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Categories: Chemistry: Biochemistry, Environmental: Wildfires

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Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects. This work opens up a new avenue to significantly enhance not only the signal quality, but also, overall nonivasive BCI performance by stimulating targeted neural circuits.

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CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or 'cancer dependencies,' are often promising drug targets. But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.

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Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.

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Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy.

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Layers of carbon atoms in a honeycomb array are a true supermaterial: their unusually high conductivity and favorable mechanical properties could further the development of bendable electronics, new batteries, and innovative composite materials for aeronautics and space flight. However, the development of elastic and tough films remains a challenge. A research team has now introduced a method to overcome this hurdle: they linked graphene nanolayers via 'extendable' bridging structures.

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Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.

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Scientists address decades-long problem in the field of single-molecule fluorescence resonance energy transfer, paving the way for more accurate experiments.

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Researchers have made a significant breakthrough in how to enable and exploit ultra-fast spin behavior in ferromagnets. The research paves the way for ultra-high frequency applications.

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Researchers have developed new chemistry to achieve commercially relevant stability and performance for perovskite solar cells.

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With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.

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A suite of three innovations enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution. To demonstrate the advance, researchers compared a brain region in an Alzheimer's and a control sample.

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A new machine-learning system can automatically produce detailed maps from satellite data to show locations of likely beetle-killed spruce trees in Alaska, even in forests of low and moderate infestation where identification is otherwise difficult. The automated process can help forestry and wildfire managers in their decisions. That's critical as the beetle infestation spreads.

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Engineers have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in mice, where it inhibited the growth and spread of tumors that had metastasized to the lungs, thereby boosting survival rates compared to control treatments.

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Louisiana's southeastern corridor is sometimes known colloquially as 'Cancer Alley' for its high cancer incidence rates connected to industrial air pollution. Most of the region's air pollution-related health risks are attributed to ethylene oxide, a volatile compound used to make plastics and sterilize medical equipment. Researchers measured concerning levels of ethylene oxide in this area with mobile optical instruments, a technique they say could improve health risk assessments.

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In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called 'symmetry breaking.'

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A team aims to improve options for renewable energy storage through work on an emerging technology -- liquids for hydrogen storage.

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Researchers have successfully used a new robot system to improve treatment for debilitating eye disease.

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Scientists have developed an artificial intelligence (AI)-powered system to track tiny devices that monitor markers of disease in the gut. Devices using the novel system may help at-risk individuals monitor their gastrointestinal (GI) tract health at home, without the need for invasive tests in hospital settings.

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Inspired by the material that makes up oyster and abalone shells, engineers have created a new cement composite that is 17 times more crack-resistant than standard cement and 19 times more able to stretch and deform without breaking. The findings could eventually help increase the crack resistance of a wide range of brittle ceramic materials from concrete to porcelain.

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The need to transition away from fossil fuels to more sustainable energy production is critical. That's why a team of researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.