil collected from the external surfaces of sea freight was found to support live microorganisms, worms, seeds and insects, including various regulated biosecurity organisms. The research confirms that shipping containers provide a pathway for the movement of exotic species.
Published Can golden retrievers live longer?
(via sciencedaily.com) Original source Researchers have found a gene associated with longevity in golden retrievers, one of the most popular breeds of dogs.
Published Unearthing the ecological impacts of cicada emergences on North American forests
(via sciencedaily.com) Original source New research unveils the cascading effects of periodical cicada emergence events on forest ecosystems ahead of an historic convergence of broods set to emerge spring of 2024.
Published You say genome editing, I say natural mutation
(via sciencedaily.com) Original source A plant geneticist and computational biologist teamed up to decipher the unpredictability of natural and engineered mutations in tomatoes. They discovered some combinations of mutations behave as expected while others are more erratic. Their work may help scientists find some order in the chaos of evolution and genome editing.
Published Scientists discover deepest known evidence of coral reef bleaching
(via sciencedaily.com) Original source Scientists have discovered the deepest known evidence of coral reef bleaching, more than 90 metres below the surface of the Indian Ocean. Identified during a research cruise, the damage to the deeper reefs in the Central Indian Ocean has been attributed to significant changes in the region's ocean temperature caused by the Indian Ocean Dipole. The researchers have also warned such incidences are only likely to increase as a result of present and future climate change.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.