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Categories: Chemistry: Biochemistry, Environmental: Water

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Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose. Researchers have now identified a strategy to design safer opioids. They showed that an experimental opioid, which binds to an unconventional spot in the receptor, suppresses pain in animal models with fewer side effects -- most notably those linked to fatal overdoses.

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A newly engineered type of soil can capture water out of thin air to keep plants hydrated and manage controlled release of fertilizer for a constant supply of nutrients.

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Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues -- it also lines and helps protect the lungs, stomach, intestines and eyes. And now, researchers have demonstrated in mice that their tiny, enzyme-powered 'snot bots' can push through the defensive, sticky layer and potentially deliver drugs more efficiently.

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CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.

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Researchers examine the specific impacts of microplastics on the geophysics of sea foam formation in the critical zone where water meets air in the top layer of the ocean. They devised two simulations for their work -- a column filled with sea water injected with air and a laboratory-scale breaking wave channel to test the impacts of wave height on sea foam in the surface microlayer -- and tested their effects on sea foam formation, stability, and duration.

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Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.

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Research achieves scientific breakthrough in understanding cell division.

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A new study reveals that Storm Ciaran cut an invisible path of mayhem across southern Britain last autumn, destroying any possibility that 20 million people could have a proper cup of tea at breakfast. The storm's record-breaking low pressure meant the boiling point of water was below the crucial 100 degrees Celsius required for a decent cuppa.

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Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.

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A new study finds that the proportional allocation of water, and not additional taxes on the resource, is more effective from the point of view of those engaged in agriculture.

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Carbon capture is a promising approach for mitigating carbon dioxide (CO2) emissions. Different materials have been used to capture CO2 from industrial exhaust gases. Scientists developed hybrid CO2 capture materials containing sodium carbonate and nanocarbon prepared at different temperatures, tested their performance, and identified the optimal calcination temperature condition. They found that the hybrid material exhibits and maintains high CO2 capture capacity for multiple regeneration cycles at a lower temperature, making it cost- and energy-effective.

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New research shows that ozone concentrations at Carlsbad Caverns National Park frequently exceed Environmental Protection Agency health standards, likely due to oil and natural gas development in the Permian Basin and surrounding region.

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A new study has unveiled surprising findings about mercury pollution: where it comes from and how it moves through the environment vary significantly depending on the ecosystem. In drier regions, most mercury is deposited through rain and snow. In wetter, forested areas, gaseous mercury from the air sticks to leaves, which then fall and carry the toxin into the ground.

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This new concept could allow the needs of previously separate industries to be combined: the production of hydrogen and the production of fertilizer.

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Oxygen is a fundamental requirement of life, and the loss of oxygen in water, referred to as aquatic deoxygenation, is a threat to life at all levels. In fact, researchers describe how ongoing deoxygenation presents a major threat to the stability of the planet as a whole.

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Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.

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Tree-planting campaigns have been underway in the United States, especially in cities, as part of climate mitigation efforts given the many environmental benefits of urban forests. But a new study finds that some areas within urban forests in the U.S., may be more capable than trees growing around city home lawns in adapting to a warmer climate.

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Researchers have successfully developed an environmentally friendly, microspherical fluorescent material primarily made from citric acid. These microbeads emit various colors of light depending on the illuminating light and the size of the beads, which suggests a wide range of applications. Furthermore, the use of plant-derived materials allows for low-cost and energy-efficient synthesis.

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Scientists have developed a tiny 'claw machine' that is able to pick up and drop a marble-sized ball in response to exposure to chemical vapors. The findings point to a technique that can enable soft actuators--the parts of a machine that make it move--to perform multiple tasks without the need for additional costly materials. While existing soft actuators can be 'one-trick ponies' restricted to one type of movement, this novel composite film contorts itself in different ways depending on the vapor that it is exposed to.

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Methane, a strong greenhouse gas that naturally escapes from the bottom of the North Sea, is affected by the pressure of high or low tide. Methane emissions from the seafloor can be just easily three times as much or as little, depending on the tide, according to a new study.